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Neuromorphic applications emulate the processing performed by the brain by using spikes as inputs instead of time-varying analog stimuli. Therefore, these time-varying stimuli have to be encoded into spikes, which can induce important…

Neural and Evolutionary Computing · Computer Science 2024-12-30 Ahmad El Ferdaoussi , Eric Plourde , Jean Rouat

A key question in neuroscience is at which level functional meaning emerges from biophysical phenomena. In most vertebrate systems, precise functions are assigned at the level of neural populations, while single-neurons are deemed…

Neurons and Cognition · Quantitative Biology 2017-03-17 Wieland Brendel , Ralph Bourdoukan , Pietro Vertechi , Christian K. Machens , Sophie Denéve

A complete single-neuron model must correctly reproduce the firing of spikes and bursts. We present a study of a simplified model of deep pyramidal cells of the cortex with active dendrites. We hypothesized that we can model the soma and…

Neurons and Cognition · Quantitative Biology 2013-12-04 Richard Naud , Brice Bathellier , Wulfram Gerstner

When brain signals are recorded in an electroencephalogram or some similar large-scale record of brain activity, oscillatory patterns are typically observed that are thought to reflect the aggregate electrical activity of the underlying…

Neurons and Cognition · Quantitative Biology 2013-06-04 Andre Nathan , Valmir C. Barbosa

Spikes are the currency in central nervous systems for information transmission and processing. They are also believed to play an essential role in low-power consumption of the biological systems, whose efficiency attracts increasing…

Neural and Evolutionary Computing · Computer Science 2020-05-05 Qiang Yu , Shenglan Li , Huajin Tang , Longbiao Wang , Jianwu Dang , Kay Chen Tan

In the last century, most sensorimotor studies of cortical neurons relied on average firing rates. Rate coding is efficient for fast sensorimotor processing that occurs within a few seconds. Much less is known about the neural mechanisms…

Neurons and Cognition · Quantitative Biology 2026-05-01 Terrence J. Sejnowski

Foundation models have shown remarkable success in fitting biological visual systems; however, their black-box nature inherently limits their utility for understanding brain function. Here, we peek inside a SOTA foundation model of neural…

Neurons and Cognition · Quantitative Biology 2025-12-10 Johannes Bertram , Luciano Dyballa , T. Anderson Keller , Savik Kinger , Steven W. Zucker

In recent years, there has been increasing interest in developing models and tools to address the complex patterns of connectivity found in brain tissue. Specifically, this is due to a need to understand how emergent properties emerge from…

Neurons and Cognition · Quantitative Biology 2022-04-15 Sean Knight , Navjot Gadda

Complementary Learning Systems theory holds that intelligent agents need two learning systems. Semantic memory is encoded in the neocortex with dense, overlapping representations and acquires structured knowledge. Episodic memory is encoded…

Machine Learning · Computer Science 2025-09-03 Lucie Fontaine , Frédéric Alexandre

The central problem with understanding brain and mind is the neural code issue: understanding the matter of our brain as basis for the phenomena of our mind. The richness with which our mind represents our environment, the parsimony of…

Neurons and Cognition · Quantitative Biology 2018-11-06 Christoph von der Malsburg

The hippocampal system contains neural populations that encode an animal's position and velocity as it navigates through space. Here, we show that such populations can embed two codes within their spike trains: a firing rate code (R)…

Neural and Evolutionary Computing · Computer Science 2019-12-25 Ryan Grgurich , Hugh T. Blair

Solving NP-hard/complete combinatorial problems with neural networks is a challenging research area that aims to surpass classical approximate algorithms. The long-term objective is to outperform hand-designed heuristics for…

Neural and Evolutionary Computing · Computer Science 2024-02-14 Dobrik Georgiev , Danilo Numeroso , Davide Bacciu , Pietro Liò

Why do neurons encode information the way they do? Normative answers to this question model neural activity as the solution to an optimisation problem; for example, the celebrated efficient coding hypothesis frames neural activity as the…

Neurons and Cognition · Quantitative Biology 2026-03-06 William Dorrell , Peter E. Latham , James Whittington

We study a reinforcement learning for temporal coding with neural network consisting of stochastic spiking neurons. In neural networks, information can be coded by characteristics of the timing of each neuronal firing, including the order…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Daichi Kimura , Yoshinori Hayakawa

There is extensive evidence that biological neural networks encode information in the precise timing of the spikes generated and transmitted by neurons, which offers several advantages over rate-based codes. Here we adopt a vector space…

Neurons and Cognition · Quantitative Biology 2019-07-16 Dorian Florescu , Daniel Coca

Spike patterns have been reported to encode sensory information in several brain areas. Here we assess the role of specific patterns in the neural code, by comparing the amount of information transmitted with different choices of the…

Quantitative Methods · Quantitative Biology 2009-12-14 Hugo Gabriel Eyherabide , Ines Samengo

The neural coding is yet to be discovered. The neuronal operational modes that arise with fixed inputs but with varying degrees of stimulation help to elucidate their coding properties. In neurons receiving {\it in vivo} stimulation, we…

Neurons and Cognition · Quantitative Biology 2025-11-05 Lindsey Knowles , Cesar Ceballos , Rodrigo Pena

The brain is organized in a modular way, serving multiple functionalities. This multiplicity requires that both positive (e.g. excitatory, phase-coherent) and negative (e.g. inhibitory, phase-opposing) interactions take place across brain…

Neurons and Cognition · Quantitative Biology 2019-07-29 Assaf Almog , Ori Roethler , Renate Buijink , Stephan Michel , Johanna H Meijer , Jos H. T. Rohling , Diego Garlaschelli

To evaluate the nature of the neural code in the cerebral cortex, we have used a combination of theory and experiment to assess how information is represented in a realistic cortical population response. We have shown how a sensory stimulus…

Neurons and Cognition · Quantitative Biology 2008-03-28 L. C. Osborne , S. E. Palmer , S. G. Lisberger , W. Bialek

Sequence learning, prediction and replay have been proposed to constitute the universal computations performed by the neocortex. The Hierarchical Temporal Memory (HTM) algorithm realizes these forms of computation. It learns sequences in an…

Neurons and Cognition · Quantitative Biology 2022-07-21 Younes Bouhadjar , Dirk J. Wouters , Markus Diesmann , Tom Tetzlaff