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Motivated by the increasing number of COVID-19 cases that have been observed in many countries after the vaccination and relaxation of non-pharmaceutical interventions, we propose a mathematical model on time-varying networks for the spread…

Dynamical Systems · Mathematics 2022-03-09 Kathinka Frieswijk , Lorenzo Zino , Ming Cao

This paper presents a study on a compartmental epidemic model for COVID-19, examining the stability of its equilibrium points upon the introduction of vaccination as a strategy to mitigate the spread of the disease. Initially, the SIQR…

Numerical Analysis · Mathematics 2024-05-29 Leonardo R. S. Rodrigues , Felipe Gabrielli

Compartmental epidemic models have been widely used for predicting the course of epidemics, from estimating the basic reproduction number to guiding intervention policies. Studies commonly acknowledge these models' assumptions but less…

Populations and Evolution · Quantitative Biology 2022-11-23 Alexander F. Siegenfeld , Pratyush K. Kollepara , Yaneer Bar-Yam

We introduce a methodology to guarantee safety against the spread of infectious diseases by viewing epidemiological models as control systems and by considering human interventions (such as quarantining or social distancing) as control…

Systems and Control · Electrical Eng. & Systems 2022-11-21 Tamas G. Molnar , Andrew W. Singletary , Gabor Orosz , Aaron D. Ames

This paper is a survey paper on stochastic epidemic models. A simple stochastic epidemic model is defined and exact and asymptotic model properties (relying on a large community) are presented. The purpose of modelling is illustrated by…

Probability · Mathematics 2009-11-05 Tom Britton

The adoption of containment measures to reduce the amplitude of the epidemic peak is a key aspect in tackling the rapid spread of an epidemic. Classical compartmental models must be modified and studied to correctly describe the effects of…

Populations and Evolution · Quantitative Biology 2021-05-18 G. Albi , L. Pareschi , M. Zanella

In order to model an epidemic, different approaches can be adopted. Mainly, the deterministic approach and the stochastic one. Recently, a large amount of literature has been published using the two approaches. The aim of this paper is to…

Populations and Evolution · Quantitative Biology 2023-01-30 Mohamed Mehdaoui

Since the start of the still ongoing COVID-19 pandemic, there have been many modeling efforts to assess several issues of importance to public health. In this work, we review the theory behind some important mathematical models that have…

Populations and Evolution · Quantitative Biology 2022-01-06 Fernando Saldaña , Jorge X Velasco-Hernández

Classical compartmental models in epidemiology often assume a homogeneous population for simplicity, which neglects the inherent heterogeneity among individuals. This assumption frequently leads to inaccurate predictions when applied to…

Populations and Evolution · Quantitative Biology 2024-09-09 Ning Jiang , Weiqi Chu , Yao Li

Epidemic outbreaks pose significant challenges to public health and socio-economic stability, necessitating a comprehensive understanding of disease transmission dynamics and effective control strategies. This article discusses the…

Physics and Society · Physics 2023-10-20 Sourin Chatterjee , Ahad N. Zehmakan , Sujay Rastogi

In this research, we develop a framework to analyze the interaction between the economy and the Covid-19 pandemic using an extension of SIR epidemic model. At the outset, we assume there are two health related investments including general…

Optimization and Control · Mathematics 2022-02-14 Zachariah Sinkala , Vajira Manathunga , Bichaka Fayissa

Motivated by the issue of COVID-19 mitigation, in this work we tackle the general problem of optimally controlling an epidemic outbreak of a communicable disease structured by time since exposure, by the aid of two types of control…

Populations and Evolution · Quantitative Biology 2024-05-13 Alberto d'Onofrio , Mimmo Iannelli , Piero Manfredi , Gabriela Marinoschi

Epidemiological models are an important tool in coping with epidemics, as they offer a forecast, even if often simplistic, of the behavior of the disease in the population. This allows responsible health agencies to organize themselves and…

Populations and Evolution · Quantitative Biology 2023-08-03 Eliza Maria Ferreira , Ricardo Edem Ferreira , Chiara Mocenni

Successful predictive modeling of epidemics requires an understanding of the implicit feedback control strategies which are implemented by populations to modulate the spread of contagion. While this task of capturing endogenous behavior can…

Populations and Evolution · Quantitative Biology 2022-03-31 Ali Jadbabaie , Arnab Sarker , Devavrat Shah

We consider the SEIRS epidemiology model with such features of the COVID-19 outbreak as: abundance of unidentified infected individuals, limited time of immunity and a possibility of vaccination. The control of the pandemic dynamics is…

Populations and Evolution · Quantitative Biology 2026-03-31 J. Ilnytskyi , T. Patsahan

We analyze an epidemic model on a network consisting of susceptible-infected-recovered equations at the nodes coupled by diffusion using a graph Laplacian. We introduce an epidemic criterion and examine different vaccination/containment…

Physics and Society · Physics 2020-09-25 F. Bustamante-Castaneda , J. -G. Caputo , G. Cruz-Pacheco , A. Knippel , F. Mouatamide

This work introduces a novel epidemiological model that simultaneously considers multiple viral strains, reinfections due to waning immunity response over time and an optimal control formulation. This enables us to derive optimal mitigation…

Systems and Control · Electrical Eng. & Systems 2021-09-10 Edilson F. Arruda , Dayse H. Pastore , Clauda M. Dias , Shyam S. Das

In this study, we present a new epidemiological model, with contamination from confirmed and unreported. We also compute equilibria and study their stability without intervention strategies. Optimal control theory has proven to be a…

Populations and Evolution · Quantitative Biology 2020-08-14 Fulgence Mansal , Mouhamadou A. M. T. Baldé , Alpha O. Bah

We introduce a general system of ordinary differential equations that includes some classical and recent models for the epidemic spread in a closed population without vital dynamic in a finite time horizon. The model is vectorial, in the…

Optimization and Control · Mathematics 2023-06-21 Lorenzo Freddi

The waning of immunity after recovery or vaccination is a major factor accounting for the severity and prolonged duration of an array of epidemics, ranging from COVID-19 to diphtheria and pertussis. To study the effectiveness of different…

Dynamical Systems · Mathematics 2023-02-01 Shoshana Elgart
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