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Related papers: Cascade RCNN for MIDOG Challenge

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For the MIDOG mitosis detection challenge, we created a cascade algorithm consisting of a Mask-RCNN detector, followed by a classification ensemble consisting of ResNet50 and DenseNet201 to refine detected mitotic candidates. The MIDOG…

Computer Vision and Pattern Recognition · Computer Science 2021-09-30 Gauthier Roy , Jules Dedieu , Capucine Bertrand , Alireza Moshayedi , Ali Mammadov , Stéphanie Petit , Saima Ben Hadj , Rutger H. J. Fick

Mitotic count (MC) is an important histological parameter for cancer diagnosis and grading, but the manual process for obtaining MC from whole-slide histopathological images is very time-consuming and prone to error. Therefore, deep…

Computer Vision and Pattern Recognition · Computer Science 2022-03-01 Chawan Piansaddhayanon , Sakun Santisukwongchote , Shanop Shuangshoti , Qingyi Tao , Sira Sriswasdi , Ekapol Chuangsuwanich

This is the submission for mitosis detection in the context of the MIDOG 2021 challenge. It is based on the two-stage objection model Faster RCNN as well as DenseNet as a backbone for the neural network architecture. It achieves a F1-score…

Computer Vision and Pattern Recognition · Computer Science 2021-09-03 Michel Halmes , Hippolyte Heuberger , Sylvain Berlemont

Mitosis detection is one of the challenging problems in computational pathology, and mitotic count is an important index of cancer grading for pathologists. However, current counts of mitotic nuclei rely on pathologists looking…

Computer Vision and Pattern Recognition · Computer Science 2023-01-19 Huadeng Wang , Hao Xu , Bingbing Li , Xipeng Pan , Lingqi Zeng , Rushi Lan , Xiaonan Luo

Studies estimate that there will be 266,120 new cases of invasive breast cancer and 40,920 breast cancer induced deaths in the year of 2018 alone. Despite the pervasiveness of this affliction, the current process to obtain an accurate…

Computer Vision and Pattern Recognition · Computer Science 2018-07-06 Siddhant Rao

The proliferative activity of breast tumors, which is routinely estimated by counting of mitotic figures in hematoxylin and eosin stained histology sections, is considered to be one of the most important prognostic markers. However, mitosis…

Each woman living in the United States has about 1 in 8 chance of developing invasive breast cancer. The mitotic cell count is one of the most common tests to assess the aggressiveness or grade of breast cancer. In this prognosis,…

Computer Vision and Pattern Recognition · Computer Science 2022-02-18 Robin Elizabeth Yancey

Mitosis nuclei count is one of the important indicators for the pathological diagnosis of breast cancer. The manual annotation needs experienced pathologists, which is very time-consuming and inefficient. With the development of deep…

Computer Vision and Pattern Recognition · Computer Science 2022-12-29 Huadeng Wang , Zhipeng Liu , Rushi Lan , Zhenbing Liu , Xiaonan Luo , Xipeng Pan , Bingbing Li

Counting of mitotic figures is a fundamental step in grading and prognostication of several cancers. However, manual mitosis counting is tedious and time-consuming. In addition, variation in the appearance of mitotic figures causes a high…

Computer Vision and Pattern Recognition · Computer Science 2023-09-26 Mostafa Jahanifar , Adam Shephard , Neda Zamanitajeddin , Simon Graham , Shan E Ahmed Raza , Fayyaz Minhas , Nasir Rajpoot

Mitotic figure detection remains a challenging task in computational pathology due to domain variability and morphological complexity. This paper describes our participation in the MIDOG 2025 challenge, focusing on robust mitotic figure…

Image and Video Processing · Electrical Eng. & Systems 2025-09-04 Euiseop Song , Jaeyoung Park , Jaewoo Park

We present a summary of the domain adaptive cascade R-CNN method for mitosis detection of digital histopathology images. By comprehensive data augmentation and adapting existing popular detection architecture, our proposed method has…

Image and Video Processing · Electrical Eng. & Systems 2021-09-30 Xi Long , Ying Cheng , Xiao Mu , Lian Liu , Jingxin Liu

Automated mitotic detection in time-lapse phasecontrast microscopy provides us much information for cell behavior analysis, and thus several mitosis detection methods have been proposed. However, these methods still have two problems; 1)…

Machine Learning · Computer Science 2020-06-02 Kazuya Nishimura , Ryoma Bise

Mitotic figure (MF) detection in histopathology images is challenging due to large variations in slide scanners, staining protocols, tissue types, and the presence of artifacts. This paper presents a collection of training techniques - a…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Christian Marzahl , Brian Napora

Empirical evaluation of breast tissue biopsies for mitotic nuclei detection is considered an important prognostic biomarker in tumor grading and cancer progression. However, automated mitotic nuclei detection poses several challenges…

Computer Vision and Pattern Recognition · Computer Science 2020-03-20 Anabia Sohail , Muhammad Ahsan Mukhtar , Asifullah Khan , Muhammad Mohsin Zafar , Aneela Zameer , Saranjam Khan

In certain types of cancerous tissue, mitotic count has been shown to be associated with tumor proliferation, poor prognosis, and therapeutic resistance. Due to the high inter-rater variability of mitotic counting by pathologists,…

Computer Vision and Pattern Recognition · Computer Science 2023-10-12 Ruiwen Ding , James Hall , Neil Tenenholtz , Kristen Severson

Mitotic count is the most important morphological feature of breast cancer grading. Many deep learning-based methods have been proposed but suffer from domain shift. In this work, we construct a Fourier-based segmentation model for mitosis…

Image and Video Processing · Electrical Eng. & Systems 2021-10-20 Sen Yang , Feng Luo , Jun Zhang , Xiyue Wang

We present a novel approach which extends the existing Fully Convolutional One-Stage Object Detector (FCOS) for mitotic figure detection. Our composite model adds a Feedback Attention Ladder CNN (FAL-CNN) model for classification of normal…

Image and Video Processing · Electrical Eng. & Systems 2025-09-22 Andrew Broad , Jason Keighley , Lucy Godson , Alex Wright

MIDOG 2025 Track 1 requires mitosis detection in whole-slideimages (WSIs) containing non-tumor, inflamed, and necrotic re-gions. Due to the complicated and heterogeneous context, aswell as possible artifacts, there are often false positives…

Image and Video Processing · Electrical Eng. & Systems 2025-09-29 Jie Xiao , Mengye Lyu , Shaojun Liu

The account of mitotic cells is a key feature in tumor diagnosis. However, due to the variability of mitotic cell morphology, it is a highly challenging task to detect mitotic cells in tumor tissues. At the same time, although advanced deep…

Computer Vision and Pattern Recognition · Computer Science 2022-08-29 Chen Yang , Wang Ziyue , Fang Zijie , Bian Hao , Zhang Yongbing

This work presents a mitosis detection method with only one vanilla Convolutional Neural Network (CNN). Our method consists of two steps: given an image, we first apply a CNN using a sliding window technique to extract patches that have…

Computer Vision and Pattern Recognition · Computer Science 2022-11-01 Hongyan Gu , Mohammad Haeri , Shuo Ni , Christopher Kazu Williams , Neda Zarrin-Khameh , Shino Magaki , Xiang 'Anthony' Chen
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