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Related papers: Stain-Robust Mitotic Figure Detection for the Mito…

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The count of mitotic figures (MFs) observed in hematoxylin and eosin (H&E)-stained slides is an important prognostic marker as it is a measure for tumor cell proliferation. However, the identification of MFs has a known low inter-rater…

The domain shift between training and testing data presents a significant challenge for training generalizable deep learning models. As a consequence, the performance of models trained with the independent and identically distributed…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Aleksandr Matsun , Dana O. Mohamed , Sharon Chokuwa , Muhammad Ridzuan , Mohammad Yaqub

Deep learning is expected to aid pathologists by automating tasks such as tumour segmentation. We aimed to develop one universal tumour segmentation model for histopathological images and examine its performance in different cancer types.…

Histopathological images provide rich information for disease diagnosis. Large numbers of histopathological images have been digitized into high resolution whole slide images, opening opportunities in developing computational image analysis…

Image and Video Processing · Electrical Eng. & Systems 2020-11-06 Jiayun Li , Wenyuan Li , Anthony Sisk , Huihui Ye , W. Dean Wallace , William Speier , Corey W. Arnold

Digital image forensics aims to detect images that have been digitally manipulated. Realistic image forgeries involve a combination of splicing, resampling, region removal, smoothing and other manipulation methods. While most detection…

Computer Vision and Pattern Recognition · Computer Science 2021-04-13 Lakshmanan Nataraj , Michael Goebel , Tajuddin Manhar Mohammed , Shivkumar Chandrasekaran , B. S. Manjunath

Medical image segmentation plays an important role in clinical decision making, treatment planning, and disease tracking. However, it still faces two major challenges. On the one hand, there is often a ``soft boundary'' between foreground…

Image and Video Processing · Electrical Eng. & Systems 2024-12-12 Mengqi Lei , Haochen Wu , Xinhua Lv , Xin Wang

Mitotic figures (MFs) are relevant biomarkers in tumor grading. Differentiating atypical MFs (AMFs) from normal MFs (NMFs) remains difficult, as manual annotation is time-consuming and subjective. In this work an ensemble of ConvNeXtBase…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Sara Krauss , Ellena Spieß , Daniel Hieber , Frank Kramer , Johannes Schobel , Dominik Müller

Challenges have become the state-of-the-art approach to benchmark image analysis algorithms in a comparative manner. While the validation on identical data sets was a great step forward, results analysis is often restricted to pure ranking…

The reliability of Deep Learning systems depends on their accuracy but also on their robustness against adversarial perturbations to the input data. Several attacks and defenses have been proposed to improve the performance of Deep Neural…

Computer Vision and Pattern Recognition · Computer Science 2021-07-12 Laura Daza , Juan C. Pérez , Pablo Arbeláez

The integrity of the reconstructed human epidermis generated in vitro could be assessed using histological analyses combined with immunohistochemical staining of keratinocyte differentiation markers. Computer-based analysis of scanned…

Image and Video Processing · Electrical Eng. & Systems 2025-12-01 Dawid Zamojski , Agnieszka Gogler , Dorota Scieglinska , Michal Marczyk

An important part of Digital Pathology is the analysis of multiple digitised whole slide images from differently stained tissue sections. It is common practice to mount consecutive sections containing corresponding microscopic structures on…

Computer Vision and Pattern Recognition · Computer Science 2018-11-06 Thomas Lampert , Odyssée Merveille , Jessica Schmitz , Germain Forestier , Friedrich Feuerhake , Cédric Wemmert

The MiDeSeC dataset is created through H&E stained invasive breast carcinoma, no special type (NST) slides of 25 different patients captured at 40x magnification from the Department of Medical Pathology at Ankara University. The slides have…

Image and Video Processing · Electrical Eng. & Systems 2025-07-22 Refik Samet , Nooshin Nemati , Emrah Hancer , Serpil Sak , Bilge Ayca Kirmizi , Zeynep Yildirim

We cast the problem of image denoising as a domain translation problem between high and low noise domains. By modifying the cycleGAN model, we are able to learn a mapping between these domains on unpaired retinal optical coherence…

Image and Video Processing · Electrical Eng. & Systems 2019-11-19 Ilja Manakov , Markus Rohm , Christoph Kern , Benedikt Schworm , Karsten Kortuem , Volker Tresp

Machine learning models for medical image analysis often suffer from poor performance on important subsets of a population that are not identified during training or testing. For example, overall performance of a cancer detection model may…

Machine Learning · Computer Science 2019-11-18 Luke Oakden-Rayner , Jared Dunnmon , Gustavo Carneiro , Christopher Ré

Since the introduction of digital and computational pathology as a field, one of the major problems in the clinical application of algorithms has been the struggle to generalize well to examples outside the distribution of the training…

Image and Video Processing · Electrical Eng. & Systems 2023-01-10 Quoc Dang Vu , Robert Jewsbury , Simon Graham , Mostafa Jahanifar , Shan E Ahmed Raza , Fayyaz Minhas , Abhir Bhalerao , Nasir Rajpoot

Meningioma is one of the most prevalent brain tumors in adults. To determine its malignancy, it is graded by a pathologist into three grades according to WHO standards. This grade plays a decisive role in treatment, and yet may be subject…

Detection of visual anomalies refers to the problem of finding patterns in different imaging data that do not conform to the expected visual appearance and is a widely studied problem in different domains. Due to the nature of anomaly…

Image and Video Processing · Electrical Eng. & Systems 2021-04-29 Dejan Stepec , Danijel Skocaj

Digital pathology and microscopy image analysis are widely employed in the segmentation of digitally scanned IHC slides, primarily to identify cancer and pinpoint regions of interest (ROI) indicative of tumor presence. However, current ROI…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Akash Modi , Sumit Kumar Jha , Purnendu Mishra , Rajiv Kumar , Kiran Aatre , Gursewak Singh , Shubham Mathur

In order to improve the detection and classification of malignant melanoma, this paper describes an image-based method that can achieve AUROC values of up to 0.78 without additional clinical information. Furthermore, the importance of the…

Image and Video Processing · Electrical Eng. & Systems 2023-06-13 Julian Burghoff , Leonhard Ackermann , Younes Salahdine , Veronika Bram , Katharina Wunderlich , Julius Balkenhol , Thomas Dirschka , Hanno Gottschalk

This study focuses on automatic skin cancer detection using a Meta-learning approach for dermoscopic images. The aim of this study is to explore the benefits of the generalization of the knowledge extracted from non-medical data in the…

Computer Vision and Pattern Recognition · Computer Science 2021-04-23 Sara I. Garcia