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We propose a virtual staining methodology based on Generative Adversarial Networks to map histopathology images of breast cancer tissue from H&E stain to PHH3 and vice versa. We use the resulting synthetic images to build Convolutional…
Image denoising is a classical problem in low level computer vision. Model-based optimization methods and deep learning approaches have been the two main strategies for solving the problem. Model-based optimization methods are flexible for…
Recent advances in computer-aided diagnosis for histopathology have been largely driven by the use of deep learning models for automated image analysis. While these networks can perform on par with medical experts, their performance can be…
Standard of care diagnostic procedure for suspected skin cancer is microscopic examination of hematoxylin \& eosin stained tissue by a pathologist. Areas of high inter-pathologist discordance and rising biopsy rates necessitate higher…
Medical image segmentation assists in computer-aided diagnosis, surgeries, and treatment. Digitize tissue slide images are used to analyze and segment glands, nuclei, and other biomarkers which are further used in computer-aided medical…
Automated detection of sclerotic metastases (bone lesions) in Computed Tomography (CT) images has potential to be an important tool in clinical practice and research. State-of-the-art methods show performance of 79% sensitivity or…
The International Symposium on Biomedical Imaging (ISBI) held a grand challenge to evaluate computational systems for the automated detection of metastatic breast cancer in whole slide images of sentinel lymph node biopsies. Our team won…
Segmentation of histological images is one of the most crucial tasks for many biomedical analyses including quantification of certain tissue type. However, challenges are posed by high variability and complexity of structural features in…
We present a self-supervised algorithm for several classification tasks within hematoxylin and eosin (H&E) stained images of breast cancer. Our method is robust to stain variations inherent to the histology images acquisition process, which…
Histopathology images; microscopy images of stained tissue biopsies contain fundamental prognostic information that forms the foundation of pathological analysis and diagnostic medicine. However, diagnostics from histopathology images…
Deep learning has significantly advanced medical imaging analysis, yet variations in image resolution remain an overlooked challenge. Most methods address this by resampling images, leading to either information loss or computational…
Cervical intraepithelial neoplasia (CIN) grade of histopathology images is a crucial indicator in cervical biopsy results. Accurate CIN grading of epithelium regions helps pathologists with precancerous lesion diagnosis and treatment…
This paper explores the application of Human-in-the-Loop (HITL) strategies in training machine learning models in the medical domain. In this case a doctor-in-the-loop approach is proposed to leverage human expertise in dealing with large…
Diagnostic imaging has gained prominence as potential biomarkers for early detection and diagnosis in a diverse array of disorders including cancer. However, existing methods routinely face challenges arising from various factors such as…
Robust unsupervised anomaly detection (AD) in real-world scenarios is an important task. Current methods exhibit severe performance degradation on the MVTec AD 2 benchmark due to its complex real-world challenges. To solve this problem, we…
Recently, various deep learning methods have shown significant successes in medical image analysis, especially in the detection of cancer metastases in hematoxylin and eosin (H&E) stained whole-slide images (WSIs). However, in order to…
The classification of histopathological images is of great value in both cancer diagnosis and pathological studies. However, multiple reasons, such as variations caused by magnification factors and class imbalance, make it a challenging…
Ocular Myasthenia Gravis (OMG) is a rare and challenging disease to detect in its early stages, but symptoms often first appear in the eye muscles, such as drooping eyelids and double vision. Ocular images can be used for early diagnosis by…
Intraoperative tracking of laparoscopic instruments is often a prerequisite for computer and robotic-assisted interventions. While numerous methods for detecting, segmenting and tracking of medical instruments based on endoscopic video…
Accurate and robust medical image classification is a challenging task, especially in application domains where available annotated datasets are small and present high imbalance between target classes. Considering that data acquisition is…