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A novel deep learning architecture (XmasNet) based on convolutional neural networks was developed for the classification of prostate cancer lesions, using the 3D multiparametric MRI data provided by the PROSTATEx challenge. End-to-end…

Computer Vision and Pattern Recognition · Computer Science 2017-03-14 Saifeng Liu , Huaixiu Zheng , Yesu Feng , Wei Li

In deep learning, transfer learning and ensemble models have shown promise in improving computer-aided disease diagnosis. However, applying the transfer learning and ensemble model is still relatively limited. Moreover, the ensemble model's…

Image and Video Processing · Electrical Eng. & Systems 2024-09-11 Md Taimur Ahad , Sumaya Mustofa , Faruk Ahmed , Yousuf Rayhan Emon , Aunirudra Dey Anu

Early cancer detection remains one of the most critical challenges in modern healthcare, where delayed diagnosis significantly reduces survival outcomes. Recent advancements in artificial intelligence, particularly deep learning, have…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Emmanuella Avwerosuoghene Oghenekaro

Epigenetic alterations have an important role in the development of several types of cancer. Epigenetic studies generate a large amount of data, which makes it essential to develop novel models capable of dealing with large-scale data. In…

Machine Learning · Computer Science 2021-02-22 del Amor Rocío , Colomer Adrián , Monteagudo Carlos , Naranjo Valery

Brain tumors are serious health problems that require early diagnosis due to their high mortality rates. Diagnosing tumors by examining Magnetic Resonance Imaging (MRI) images is a process that requires expertise and is prone to error.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Mustafa Yurdakul , Şakir Taşdemir

Breast cancer remains a leading cause of cancer-related mortality worldwide. Early detection is critical, yet manual histopathology analysis is complex and subject to inter-observer variability. While deep neural network-based diagnostic…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Gul Sheeraz , Qun Chen , Liu Feiyu , Zhou Fengjin

The International Symposium on Biomedical Imaging (ISBI) held a grand challenge to evaluate computational systems for the automated detection of metastatic breast cancer in whole slide images of sentinel lymph node biopsies. Our team won…

Quantitative Methods · Quantitative Biology 2016-06-21 Dayong Wang , Aditya Khosla , Rishab Gargeya , Humayun Irshad , Andrew H. Beck

Breast cancer, the most common malignancy among women, requires precise detection and classification for effective treatment. Immunohistochemistry (IHC) biomarkers like HER2, ER, and PR are critical for identifying breast cancer subtypes.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Ekansh Chauhan , Anila Sharma , Amit Sharma , Vikas Nishadham , Asha Ghughtyal , Ankur Kumar , Gurudutt Gupta , Anurag Mehta , C. V. Jawahar , P. K. Vinod

Histology imaging is an essential diagnosis method to finalize the grade and stage of cancer of different tissues, especially for breast cancer diagnosis. Specialists often disagree on the final diagnosis on biopsy tissue due to the complex…

Computer Vision and Pattern Recognition · Computer Science 2019-09-17 Yongxiang Huang , Albert Chi-shing Chung

Automated detection of mitotic figures in histopathology images has seen vast improvements, thanks to modern deep learning-based pipelines. Application of these methods, however, is in practice limited by strong variability of images…

Computer Vision and Pattern Recognition · Computer Science 2021-03-31 Marc Aubreville , Christof Bertram , Mitko Veta , Robert Klopfleisch , Nikolas Stathonikos , Katharina Breininger , Natalie ter Hoeve , Francesco Ciompi , Andreas Maier

Breast cancer is the most frequently diagnosed cancer and leading cause of cancer-related death among females worldwide. In this article, we investigate the applicability of densely connected convolutional neural networks to the problems of…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Matthias Kohl , Christoph Walz , Florian Ludwig , Stefan Braunewell , Maximilian Baust

Automatization of the diagnosis of any kind of disease is of great importance and it's gaining speed as more and more deep learning solutions are applied to different problems. One of such computer aided systems could be a decision support…

Computer Vision and Pattern Recognition · Computer Science 2018-04-24 Tomas Iesmantas , Robertas Alzbutas

In this paper we discuss lung cancer detection using hybrid model of Convolutional-Neural-Networks (CNNs) and Support-Vector-Machines-(SVMs) in order to gain early detection of tumors, benign or malignant. The work uses this hybrid model by…

Image and Video Processing · Electrical Eng. & Systems 2025-01-14 Aryan Chaudhari , Ankush Singh , Sanchi Gajbhiye , Pratham Agrawal

We present a deep learning framework for computer-aided lung cancer diagnosis. Our multi-stage framework detects nodules in 3D lung CAT scans, determines if each nodule is malignant, and finally assigns a cancer probability based on these…

Computer Vision and Pattern Recognition · Computer Science 2017-05-29 Kingsley Kuan , Mathieu Ravaut , Gaurav Manek , Huiling Chen , Jie Lin , Babar Nazir , Cen Chen , Tse Chiang Howe , Zeng Zeng , Vijay Chandrasekhar

Atypical mitosis marks a deviation in the cell division process that has been shown be an independent prognostic marker for tumor malignancy. However, atypical mitosis classification remains challenging due to low prevalence, at times…

Breast density classification is an essential part of breast cancer screening. Although a lot of prior work considered this problem as a task for learning algorithms, to our knowledge, all of them used small and not clinically realistic…

Computer Vision and Pattern Recognition · Computer Science 2017-11-13 Nan Wu , Krzysztof J. Geras , Yiqiu Shen , Jingyi Su , S. Gene Kim , Eric Kim , Stacey Wolfson , Linda Moy , Kyunghyun Cho

Automated methods for breast cancer detection have focused on 2D mammography and have largely ignored 3D digital breast tomosynthesis (DBT), which is frequently used in clinical practice. The two key challenges in developing automated…

Computer Vision and Pattern Recognition · Computer Science 2020-02-28 Yu Zhang , Xiaoqin Wang , Hunter Blanton , Gongbo Liang , Xin Xing , Nathan Jacobs

Machine learning and artificial intelligence are fast-growing fields of research in which data is used to train algorithms, learn patterns, and make predictions. This approach helps to solve seemingly intricate problems with significant…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Shereiff Garrett , Abhinav Adhikari , Sarina Gautam , DaShawn Marquis Morris , Chandra Mani Adhikari

Technology-assisted platforms provide reliable solutions in almost every field these days. One such important application in the medical field is the skin cancer classification in preliminary stages that need sensitive and precise data…

Image and Video Processing · Electrical Eng. & Systems 2020-03-16 Muhammad Ali Farooq , Asma Khatoon , Viktor Varkarakis , Peter Corcoran

Cancer is an extremely difficult and dangerous health problem because it manifests in so many different ways and affects so many different organs and tissues. The primary goal of this research was to evaluate deep learning models' ability…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 İrem Sayın , Muhammed Ali Soydaş , Yunus Emre Mert , Arda Yarkataş , Berk Ergun , Selma Sözen Yeh , Hüseyin Üvet