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We present deformable unsupervised medical image registration using a randomly-initialized deep convolutional neural network (CNN) as regularization prior. Conventional registration methods predict a transformation by minimizing…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Max-Heinrich Laves , Sontje Ihler , Tobias Ortmaier

Small animal PET scanners require high spatial resolution and good sensitivity. To reconstruct high-resolution images in 3D-PET, iterative methods, such as OSEM, are superior to analytical reconstruction algorithms, although their high…

Medical Physics · Physics 2007-05-23 J. L. Herraiz , S. Espana , J. J. Vaquero , M. Desco , J. M. Udias

Reconstructing 3D cone beam computed tomography (CBCT) images from a limited set of projections is an important inverse problem in many imaging applications from medicine to inertial confinement fusion (ICF). The performance of traditional…

Image and Video Processing · Electrical Eng. & Systems 2025-10-06 Xiaojian Xu , Marc Klasky , Michael T. McCann , Jason Hu , Jeffrey A. Fessler

We present a lossy image compression method based on deep convolutional neural networks (CNNs), which outperforms the existing BPG, WebP, JPEG2000 and JPEG as measured via multi-scale structural similarity (MS-SSIM), at the same bit rate.…

Image and Video Processing · Electrical Eng. & Systems 2018-06-06 Haojie Liu , Tong Chen , Qiu Shen , Tao Yue , Zhan Ma

In "extreme" computational imaging that collects extremely undersampled or noisy measurements, obtaining an accurate image within a reasonable computing time is challenging. Incorporating image mapping convolutional neural networks (CNN)…

Machine Learning · Statistics 2023-08-31 Il Yong Chun , Jeffrey A. Fessler

Objective: Positron Emission Tomography (PET) has been a commonly used imaging modality in broad clinical applications. One of the most important tradeoffs in PET imaging is between image quality and radiation dose: high image quality comes…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Shaoyan Pan , Elham Abouei , Junbo Peng , Joshua Qian , Jacob F Wynne , Tonghe Wang , Chih-Wei Chang , Justin Roper , Jonathon A Nye , Hui Mao , Xiaofeng Yang

Commercial iterative reconstruction techniques on modern CT scanners target radiation dose reduction but there are lingering concerns over their impact on image appearance and low contrast detectability. Recently, machine learning,…

Computer Vision and Pattern Recognition · Computer Science 2019-07-16 Hongming Shan , Atul Padole , Fatemeh Homayounieh , Uwe Kruger , Ruhani Doda Khera , Chayanin Nitiwarangkul , Mannudeep K. Kalra , Ge Wang

While filtered back projection (FBP) is still the method of choice for fast tomographic reconstruction, its performance degrades noticeably in the presence of noise, incomplete sampling, or non-standard scan geometries. We propose a…

Numerical Analysis · Mathematics 2026-02-16 Hamid Fathi , Alexander Skorikov , Tristan van Leeuwen

X-ray computed tomography (CT) reconstructs cross-sectional images from projection data. However, ionizing X-ray radiation associated with CT scanning might induce cancer and genetic damage. Therefore, the reduction of radiation dose has…

Image and Video Processing · Electrical Eng. & Systems 2019-09-13 Huidong Xie , Hongming Shan , Wenxiang Cong , Xiaohua Zhang , Shaohua Liu , Ruola Ning , Ge Wang

In this paper, we first propose a variational model for the limited-angle computed tomography (CT) image reconstruction and then convert the model into an end-to-end deep network.We use the penalty method to solve the model and divide it…

Image and Video Processing · Electrical Eng. & Systems 2020-08-11 Wei Wang , Xiang-Gen Xia , Chuanjiang He , Zemin Ren , Jian Lu , Tianfu Wang , Baiying Lei

An image or volume of interest in positron emission tomography (PET) is reconstructed from pairs of gamma rays emitted from a radioactive substance. Many image reconstruction methods are based on estimation of pixels or voxels on some…

Signal Processing · Electrical Eng. & Systems 2019-06-18 Azra Tafro , Damir Seršić , Ana Sović Kržić

X-ray imaging, based on penetration, enables detailed visualization of internal structures. Building on this capability, existing implicit 3D reconstruction methods have adapted the NeRF model and its variants for internal CT…

Computer Vision and Pattern Recognition · Computer Science 2025-12-18 Qinglei Cao , Ziyao Tang , Xiaoqin Tang

Positron Emission Tomography (PET) is an important clinical imaging tool but inevitably introduces radiation hazards to patients and healthcare providers. Reducing the tracer injection dose and eliminating the CT acquisition for attenuation…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Tianqi Chen , Jun Hou , Yinchi Zhou , Huidong Xie , Xiongchao Chen , Qiong Liu , Xueqi Guo , Menghua Xia , James S. Duncan , Chi Liu , Bo Zhou

Sparse-view Computed Tomography (CT) is an emerging protocol designed to reduce X-ray dose radiation in medical imaging. Traditional Filtered Back Projection algorithm reconstructions suffer from severe artifacts due to sparse data. In…

Numerical Analysis · Mathematics 2024-12-03 Elena Loli Piccolomini , Davide Evangelista , Elena Morotti

In computed tomography (CT), the forward model consists of a linear Radon transform followed by an exponential nonlinearity based on the attenuation of light according to the Beer-Lambert Law. Conventional reconstruction often involves…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Sara Fridovich-Keil , Fabrizio Valdivia , Gordon Wetzstein , Benjamin Recht , Mahdi Soltanolkotabi

Digital holography enables us to reconstruct objects in three-dimensional space from holograms captured by an imaging device. For the reconstruction, we need to know the depth position of the recoded object in advance. In this study, we…

Computer Vision and Pattern Recognition · Computer Science 2018-02-05 Tomoyoshi Shimobaba , Takashi Kakue , Tomoyoshi Ito

Positron Emission Tomography and Magnetic Resonance Imaging (PET-MRI) systems can obtain functional and anatomical scans. PET suffers from a low signal-to-noise ratio. Meanwhile, the k-space data acquisition process in MRI is…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Taofeng Xie , Zhuo-Xu Cui , Chen Luo , Huayu Wang , Congcong Liu , Yuanzhi Zhang , Xuemei Wang , Yanjie Zhu , Guoqing Chen , Dong Liang , Qiyu Jin , Yihang Zhou , Haifeng Wang

In this paper, we propose a sinogram inpainting network (SIN) to solve limited-angle CT reconstruction problem, which is a very challenging ill-posed issue and of great interest for several clinical applications. A common approach to the…

Medical Physics · Physics 2018-11-12 Ji Zhao , Zhiqiang Chen , Li Zhang , Xin Jin

4D time-space reconstruction of dynamic events or deforming objects using X-ray computed tomography (CT) is an important inverse problem in non-destructive evaluation. Conventional back-projection based reconstruction methods assume that…

Image and Video Processing · Electrical Eng. & Systems 2025-02-27 K. Aditya Mohan , Massimiliano Ferrucci , Chuck Divin , Garrett A. Stevenson , Hyojin Kim

Regularization methods are commonly used in X-ray CT image reconstruction. Different regularization methods reflect the characterization of different prior knowledge of images. In a recent work, a new regularization method called a…

Medical Physics · Physics 2017-04-18 Wenxiang Cong , Ge Wang , Qingsong Yang , Jiang Hsieh , Jia Li , Rongjie Lai