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In this paper, we review physics- and data-driven reconstruction techniques for simultaneous positron emission tomography (PET) / magnetic resonance imaging (MRI) systems, which have significant advantages for clinical imaging of cancer,…

Image and Video Processing · Electrical Eng. & Systems 2022-06-15 Abhejit Rajagopal , Andrew P. Leynes , Nicholas Dwork , Jessica E. Scholey , Thomas A. Hope , Peder E. Z. Larson

Recent work has shown improved lesion detectability and flexibility to reconstruction hyperparameters (e.g. scanner geometry or dose level) when PET images are reconstructed by leveraging pre-trained diffusion models. Such methods train a…

Medical Physics · Physics 2025-08-28 George Webber , Alexander Hammers , Andrew P. King , Andrew J. Reader

For conventional computed tomography (CT) image reconstruction tasks, the most popular method is the so-called filtered-back-projection (FBP) algorithm. In it, the acquired Radon projections are usually filtered first by a ramp kernel…

Medical Physics · Physics 2018-07-06 Yongshuai Ge , Qiyang Zhang , Zhanli Hu , Jianwei Chen , Wei Shi , Hairong Zheng , Dong Liang

In this paper, we explore a novel method for tomographic image reconstruction in the field of SPECT imaging. Deep Learning methodologies and more specifically deep convolutional neural networks (CNN) are employed in the new reconstruction…

Machine Learning · Computer Science 2020-10-20 Charalambos Chrysostomou , Loizos Koutsantonis , Christos Lemesios , Costas N. Papanicolas

Deep neural networks are a very powerful tool for many computer vision tasks, including image restoration, exhibiting state-of-the-art results. However, the performance of deep learning methods tends to drop once the observation model used…

Image and Video Processing · Electrical Eng. & Systems 2020-07-01 Jenny Zukerman , Tom Tirer , Raja Giryes

Patlak model is widely used in 18F-FDG dynamic positron emission tomography (PET) imaging, where the estimated parametric images reveal important biochemical and physiology information. Because of better noise modeling and more information…

Medical Physics · Physics 2020-09-15 Nuobei Xie , Kuang Gong , Ning Guo , Zhixing Qin , Jianan Cui , Zhifang Wu , Huafeng Liu , Quanzheng Li

Deep learning-based reconstruction of positron emission tomography(PET) data has gained increasing attention in recent years. While these methods achieve fast reconstruction,concerns remain regarding quantitative accuracy and the presence…

Positron emission tomography (PET) is an important functional medical imaging technique often used in the evaluation of certain brain disorders, whose reconstruction problem is ill-posed. The vast majority of reconstruction methods in PET…

Image and Video Processing · Electrical Eng. & Systems 2023-06-09 Tin Vlašić , Tomislav Matulić , Damir Seršić

Anatomically guided PET reconstruction using MRI information has been shown to have the potential to improve PET image quality. However, these improvements are limited to PET scans with paired MRI information. In this work we employed a…

Image and Video Processing · Electrical Eng. & Systems 2024-03-28 Weijie Gan , Huidong Xie , Carl von Gall , Günther Platsch , Michael T. Jurkiewicz , Andrea Andrade , Udunna C. Anazodo , Ulugbek S. Kamilov , Hongyu An , Jorge Cabello

In this paper, we present a novel method for tomographic image reconstruction in SPECT imaging with a low number of projections. Deep convolutional neural networks (CNN) are employed in the new reconstruction method. Projection data from…

Artificial Intelligence · Computer Science 2021-08-10 Charalambos Chrysostomou , Loizos Koutsantonis , Christos Lemesios , Costas N. Papanicolas

Positron emission tomography (PET) reconstruction has become an ill-posed inverse problem due to low-count projection data, and a robust algorithm is urgently required to improve imaging quality. Recently, the deep image prior (DIP) has…

Image and Video Processing · Electrical Eng. & Systems 2021-11-01 Chenyu Shen , Wenjun Xia , Hongwei Ye , Mingzheng Hou , Hu Chen , Yan Liu , Jiliu Zhou , Yi Zhang

Although supervised convolutional neural networks (CNNs) often outperform conventional alternatives for denoising positron emission tomography (PET) images, they require many low- and high-quality reference PET image pairs. Herein, we…

Medical Physics · Physics 2021-09-29 Yuya Onishi , Fumio Hashimoto , Kibo Ote , Hiroyuki Ohba , Ryosuke Ota , Etsuji Yoshikawa , Yasuomi Ouchi

Large high-quality medical image datasets are difficult to acquire but necessary for many deep learning applications. For positron emission tomography (PET), reconstructed image quality is limited by inherent Poisson noise. We propose a…

Positron emission tomography(PET) image reconstruction is an ill-posed inverse problem and suffers from high level of noise due to limited counts received. Recently deep neural networks especially convolutional neural networks(CNN) have…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Rui Hu , Huafeng Liu

Dynamic positron emission tomography (dPET) image reconstruction is extremely challenging due to the limited counts received in individual frame. In this paper, we propose a spatial-temporal convolutional primal dual network (STPDnet) for…

Image and Video Processing · Electrical Eng. & Systems 2023-03-09 Rui Hu , Jianan Cui , Chengjin Yu , Yunmei Chen , Huafeng Liu

We investigate subset-based optimization methods for positron emission tomography (PET) image reconstruction incorporating a regularizing prior. PET reconstruction methods that use a prior, such as the relative difference prior (RDP), are…

Medical Physics · Physics 2025-06-06 Matthias J. Ehrhardt , Zeljko Kereta , Georg Schramm

Deep learning has significantly advanced PET image re-construction, achieving remarkable improvements in image quality through direct training on sinogram or image data. Traditional methods often utilize masks for inpainting tasks, but…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Bin Huang , Binzhong He , Yanhan Chen , Zhili Liu , Xinyue Wang , Binxuan Li , Qiegen Liu

Differentiable rendering has been widely adopted in computer graphics as a powerful approach to inverse problems, enabling efficient gradient-based optimization by differentiating the image formation process with respect to millions of…

Deep-neural-network-based image reconstruction has demonstrated promising performance in medical imaging for under-sampled and low-dose scenarios. However, it requires large amount of memory and extensive time for the training. It is…

Computer Vision and Pattern Recognition · Computer Science 2019-06-12 Dufan Wu , Kyungsang Kim , Quanzheng Li

Historically, patient datasets have been used to develop and validate various reconstruction algorithms for PET/MRI and PET/CT. To enable such algorithm development, without the need for acquiring hundreds of patient exams, in this paper we…