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Online Controlled Experiments (OCEs) are the gold standard in evaluating the effectiveness of changes to websites. An important type of OCE evaluates different personalization strategies, which present challenges in low test power and lack…

Methodology · Statistics 2023-05-11 C. H. Bryan Liu , Emma J. McCoy

Accurate estimation of treatment effects in online A/B testing is challenging with zero-inflated and skewed metrics. Traditional tests, like Welch's t-test, often lack sensitivity with heavy-tailed data due to their reliance on means, as…

Methodology · Statistics 2025-10-07 Kevin Charette , Tristan Boudreault

When a subgroup is identified from the data, it must be evaluated in a replicable way. The usual in-sample approach, which evaluates the post-hoc identified subgroup as predefined, might suffer from selection bias. This issue of in-sample…

Methodology · Statistics 2026-05-06 Shuoxun Xu , Xinzhou Guo

In biomedical Subgroup Discovery, practitioners are interested in discovering interpretable and homogeneous subgroups within a group of patients. In this paper, assuming that healthy subjects (i.e., controls) share common but irrelevant…

Machine Learning · Computer Science 2026-05-21 Robin Louiset , Edouard Duchesnay , Benoit Dufumier , Antoine Grigis , Pietro Gori

The primary benefit of identifying a valid surrogate marker is the ability to use it in a future trial to test for a treatment effect with shorter follow-up time or less cost. However, previous work has demonstrated potential heterogeneity…

Methodology · Statistics 2022-09-20 Layla Parast , Tianxi Cai , Lu Tian

Triple difference designs have become increasingly popular in empirical economics. The advantage of a triple difference design is that, within a treatment group, it allows for another subgroup of the population -- potentially less impacted…

Econometrics · Economics 2025-06-04 Laura Caron

Wearable sensor systems have demonstrated a great potential for real-time, objective monitoring of physiological health to support behavioral interventions. However, obtaining accurate labels in free-living environments remains difficult…

Many modern tech companies, such as Google, Uber, and Didi, utilize online experiments (also known as A/B testing) to evaluate new policies against existing ones. While most studies concentrate on average treatment effects, situations with…

Methodology · Statistics 2023-05-18 Ting Li , Chengchun Shi , Zhaohua Lu , Yi Li , Hongtu Zhu

Understanding treatment heterogeneity is essential to the development of precision medicine, which seeks to tailor medical treatments to subgroups of patients with similar characteristics. One of the challenges to achieve this goal is that…

Methodology · Statistics 2019-08-21 Shujie Ma , Jian Huang , Zhiwei Zhang , Mingming Liu

The estimation of the treatment effect is often biased in the presence of unobserved confounding variables which are commonly referred to as hidden variables. Although a few methods have been recently proposed to handle the effect of hidden…

Methodology · Statistics 2022-08-01 Kevin Jiang , Yang Ning

Online controlled experiments (A/B tests) have become the gold standard for learning the impact of new product features in technology companies. Randomization enables the inference of causality from an A/B test. The randomized assignment…

Applications · Statistics 2022-12-20 Qike Li , Samir Jamkhande , Pavel Kochetkov , Pai Liu

Subgroup analysis evaluates treatment effects across multiple sub-populations. When subgroups are defined by latent memberships inferred from imperfect measurements, the analysis typically involves two inter-connected models, a latent class…

Methodology · Statistics 2026-01-05 Yuanhui Luo , Xinzhou Guo , Yuqi Gu

In regression and causal inference, controlled subgroup selection aims to identify, with inferential guarantees, a subgroup (defined as a subset of the covariate space) on which the average response or treatment effect is above a given…

Methodology · Statistics 2025-10-31 Nathan Cheng , Asher Spector , Lucas Janson

Estimating the causal effect of a treatment or exposure for a subpopulation is of great interest in many biomedical and economical studies. Expected shortfall, also referred to as the super-quantile, is an attractive effect-size measure…

Methodology · Statistics 2023-03-23 Bo Wei , Kean Ming Tan , Xuming He

A/B testing remains the gold standard for evaluating modifications to e-commerce storefronts, yet it diverts traffic, requires weeks to reach statistical significance, and risks degrading user experience. We present SimGym, a framework for…

Heavy-tailed metrics are common and often critical to product evaluation in the online world. While we may have samples large enough for Central Limit Theorem to kick in, experimentation is challenging due to the wide confidence interval of…

Applications · Statistics 2019-05-23 Jason , Wang , Pauline Burke

The group testing problem consists of determining a small set of defective items from a larger set of items based on a number of possibly-noisy tests, and has numerous practical applications. One of the defining features of group testing is…

Information Theory · Computer Science 2021-11-12 Bernard Teo , Jonathan Scarlett

Treatment effect heterogeneity occurs when individual characteristics influence the effect of a treatment. We propose a novel approach that combines prognostic score matching and conditional inference trees to characterize effect…

The rapid rise of online social networks underscores the need to understand the heterogeneous strengths of online relationships. Yet, efforts to assess tie strength (TS) are hindered by the lack of ground-truth labels, differing research…

Social and Information Networks · Computer Science 2025-06-10 Xueqi Cheng , Catherine Yang , Yuying Zhao , Yu Wang , Hamid Karimi , Tyler Derr

Clinical trials are typically run in order to understand the effects of a new treatment on a given population of patients. However, patients in large populations rarely respond the same way to the same treatment. This heterogeneity in…

Machine Learning · Statistics 2024-02-12 Alihan Hüyük , Zhaozhi Qian , Mihaela van der Schaar