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Recent advances in artificial intelligence, particularly large language models LLMs, have shown promising capabilities in transforming rare disease research. This survey paper explores the integration of LLMs in the analysis of rare…

Computation and Language · Computer Science 2025-05-26 Valentina Carbonari , Pierangelo Veltri , Pietro Hiram Guzzi

Bipolar disorder is a chronic mental illness frequently underdiagnosed due to subtle early symptoms and social stigma. This paper explores the advanced natural language processing (NLP) models for recognizing signs of bipolar disorder based…

Computation and Language · Computer Science 2025-07-22 Khalid Hasan , Jamil Saquer

The rising rate of drug-related deaths in the United States, largely driven by fentanyl, requires timely and accurate surveillance. However, critical overdose data are often buried in free-text coroner reports, leading to delays and…

Natural language processing (NLP) is becoming an important means for automatic recognition of human traits and states, such as intoxication, presence of psychiatric disorders, presence of airway disorders and states of stress. Such…

Computation and Language · Computer Science 2021-06-03 Joppe Wouts , Janna de Boer , Alban Voppel , Sanne Brederoo , Sander van Splunter , Iris Sommer

Recent years have witnessed a substantial increase in the use of deep learning to solve various natural language processing (NLP) problems. Early deep learning models were constrained by their sequential or unidirectional nature, such that…

Information Retrieval · Computer Science 2024-03-05 Jiajia Wang , Jimmy X. Huang , Xinhui Tu , Junmei Wang , Angela J. Huang , Md Tahmid Rahman Laskar , Amran Bhuiyan

Depression is a widespread mental health issue, affecting an estimated 3.8% of the global population. It is also one of the main contributors to disability worldwide. Recently it is becoming popular for individuals to use social media…

Computation and Language · Computer Science 2024-03-21 Ziyi Chen , Ren Yang , Sunyang Fu , Nansu Zong , Hongfang Liu , Ming Huang

Clinical Named Entity Recognition (CNER) aims to identify and classify clinical terms such as diseases, symptoms, treatments, exams, and body parts in electronic health records, which is a fundamental and crucial task for clinical and…

Computation and Language · Computer Science 2018-04-16 Qi Wang , Yuhang Xia , Yangming Zhou , Tong Ruan , Daqi Gao , Ping He

Biomedical Named Entity Recognition (NER) is a fundamental task of Biomedical Natural Language Processing for extracting relevant information from biomedical texts, such as clinical records, scientific publications, and electronic health…

Computation and Language · Computer Science 2023-12-27 Fahime Shahrokh , Nasser Ghadiri , Rasoul Samani , Milad Moradi

Pretraining deep language models has led to large performance gains in NLP. Despite this success, Schick and Sch\"utze (2020) recently showed that these models struggle to understand rare words. For static word embeddings, this problem has…

Computation and Language · Computer Science 2020-04-30 Timo Schick , Hinrich Schütze

Since no effective therapies exist for Alzheimer's disease (AD), prevention has become more critical through lifestyle factor changes and interventions. Analyzing electronic health records (EHR) of patients with AD can help us better…

Computation and Language · Computer Science 2021-01-26 Zitao Shen , Yoonkwon Yi , Anusha Bompelli , Fang Yu , Yanshan Wang , Rui Zhang

Machine learning methods have recently achieved high-performance in biomedical text analysis. However, a major bottleneck in the widespread application of these methods is obtaining the required large amounts of annotated training data,…

Machine Learning · Computer Science 2019-12-06 Xing Meng , Craig H. Ganoe , Ryan T. Sieberg , Yvonne Y. Cheung , Saeed Hassanpour

Rare diseases affect over 300 million people worldwide and are characterized by complex care pathways, limited clinical expertise, and substantial unmet communication needs throughout the long patient journey. Recent advances in large…

Computation and Language · Computer Science 2026-04-17 Zaifu Zhan , Yu Hou , Kai Yu , Min Zeng , Anita Burgun , Xiaoyi Chen , Rui Zhang

Initial fault detection and diagnostics are imperative measures to improve the efficiency, safety, and stability of vehicle operation. In recent years, numerous studies have investigated data-driven approaches to improve the vehicle…

Systems and Control · Electrical Eng. & Systems 2021-12-01 Ali Khodadadi , Soroush Ghandiparsi , Chen-Nee Chuah

Rare diseases have extremely low-data regimes, unlike common diseases with large amount of available labeled data. Hence, to train a neural network to classify rare diseases with a few per-class data samples is very challenging, and so far,…

Computer Vision and Pattern Recognition · Computer Science 2020-07-16 Xiaomeng Li , Lequan Yu , Yueming Jin , Chi-Wing Fu , Lei Xing , Pheng-Ann Heng

Despite the impressive capabilities of Large Language Models (LLMs) in general medical domains, questions remain about their performance in diagnosing rare diseases. To answer this question, we aim to assess the diagnostic performance of…

Computational Engineering, Finance, and Science · Computer Science 2024-08-19 Guanchu Wang , Junhao Ran , Ruixiang Tang , Chia-Yuan Chang , Chia-Yuan Chang , Yu-Neng Chuang , Zirui Liu , Vladimir Braverman , Zhandong Liu , Xia Hu

Developing high-performance entity normalization algorithms that can alleviate the term variation problem is of great interest to the biomedical community. Although deep learning-based methods have been successfully applied to biomedical…

Information Retrieval · Computer Science 2019-08-12 Zongcheng Ji , Qiang Wei , Hua Xu

Healthcare domain generates a lot of unstructured and semi-structured text. Natural Language processing (NLP) has been used extensively to process this data. Deep Learning based NLP especially Large Language Models (LLMs) such as BERT have…

Computation and Language · Computer Science 2023-01-11 Kunal Suri , Atul Singh , Prakhar Mishra , Swapna Sourav Rout , Rajesh Sabapathy

Recent advances in natural language processing (NLP) can be largely attributed to the advent of pre-trained language models such as BERT and RoBERTa. While these models demonstrate remarkable performance on general datasets, they can…

Natural Language Processing (NLP) techniques can be applied to help with the diagnosis of medical conditions such as depression, using a collection of a person's utterances. Depression is a serious medical illness that can have adverse…

Computation and Language · Computer Science 2022-06-17 Priyam Basu , Tiasa Singha Roy , Rakshit Naidu , Zumrut Muftuoglu , Sahib Singh , Fatemehsadat Mireshghallah

Dementia is a neurodegenerative disorder that causes cognitive decline and affects more than 50 million people worldwide. Dementia is under-diagnosed by healthcare professionals - only one in four people who suffer from dementia are…