Related papers: Regulatory Feedback Effects on Tissue Growth Dynam…
For cellular biochemical reaction systems where the numbers of molecules is small, significant noise is associated with chemical reaction events. This molecular noise can give rise to behavior that is very different from the predictions of…
For channel flow at subcritical Reynolds numbers ($Re<5772$), a laminar-to-turbulent transition can emerge due to a large transient amplification in the kinetic energy of small perturbations, resulting in an increase in drag at the walls.…
We present a model for continuous cell culture coupling intra-cellular metabolism to extracellular variables describing the state of the bioreactor, taking into account the growth capacity of the cell and the impact of toxic byproduct…
Growth (and resorption) of biological tissue is formulated in the continuum setting. The treatment is macroscopic, rather than cellular or sub-cellular. Certain assumptions that are central to classical continuum mechanics are revisited,…
A macroscopic theory for describing cellular states during steady-growth is presented, which is based on the consistency between cellular growth and molecular replication, as well as the robustness of phenotypes against perturbations.…
A one-dimensional cellular automaton with a probabilistic evolution rule can generate stochastic surface growth in $(1 + 1)$ dimensions. Two such discrete models of surface growth are constructed from a probabilistic cellular automaton…
Synapses change on multiple timescales, ranging from milliseconds to minutes, due to a combination of both short- and long-term plasticity. Here we develop an extension of the common Generalized Linear Model to infer both short- and…
The feedback between mechanical and chemical signals plays a key role in controlling many biological processes and collective cell behavior. Here we focus on the emergence of spatiotemporal density waves in a one-dimensional "cell train."…
We investigate the coherence and steady-state properties of the Jaynes-Cummings model subjected to time-delayed coherent feedback in the regime of multiple excitations. The introduced feedback qualitatively modifies the dynamical response…
When bacteria are grown on a mixture of two growth-limiting substrates, they exhibit a rich spectrum of substrate consumption patterns including diauxic growth, simultaneous consumption, and bistable growth. In previous work, we showed that…
Eukaryotic cells can move spontaneously without being guided by external cues. For such spontaneous movements, a variety of different modes have been observed, including the amoeboid-like locomotion with protrusion of multiple pseudopods,…
In this study, we explore a mathematical model for tissue growth focusing on the interplay between multiple cell subpopulations with distinct phenotypic characteristics. The model addresses the dynamics of tissue growth influenced by…
A theoretical framework is developed for a precise control of spatial patterns in oscillatory media using nonlinear global feedback, where a proper form of the feedback function corresponding to a specific pattern is predicted through the…
In this technical note we calculate the dynamics of a linear feedback model of progression in the cell cycle in the case that the cells are organized into k=3 clusters. We examine the dynamics in detail for a specific subset of parameters…
Plants are a paradigm for active shape control in response to stimuli. For instance, it is well-known that a tilted plant will eventually straighten vertically, demonstrating the influence of both an external stimulus, gravity, and an…
Control of generically scale-invariant systems, i.e., targeting specific cooperative features in non-linear stochastic interacting systems with many degrees of freedom subject to strong fluctuations and correlations that are characterized…
In this paper, we present a state-feedback controller design method for bilinear systems. To this end, we write the bilinear system as a linear fractional representation by interpreting the state in the bilinearity as a structured…
Feedback loops are major components of biochemical systems. Many systems show multiple such (positive or negative) feedback loops. Nevertheless, very few quantitative analyses address the question how such multiple feedback loops evolved.…
This paper discusses the systematic design of an adaptive feedback linearizing neurocontroller for a high-order model of the synchronous machine/infinite bus power system. The power system is first modelled as an input-output nonlinear…
In stochastic multistable systems driven by the gradient of a potential, transitions between equilibria is possible because of noise. We study the ability of linear delay feedback control to mitigate these transitions, ensuring that the…