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We consider the classical $k$-Center problem in undirected graphs. The problem is known to have a polynomial-time 2-approximation. There are even $(2+\varepsilon)$-approximations running in near-linear time. The conventional wisdom is that…

Data Structures and Algorithms · Computer Science 2025-03-13 Ce Jin , Yael Kirkpatrick , Virginia Vassilevska Williams , Nicole Wein

Estimating parameters of dynamic models from experimental data is a challenging, and often computationally-demanding task. It requires a large number of model simulations and objective function gradient computations, if gradient-based…

Quantitative Methods · Quantitative Biology 2024-05-28 Polina Lakrisenko , Dilan Pathirana , Daniel Weindl , Jan Hasenauer

A random walk-based method is proposed to efficiently compute the solution of a large class of fractional in time linear systems of differential equations (linear F-ODE systems), along with the derivatives with respect to the system…

Numerical Analysis · Mathematics 2024-08-09 Andrés Centeno , Juan A. Acebrón , José Monteiro

We propose a finite-dimensional control-based method to approximate solution operators for evolutional partial differential equations (PDEs), particularly in high-dimensions. By employing a general reduced-order model, such as a deep neural…

Numerical Analysis · Mathematics 2024-01-22 Nathan Gaby , Xiaojing Ye

We examine directed spanners through flow-based linear programming relaxations. We design an $\~O(n^{2/3})$-approximation algorithm for the directed $k$-spanner problem that works for all $k\geq 1$, which is the first sublinear…

Data Structures and Algorithms · Computer Science 2010-11-23 Michael Dinitz , Robert Krauthgamer

We address the problem of Bayesian inference for parameters in ordinary differential equation (ODE) models based on observational data. Conventional approaches in this setting typically rely on numerical solvers such as the Euler or…

Methodology · Statistics 2025-12-01 Shoji Toyota , Yuto Miyatake

Neural Ordinary Differential Equations (NODEs) use a neural network to model the instantaneous rate of change in the state of a system. However, despite their apparent suitability for dynamics-governed time-series, NODEs present a few…

Machine Learning · Computer Science 2021-08-18 Alexander Norcliffe , Cristian Bodnar , Ben Day , Jacob Moss , Pietro Liò

We develop a Bayesian inference method for discretely-observed stochastic differential equations (SDEs). Inference is challenging for most SDEs, due to the analytical intractability of the likelihood function. Nevertheless, forward…

Methodology · Statistics 2024-11-08 Petar Jovanovski , Andrew Golightly , Umberto Picchini

In this work, we study the maximum matching problem from the perspective of sensitivity. The sensitivity of an algorithm $A$ on a graph $G$ is defined as the maximum Wasserstein distance between the output distributions of $A$ on $G$ and on…

Data Structures and Algorithms · Computer Science 2025-11-24 Yuichi Yoshida , Zihan Zhang

Reachability analysis is a fundamental problem for safety verification and falsification of Cyber-Physical Systems (CPS) whose dynamics follow physical laws usually represented as differential equations. In the last two decades, numerous…

Symbolic Computation · Computer Science 2018-04-11 Hoang-Dung Tran , Weiming Xiang , Nathaniel Hamilton , Taylor T. Johnson

We improve the running time of the general algorithmic technique known as Baker's approach (1994) on H-minor-free graphs from O(n^{f(|H|)}) to O(f(|H|) n^{O(1)}). The numerous applications include e.g. a 2-approximation for coloring and…

Data Structures and Algorithms · Computer Science 2015-05-18 Siamak Tazari

We consider parameter estimation of ordinary differential equation (ODE) models from noisy observations. For this problem, one conventional approach is to fit numerical solutions (e.g., Euler, Runge--Kutta) of ODEs to data. However, such a…

Methodology · Statistics 2021-09-01 Takeru Matsuda , Yuto Miyatake

Algebraic techniques have had an important impact on graph algorithms so far. Porting them, e.g., the matrix inverse, into the dynamic regime improved best-known bounds for various dynamic graph problems. In this paper, we develop new…

Data Structures and Algorithms · Computer Science 2023-08-21 Adam Karczmarz , Piotr Sankowski

We present a new approach for estimating parameters in rational ODE models from given (measured) time series data. In typical existing approaches, an initial guess for the parameter values is made from a given search interval. Then, in a…

Mathematical Software · Computer Science 2023-12-19 Oren Bassik , Yosef Berman , Soo Go , Hoon Hong , Ilia Ilmer , Alexey Ovchinnikov , Chris Rackauckas , Pedro Soto , Chee Yap

In the modelling of stochastic phenomena, such as quasi-reaction systems, parameter estimation of kinetic rates can be challenging, particularly when the time gap between consecutive measurements is large. Local linear approximation…

Methodology · Statistics 2026-03-10 Matteo Framba , Veronica Vinciotti , Ernst C. Wit

Ordinary differential equations (ODE's) are widespread models in physics, chemistry and biology. In particular, this mathematical formalism is used for describing the evolution of complex systems and it might consist of high-dimensional…

Statistics Theory · Mathematics 2008-12-22 Nicolas J-B. Brunel

Pseudospectral approximation provides a means to approximate the dynamics of delay differential equations (DDE) by ordinary differential equations (ODE). This article develops a computer-aided algorithm to determine the distance between the…

Dynamical Systems · Mathematics 2024-05-14 Shane Kepley , Babette A. J. de Wolff

In the sensitive distance oracle problem, there are three phases. We first preprocess a given directed graph $G$ with $n$ nodes and integer weights from $[-W,W]$. Second, given a single batch of $f$ edge insertions and deletions, we update…

Data Structures and Algorithms · Computer Science 2019-07-23 Jan van den Brand , Thatchaphol Saranurak

Inverse problem for the identification of the parameters for large-scale systems of nonlinear ordinary differential equations (ODEs) arising in systems biology is analyzed. In a recent paper in \textit{Mathematical Biosciences, 305(2018),…

Quantitative Methods · Quantitative Biology 2020-12-07 Ugur G. Abdulla , Roby Poteau

We continue the study of distance sensitivity oracles (DSOs). Given a directed graph $G$ with $n$ vertices and edge weights in $\{1, 2, \dots, M\}$, we want to build a data structure such that given any source vertex $u$, any target vertex…

Data Structures and Algorithms · Computer Science 2021-08-04 Yong Gu , Hanlin Ren