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We present a novel neural network architecture, US-Net, for robust nuclei instance segmentation in histopathology images. The proposed framework integrates the nuclei detection and segmentation networks by sharing their outputs through the…

Computer Vision and Pattern Recognition · Computer Science 2019-02-04 Zhaoyang Xu , Faranak Sobhani , Carlos Fernandez Moro , Qianni Zhang

Automatic segmentation of organs-at-risk (OAR) in computed tomography (CT) is an essential part of planning effective treatment strategies to combat lung and esophageal cancer. Accurate segmentation of organs surrounding tumours helps…

Computer Vision and Pattern Recognition · Computer Science 2019-05-21 Sulaiman Vesal , Nishant Ravikumar , Andreas Maier

Incorporating human domain knowledge for breast tumor diagnosis is challenging, since shape, boundary, curvature, intensity, or other common medical priors vary significantly across patients and cannot be employed. This work proposes a new…

Image and Video Processing · Electrical Eng. & Systems 2020-09-03 Aleksandar Vakanski , Min Xian , Phoebe Freer

Deep cerebellar nuclei are a key structure of the cerebellum that are involved in processing motor and sensory information. It is thus a crucial step to accurately segment deep cerebellar nuclei for the understanding of the cerebellum…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Jinyoung Kim , Remi Patriat , Jordan Kaplan , Oren Solomon , Noam Harel

Pancreatic cancer will soon be the second leading cause of cancer-related death in Western society. Imaging techniques such as CT, MRI and ultrasound typically help providing the initial diagnosis, but histopathological assessment is still…

Image and Video Processing · Electrical Eng. & Systems 2022-01-26 Pierpaolo Vendittelli , Esther M. M. Smeets , Geert Litjens

Oral cancer is a significant global health burden, and early detection remains a critical clinical need. Electrical impedance spectroscopy (EIS) offers a promising non-invasive approach for real-time tissue characterization, but…

Early detection of cancer can help improve patient prognosis by early intervention. Head and neck cancer is diagnosed in specialist centres after a surgical biopsy, however, there is a potential for these to be missed leading to delayed…

Computer Vision and Pattern Recognition · Computer Science 2024-05-08 Abdullah Alsalemi , Anza Shakeel , Mollie Clark , Syed Ali Khurram , Shan E Ahmed Raza

Due to the wide existence and large morphological variances of nuclei, accurate nuclei instance segmentation is still one of the most challenging tasks in computational pathology. The annotating of nuclei instances, requiring experienced…

Computer Vision and Pattern Recognition · Computer Science 2020-07-23 Xinpeng Xie , Jiawei Chen , Yuexiang Li , Linlin Shen , Kai Ma , Yefeng Zheng

Accurate segmentation of gastrointestinal (GI) organs in magnetic resonance enterography (MRE) is critical for diagnosing inflammatory bowel disease (IBD). However, anatomical variability, class imbalance, and low tissue contrast hinder…

Image and Video Processing · Electrical Eng. & Systems 2026-04-21 Ashiqur Rahman , Md. Abu Sayed , Md Sharjis Ibne Wadud , Md. Abu Asad Al-Hafiz , Adam Mushtak , Muhammad E. H. Chowdhury

Liver cancer is one of the leading causes of cancer death. To assist doctors in hepatocellular carcinoma diagnosis and treatment planning, an accurate and automatic liver and tumor segmentation method is highly demanded in the clinical…

Computer Vision and Pattern Recognition · Computer Science 2018-07-04 Xiaomeng Li , Hao Chen , Xiaojuan Qi , Qi Dou , Chi-Wing Fu , Pheng Ann Heng

Automatic tumor or lesion segmentation is a crucial step in medical image analysis for computer-aided diagnosis. Although the existing methods based on Convolutional Neural Networks (CNNs) have achieved the state-of-the-art performance,…

Image and Video Processing · Electrical Eng. & Systems 2022-08-01 Shuchao Pang , Anan Du , Mehmet A. Orgun , Yan Wang , Quan Z. Sheng , Shoujin Wang , Xiaoshui Huang , Zhenmei Yu

Accurate nuclei detection and classification are fundamental to computational pathology, yet existing approaches are hindered by reliance on detailed expert annotations and insufficient use of tissue context. We present Tissue-Aware Nuclei…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Kesi Xu , Eleni Chiou , Ali Varamesh , Laura Acqualagna , Nasir Rajpoot

Lung cancer is an extremely lethal disease primarily due to its late-stage diagnosis and significant mortality rate, making it the major cause of cancer-related demises globally. Machine Learning (ML) and Convolution Neural network (CNN)…

Image and Video Processing · Electrical Eng. & Systems 2025-01-03 Asha V , Bhavanishankar K

Segmentation of regions of interest in images of patients, is a crucial step in many medical procedures. Deep neural networks have proven to be particularly adept at this task. However, a key question is what type of deep neural network to…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Vangelis Kostoulas , Peter A. N. Bosman , Tanja Alderliesten

Accurate segmentation and classification of nuclei in histology images is critical but challenging due to nuclei heterogeneity, staining variations, and tissue complexity. Existing methods often struggle with limited dataset variability,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Wenhua Zhang , Sen Yang , Meiwei Luo , Chuan He , Yuchen Li , Jun Zhang , Xiyue Wang , Fang Wang

Nucleus image segmentation is a crucial step in the analysis, pathological diagnosis, and classification, which heavily relies on the quality of nucleus segmentation. However, the complexity of issues such as variations in nucleus size,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-11 Junzhou Chen , Qian Huang , Yulin Chen , Linyi Qian , Chengyuan Yu

Optical coherence tomography (OCT) is a medical imaging modality that allows us to probe deeper substructures of skin. The state-of-the-art wound care prediction and monitoring methods are based on visual evaluation and focus on surface…

Image and Video Processing · Electrical Eng. & Systems 2023-06-05 Prashant Kumar , Swatantra Dhara , Ayan Gope , Jyotirmoy Chatterjee , Subhamoy Mandal

Early detection of cancerous tissue is crucial for long-term patient survival. In the head and neck region, a typical diagnostic procedure is an endoscopic intervention where a medical expert manually assesses tissue using RGB camera…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Marcel Bengs , Nils Gessert , Wiebke Laffers , Dennis Eggert , Stephan Westermann , Nina A. Mueller , Andreas O. H. Gerstner , Christian Betz , Alexander Schlaefer

Diabetic retinopathy (DR) is a leading cause of vision loss, requiring early and accurate assessment to prevent irreversible damage. Spectral Domain Optical Coherence Tomography (SD-OCT) enables high-resolution retinal imaging, but…

Image and Video Processing · Electrical Eng. & Systems 2025-07-15 S. Chen , D. Ma , M. Raviselvan , S. Sundaramoorthy , K. Popuri , M. J. Ju , M. V. Sarunic , D. Ratra , M. F. Beg

Accurate medical image segmentation is essential for diagnosis and treatment planning of diseases. Convolutional Neural Networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they are…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Ran Gu , Guotai Wang , Tao Song , Rui Huang , Michael Aertsen , Jan Deprest , Sébastien Ourselin , Tom Vercauteren , Shaoting Zhang
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