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This paper extends the canonical model of epidemiology, SIRD model, to allow for time varying parameters for real-time measurement of the stance of the COVID-19 pandemic. Time variation in model parameters is captured using the generalized…

Populations and Evolution · Quantitative Biology 2021-02-11 Cem Cakmakli , Yasin Simsek

We refine a stimulating study by Sarvotham et al. [2005] which highlighted the influence of peak transmission rate on network burstiness. From TCP packet headers, we amalgamate packets into sessions where each session is characterized by a…

Applications · Statistics 2009-05-14 Luis Lopez-Oliveros , Sidney I. Resnick

The coronavirus pandemic has rapidly evolved into an unprecedented crisis. The susceptible-infectious-removed (SIR) model and its variants have been used for modeling the pandemic. However, time-independent parameters in the classical…

Populations and Evolution · Quantitative Biology 2020-09-09 Hyokyoung G. Hong , Yi Li

Extreme value analysis is an essential methodology in the study of rare and extreme events, which hold significant interest in various fields, particularly in the context of environmental sciences. Models that employ the exceedances of…

Methodology · Statistics 2025-07-16 Lorenzo Dell'Oro , Carlo Gaetan

We demonstrate that the information contained in the spike occurrence times of a population of neurons can be broken up into a series of terms, each of which reflect something about potential coding mechanisms. This is possible in the…

Biological Physics · Physics 2007-05-23 S. Panzeri , S. R. Schultz

A possibly time-dependent transition intensity matrix or generator $(Q(t))$ characterizes the law of a Markov jump process (MP). For a time homogeneous MP, the transition probability matrix (TPM) can be expressed as a matrix exponential of…

Methodology · Statistics 2025-07-23 Dario Gasbarra , Sangita Kulathinal , Etienne Sebag

Robust reinforcement learning is essential for deploying reinforcement learning algorithms in real-world scenarios where environmental uncertainty predominates. Traditional robust reinforcement learning often depends on rectangularity…

Machine Learning · Computer Science 2024-06-13 Adil Zouitine , David Bertoin , Pierre Clavier , Matthieu Geist , Emmanuel Rachelson

The framework of transition state theory (TST) provides a powerful way for analyzing the dynamics of physical and chemical reactions. While TST has already been successfully used to obtain reaction rates for systems with a single…

Chemical Physics · Physics 2021-02-26 Johannes Reiff , Matthias Feldmaier , Jörg Main , Rigoberto Hernandez

The past decade has seen an increasing body of literature devoted to the estimation of causal effects in network-dependent data. However, the validity of many classical statistical methods in such data is often questioned. There is an…

Computation · Statistics 2017-05-31 Oleg Sofrygin , Romain Neugebauer , Mark J. van der Laan

Markov cohort state-transition models have been the standard approach for simulating the prognosis of patients or, more generally, the life trajectories of individuals over a time period. Current approaches for estimating the variance of a…

Applications · Statistics 2022-04-07 Rowan Iskandar , Cassandra Berns

Topological data analysis (TDA) approaches are becoming increasingly popular for studying the dependence patterns in multivariate time series data. In particular, various dependence patterns in brain networks may be linked to specific tasks…

Methodology · Statistics 2025-12-08 Anass El Yaagoubi Bourakna , Moo K. Chung , Hernando Ombao

Scalable probabilistic modeling and prediction in high dimensional multivariate time-series is a challenging problem, particularly for systems with hidden sources of dependence and/or homogeneity. Examples of such problems include dynamic…

Social and Information Networks · Computer Science 2016-06-07 Forough Arabshahi , Furong Huang , Animashree Anandkumar , Carter T. Butts , Sean M. Fitshugh

Reinforcement learning has been applied to many interesting problems such as the famous TD-gammon and the inverted helicopter flight. However, little effort has been put into developing methods to learn policies for complex persistent tasks…

Artificial Intelligence · Computer Science 2016-06-22 Xiao Li , Calin Belta

Spatial-temporal forecasting plays an important role in many real-world applications, such as traffic forecasting, air pollutant forecasting, crowd-flow forecasting, and so on. State-of-the-art spatial-temporal forecasting models take…

Machine Learning · Computer Science 2024-01-22 Xinyu Su , Jianzhong Qi , Egemen Tanin , Yanchuan Chang , Majid Sarvi

The aim of this paper is to establish a causal link between the policies implemented by technology companies and the outcomes they yield within intricate temporal and/or spatial dependent experiments. We propose a novel…

Methodology · Statistics 2023-12-05 Shikai Luo , Ying Yang , Chengchun Shi , Fang Yao , Jieping Ye , Hongtu Zhu

Many problems of practical interest rely on Continuous-time Markov chains~(CTMCs) defined over combinatorial state spaces, rendering the computation of transition probabilities, and hence probabilistic inference, difficult or impossible…

Real-world dynamical systems often consist of multiple stochastic subsystems that interact with each other. Modeling and forecasting the behavior of such dynamics are generally not easy, due to the inherent hardness in understanding the…

Machine Learning · Computer Science 2020-01-14 Fan Yang , Ling Chen , Fan Zhou , Yusong Gao , Wei Cao

In many real-world scenarios, interested variables are often represented as discretized values due to measurement limitations. Applying Conditional Independence (CI) tests directly to such discretized data, however, can lead to incorrect…

Artificial Intelligence · Computer Science 2025-06-11 Boyang Sun , Yu Yao , Xinshuai Dong , Zongfang Liu , Tongliang Liu , Yumou Qiu , Kun Zhang

The analysis of multiple time-to-event outcomes in a randomised controlled clinical trial can be accomplished with exisiting methods. However, depending on the characteristics of the disease under investigation and the circumstances in…

Methodology · Statistics 2026-03-02 Moritz Fabian Danzer , Andreas Faldum , Thorsten Simon , Barbara Hero , Rene Schmidt

Epidemic models are used to analyze the progression or outcome of an epidemic under different control policies like vaccinations, quarantines, lockdowns, use of face-masks, pharmaceutical interventions, etc. When these models accurately…

Quantitative Methods · Quantitative Biology 2022-04-19 Carlos Hernandez-Suarez , Osval Montsinos Lopez , Ramon Solano-Barajas