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We propose a biologically plausible computational model of working memory (WM) implemented by the spiking neuron network (SNN) interacting with a network of astrocytes. SNN is modelled by the synaptically coupled Izhikevich neurons with a…

Mathematical model of spiking neuron network (SNN) supplied by astrocytes is investigated. The astrocytes are specific type of brain cells which are not electrically excitable but inducing chemical modulations of neuronal firing. We…

Neurons and Cognition · Quantitative Biology 2023-12-07 Sergey V. Stasenko , Victor B. Kazantsev

Within the complex neuroarchitecture of the brain, astrocytes play crucial roles in development, structure, and metabolism. These cells regulate neural activity through tripartite synapses, directly impacting cognitive processes such as…

Neural and Evolutionary Computing · Computer Science 2023-12-27 Guobin Shen , Dongcheng Zhao , Yiting Dong , Yang Li , Jindong Li , Kang Sun , Yi Zeng

Understanding the role of astrocytes in brain computation is a nascent challenge, promising immense rewards, in terms of new neurobiological knowledge that can be translated into artificial intelligence. In our ongoing effort to identify…

Neurons and Cognition · Quantitative Biology 2018-07-10 Ioannis Polykretis , Vladimir Ivanov , Konstantinos P. Michmizos

The brain consists not only of neurons but also of non-neuronal cells, including astrocytes. Recent discoveries in neuroscience suggest that astrocytes directly regulate neuronal activity by releasing gliotransmitters such as glutamate. In…

Systems and Control · Electrical Eng. & Systems 2023-08-21 Valentin Würzbauer , Kerstin Lenk , Matin Jafarian

Mammalian brains operate in a very special surrounding: to survive they have to react quickly and effectively to the pool of stimuli patterns previously recognized as danger. Many learning tasks often encountered by living organisms involve…

Biological agents navigate complex environments by combining long-term memory of successful actions with short-term suppression of recently visited locations-a capability that remains difficult to replicate in artificial systems, especially…

In the brain, both neurons and glial cells work in conjunction with each other during information processing. Stimulation of neurons can cause calcium oscillations in astrocytes which in turn can affect neuronal calcium dynamics. The…

Neurons and Cognition · Quantitative Biology 2023-08-16 Bhanu Sharma , Spandan Kumar , Subhendu Ghosh , Vikram Singh

Astrocytes are a ubiquitous and enigmatic type of non-neuronal cell and are found in the brain of all vertebrates. While traditionally viewed as being supportive of neurons, it is increasingly recognized that astrocytes may play a more…

Neurons and Cognition · Quantitative Biology 2023-11-13 Lulu Gong , Fabio Pasqualetti , Thomas Papouin , ShiNung Ching

The neuronal paradigm of studying the brain has left us with limitations in both our understanding of how neurons process information to achieve biological intelligence and how such knowledge may be translated into artificial intelligence…

Neurons and Cognition · Quantitative Biology 2020-05-12 Leo Kozachkov , Konstantinos P. Michmizos

This paper presents an innovative methodology for improving the robustness and computational efficiency of Spiking Neural Networks (SNNs), a critical component in neuromorphic computing. The proposed approach integrates astrocytes, a type…

Neural and Evolutionary Computing · Computer Science 2023-09-18 Murat Isik , Kayode Inadagbo

Traditional artificial neural networks take inspiration from biological networks, using layers of neuron-like nodes to pass information for processing. More realistic models include spiking in the neural network, capturing the electrical…

Machine Learning · Computer Science 2025-03-11 Christopher S. Yang , Sylvester J. Gates , Dulara De Zoysa , Jaehoon Choe , Wolfgang Losert , Corey B. Hart

Spiking Neural Networks (SNNs) are one of the most promising bio-inspired neural networks models and have drawn increasing attention in recent years. The event-driven communication mechanism of SNNs allows for sparse and theoretically…

Neural and Evolutionary Computing · Computer Science 2025-10-29 Andrea Castagnetti , Alain Pegatoquet , Benoît Miramond

In this paper we present a simple microscopic stochastic model describing short term plasticity within a large homogeneous network of interacting neurons. Each neuron is represented by its membrane potential and by the residual calcium…

Probability · Mathematics 2020-01-29 Antonio Galves , Eva Löcherbach , Christophe Pouzat , Errico Presutti

Working memory -- the ability to store and recall precise temporal patterns of neural activity -- remains an open challenge for spiking neural networks (SNNs). We propose a recurrent SNN of $N$ neurons in which each synapse is equipped with…

Neurons and Cognition · Quantitative Biology 2026-04-16 Laurent U Perrinet

Astrocytes, the most abundant type of glial cell, play a fundamental role in memory. Despite most hippocampal synapses being contacted by an astrocyte, there are no current theories that explain how neurons, synapses, and astrocytes might…

Neurons and Cognition · Quantitative Biology 2024-07-24 Leo Kozachkov , Jean-Jacques Slotine , Dmitry Krotov

Spiking neural networks (SNN) are artificial computational models that have been inspired by the brain's ability to naturally encode and process information in the time domain. The added temporal dimension is believed to render them more…

Emerging Technologies · Computer Science 2019-05-29 S. R. Nandakumar , Irem Boybat , Manuel Le Gallo , Evangelos Eleftheriou , Abu Sebastian , Bipin Rajendran

Neurons communicate with downstream systems via sparse and incredibly brief electrical pulses, or spikes. Using these events, they control various targets such as neuromuscular units, neurosecretory systems, and other neurons in connected…

Neurons and Cognition · Quantitative Biology 2026-03-17 Paolo Agliati , André Urbano , Pablo Lanillos , Nasir Ahmad , Marcel van Gerven , Sander Keemink

We present a simple biophysical model for the coupling between synaptic transmission and the local calcium concentration on an enveloping astrocytic domain. This interaction enables the astrocyte to modulate the information flow from…

Neurons and Cognition · Quantitative Biology 2007-05-23 Vladislav Volman , Eshel Ben-Jacob , Herbert Levine

Inspired by the operation of biological brains, Spiking Neural Networks (SNNs) have the unique ability to detect information encoded in spatio-temporal patterns of spiking signals. Examples of data types requiring spatio-temporal processing…

Neural and Evolutionary Computing · Computer Science 2021-04-27 Nicolas Skatchkovsky , Hyeryung Jang , Osvaldo Simeone
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