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We study the fundamental computational problem of approximating optimal transport (OT) equations using neural differential equations (Neural ODEs). More specifically, we develop a novel framework for approximating unbalanced optimal…

Numerical Analysis · Mathematics 2026-05-21 Minh-Nhat Phung , Minh-Binh Tran

Inspired by the matching of supply to demand in logistical problems, the optimal transport (or Monge--Kantorovich) problem involves the matching of probability distributions defined over a geometric domain such as a surface or manifold. In…

Optimization and Control · Mathematics 2018-05-02 Justin Solomon

Data-driven surrogate modeling has emerged as a promising approach for reducing computational expenses of multiscale simulations. Recurrent Neural Network (RNN) is a common choice for modeling of path-dependent behavior. However, previous…

Computational Engineering, Finance, and Science · Computer Science 2023-12-29 Yangzi He , Shabnam J. Semnani

Modeling and simulating how oxygen supply shapes neuronal excitability is crucial for advancing the understanding of brain function in pathological scenarios, such as ischemia. This condition is caused by a reduced blood supply, leading to…

Numerical Analysis · Mathematics 2026-03-19 Francesco Daniele , Caterina B. Leimer Saglio , Stefano Pagani , Paola F. Antonietti

Tracer diffusion in crowded environments is central to many biological and soft matter systems, but quantitative frameworks for linking tracer motion to environmental structure remain limited. Here, we study the transport of rigid tracers…

Soft Condensed Matter · Physics 2026-05-07 Jinseok Lee , Tong Lin , Mengyang Gu , Yimin Luo

Neurons perform computations, and convey the results of those computations through the statistical structure of their output spike trains. Here we present a practical method, grounded in the information-theoretic analysis of prediction, for…

Neurons and Cognition · Quantitative Biology 2022-03-18 Robert Haslinger , Kristina Lisa Klinkner , Cosma Rohilla Shalizi

We consider the freeway network control problem where the aim is to optimize the operation of traffic networks modeled by the Cell Transmission Model via ramp metering and partial mainline demand control. Optimal control problems using the…

Optimization and Control · Mathematics 2018-05-28 Marius Schmitt , John Lygeros

Effective traffic optimization strategies can improve the performance of transportation networks significantly. Most exiting works develop traffic optimization strategies depending on the local traffic states of congested road segments,…

Systems and Control · Electrical Eng. & Systems 2021-12-02 Fengkun Gao , Bo Yang , Cailian Chen , Xinping Guan , Yang Zhang

The need to reason about uncertainty in large, complex, and multi-modal datasets has become increasingly common across modern scientific environments. The ability to transform samples from one distribution $P$ to another distribution $Q$…

Machine Learning · Statistics 2018-11-30 Diego A. Mesa , Justin Tantiongloc , Marcela Mendoza , Todd P. Coleman

Partial-differential-equation (PDE)-constrained optimization is a well-worn technique for acquiring optimal parameters of systems governed by PDEs. However, this approach is limited to providing a single set of optimal parameters per…

Computational Physics · Physics 2024-10-17 Archis S. Joglekar

We analyze the accuracy of traffic simulations metamodels based on neural networks and gradient boosting models (LightGBM), applied to traffic optimization as fitness functions of genetic algorithms. Our metamodels approximate outcomes of…

Machine Learning · Computer Science 2018-12-12 Paweł Gora , Maciej Brzeski , Marcin Możejko , Arkadiusz Klemenko , Adrian Kochański

Traffic congestion in big cities has been proven to be a difficult problem with suboptimal effects in terms of driver delay and frustration, cost, and impact on the environment. In principle, many transportation networks lack a unified…

Physics and Society · Physics 2021-09-08 A. Georgantas , C. Menelaou , C. G. Panayiotou

We consider the problem of incentivization and optimal control of autonomous vehicles for improving traffic congestion. In our scenario, autonomous vehicles must be incentivized in order to participate in traffic improvement. Using the…

Optimization and Control · Mathematics 2020-06-18 Uroš Kalabić , Piyush Grover , Shuchin Aeron

This paper presents a novel partial differential equation (PDE)-based framework for controlling an ensemble of robots, which have limited sensing and actuation capabilities and exhibit stochastic behaviors, to perform mapping and coverage…

Systems and Control · Computer Science 2017-11-30 Karthik Elamvazhuthi , Hendrik Kuiper , Spring Berman

In this paper, we propose a refinement strategy to the well-known Physics-Informed Neural Networks (PINNs) for solving partial differential equations (PDEs) based on the concept of Optimal Transport (OT). Conventional black-box PINNs…

Computational Engineering, Finance, and Science · Computer Science 2021-05-31 Vaishnav Tadiparthi , Raktim Bhattacharya

Molecular signalling in living cells occurs at low copy numbers and is thereby inherently limited by the noise imposed by thermal diffusion. The precision at which biochemical receptors can count signalling molecules is intimately related…

Statistical Mechanics · Physics 2016-09-26 Aljaz Godec , Ralf Metzler

In traditional topology optimization, the computing time required to iteratively update the material distribution within a design domain strongly depends on the complexity or size of the problem, limiting its application in real engineering…

Computational Engineering, Finance, and Science · Computer Science 2024-05-14 Gabriel Garayalde , Matteo Torzoni , Matteo Bruggi , Alberto Corigliano

Complex systems are successfully reduced to interacting elements via the network concept. Transport plays a key role in the survival of networks. For example the specialized signaling cascades of cellular networks filter noise and…

Biological Physics · Physics 2010-10-05 Robin Palotai , Peter Csermely

Why do neurons encode information the way they do? Normative answers to this question model neural activity as the solution to an optimisation problem; for example, the celebrated efficient coding hypothesis frames neural activity as the…

Neurons and Cognition · Quantitative Biology 2026-03-06 William Dorrell , Peter E. Latham , James Whittington

Constitutive models play a crucial role in materials science as they describe the behavior of the materials in mathematical forms. Over the last few decades, the rapid development of manufacturing technologies have led to the discovery of…

Materials Science · Physics 2024-10-17 Xinxin Wu , Yin Zhang , Sheng Mao
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