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Neurons exhibit complex geometry in their branched networks of neurites which is essential to the function of individual neuron but also brings challenges to transport a wide variety of essential materials throughout their neurite networks…

Computational Engineering, Finance, and Science · Computer Science 2021-03-17 Angran Li , Amir Barati Farimani , Yongjie Jessica Zhang

Many living and physical systems such as cell aggregates, tissues or bacterial colonies behave as unconventional systems of particles that are strongly constrained by volume exclusion and shape interactions. Understanding how these…

Quantitative Methods · Quantitative Biology 2026-05-20 Antoine Diez , Jean Feydy

In recent years, augmentation of differentiable PDE solvers with neural networks has shown promising results, particularly in fluid simulations. However, most approaches rely on convolutional neural networks and custom solvers operating on…

Machine Learning · Computer Science 2025-02-27 Matthias Schulz , Gwendal Jouan , Daniel Berger , Stefan Gavranovic , Dirk Hartmann

Many foraging microorganisms rely upon cellular transport networks to deliver nutrients, fluid and organelles between different parts of the organism. Networked organisms ranging from filamentous fungi to slime molds demonstrate a…

Adaptation and Self-Organizing Systems · Physics 2020-12-08 Cassidy Mentus , Marcus Roper

Microtubules (MTs) are dynamic protein filaments essential for intracellular organization and transport, particularly in long-lived cells such as neurons. The plus and minus ends of neuronal MTs switch between growth and shrinking phases,…

Biological Physics · Physics 2025-07-11 Anna C. Nelson , Scott A. McKinley , Melissa M. Rolls , Maria-Veronica Ciocanel

In this work, we introduce a novel first-order nonlocal partial differential equation with saturated diffusion to describe the macroscopic behavior of traffic dynamics. We show how the proposed model is better in comparison with existing…

Optimization and Control · Mathematics 2025-04-02 Dawson Do , Hossein Nick Zinat Matin , Masuma Mollika Miti , Maria Laura Delle Monache

Segmentation of microscopy images constitutes an ill-posed inverse problem due to measurement noise, weak object boundaries, and limited labeled data. Although deep neural networks provide flexible nonparametric estimators, unconstrained…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Seema K. Poudel , Sunny K. Khadka

Many cellular processes rely on the cell's ability to transport material to and from the nucleus. Networks consisting of many microtubules and actin filaments are key to this transport. Recently, the inhibition of intracellular transport…

Subcellular Processes · Quantitative Biology 2020-05-06 Shawn D. Ryan , Zachary McCarthy , Mykhailo Potomkin

Intracellular transport is essential for maintaining proper cellular function in most eukaryotic cells, with perturbations in active transport resulting in several types of disease. Efficient delivery of critical cargos to specific…

Biological Physics · Physics 2016-08-16 David Ando , Nickolay Korabel , Kerwyn Casey Huang , Ajay Gopinathan

Modeling the traffic dynamics is essential for understanding and predicting the traffic spatiotemporal evolution. However, deriving the partial differential equation (PDE) models that capture these dynamics is challenging due to their…

Systems and Control · Electrical Eng. & Systems 2025-05-05 Zihang Wei , Yunlong Zhang , Chenxi Liu , Yang Zhou

Traffic congestion has been a major challenge in many urban road networks. Extensive research studies have been conducted to highlight traffic-related congestion and address the issue using data-driven approaches. Currently, most traffic…

Artificial Intelligence · Computer Science 2023-12-12 Shyam Pratap Singh , Arshad Ali Khan , Riad Souissi , Syed Adnan Yusuf

Optimal transportation of raw material from suppliers to customers is an issue arising in logistics that is addressed here with a continuous model relying on optimal transport theory. A physics informed neuralnetwork method is advocated…

Numerical Analysis · Mathematics 2025-08-19 Alexandre Caboussat , Anna Peruso

Neural networks with a large number of parameters admit a mean-field description, which has recently served as a theoretical explanation for the favorable training properties of "overparameterized" models. In this regime, gradient descent…

Machine Learning · Statistics 2019-03-28 Grant Rotskoff , Samy Jelassi , Joan Bruna , Eric Vanden-Eijnden

This article introduces a representation of dynamic meshes, adapted to some numerical simulations that require controlling the volume of objects with free boundaries, such as incompressible fluid simulation, some astrophysical simulations…

Fluid Dynamics · Physics 2022-01-26 Bruno Lévy

Congestion in transport networks is a topic of theoretical interest and practical importance. In this paper we study the flow of vehicles in urban street networks. In particular, we use a cellular automata model to simulate the motion of…

Physics and Society · Physics 2010-12-16 Salvatore Scellato , Luigi Fortuna , Mattia Frasca , Jesús Gómez-Gardeñes , Vito Latora

Highly-optimized complex transport networks serve crucial functions in many man-made and natural systems such as power grids and plant or animal vasculature. Often, the relevant optimization functional is non-convex and characterized by…

Biological Physics · Physics 2016-09-23 Henrik Ronellenfitsch , Eleni Katifori

Cells are strongly out-of-equilibrium systems driven by continuous energy supply. They carry out many vital functions requiring active transport of various ingredients and organelles, some being small, others being large. The cytoskeleton,…

Biological Physics · Physics 2017-09-20 Cecile Appert-Rolland , Maximilian Ebbinghaus , Ludger Santen

This article revolves around shape and topology optimization, in the applicative context where the objective and constraint functionals depend on the solution to a physical boundary value problem posed on the optimized domain. We introduce…

Optimization and Control · Mathematics 2024-09-13 Charles Dapogny , Bruno Levy , Edouard Oudet

Intracellular transport processes are essential to the healthy development of many organisms as well as more generally to healthy cellular function. The complex dynamics and interactions between protein molecules and filaments on different…

Dynamical Systems · Mathematics 2022-07-27 Maria-Veronica Ciocanel

Traffic state estimation (TSE) fundamentally involves solving high-dimensional spatiotemporal partial differential equations (PDEs) governing traffic flow dynamics from limited, noisy measurements. While Physics-Informed Neural Networks…

Machine Learning · Computer Science 2025-08-19 Zhihao Li , Ting Wang , Guojian Zou , Ruofei Wang , Ye Li
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