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The experimental use of micropatterned quasi-1D substrates has emerged as an useful experimental tool to study the nature of cell-cell interactions and gain insight on collective behaviour of cell colonies. Inspired by these experiments, we…

Soft Condensed Matter · Physics 2025-07-31 Harshal Potdar , Ignacio Pagonabarraga , Sudipto Muhuri

We investigate the emergence of global alignment in colonies of dividing rod-shaped cells under confinement. Using molecular dynamics simulations and continuous modeling, we demonstrate that geometrical anisotropies in the confining…

Soft Condensed Matter · Physics 2021-01-26 Zhihong You , Daniel J. G. Pearce , Luca Giomi

Ecological modelling of increasingly more complex microbial populations is necessary to reflect the highly functional and diverse behaviour inherent to many systems found in reality. Anaerobic digestion is one such process that has…

Dynamical Systems · Mathematics 2015-08-24 Tewfik Sari , Matthew J. Wade

We investigate the hydrodynamic stability and the formation of patterns in a continuum model of epithelial layers, able to account for the interplay between mechanical activity, lateral adhesion and the $6-$fold orientational order…

Soft Condensed Matter · Physics 2025-02-19 Josep-Maria Armengol-Collado , Leonardo Puggioni , Livio N. Carenza , Luca Giomi

We study the interplay of population growth and evolutionary dynamics using a stochastic model based on birth and death events. In contrast to the common assumption of an independent population size, evolution can be strongly affected by…

Populations and Evolution · Quantitative Biology 2012-06-05 Jonas Cremer , Anna Melbinger , Erwin Frey

Motivated by empirical evidence on the interplay between geography, population density and societal interaction, we propose a generative process for the evolution of social structure in cities. Our analytical and simulation results predict…

Physics and Society · Physics 2013-06-12 Wei Pan , Gourab Ghoshal , Coco Krumme , Manuel Cebrian , Alex Pentland

In this paper, we derive second order hydrodynamic traffic models from kinetic-controlled equations for driver-assist vehicles. At the vehicle level we take into account two main control strategies synthesising the action of adaptive cruise…

Statistical Mechanics · Physics 2021-12-30 Giacomo Dimarco , Andrea Tosin , Mattia Zanella

We propose a minimal model of \emph{locally-activated diffusion}, in which the diffusion coefficient of a one-dimensional Brownian particle is modified in a prescribed way --- either increased or decreased --- upon each crossing of the…

Statistical Mechanics · Physics 2015-05-30 O. Bénichou , N. Meunier , S. Redner , R. Voituriez

A biologically motivated individual-based framework for evolution in network-structured populations is developed that can accommodate eco-evolutionary dynamics. This framework is used to construct a network birth and death model. The…

Populations and Evolution · Quantitative Biology 2021-03-19 Karan Pattni , Christopher E. Overton , Kieran J. Sharkey

Comprehensive models of stochastic, clonally reproducing populations are defined in terms of general branching processes, allowing birth during maternal life, as for higher organisms, or by splitting, as in cell division. The populations…

Populations and Evolution · Quantitative Biology 2014-10-14 Kais Hamza , Peter Jagers , Fima C. Klebaner

In this paper we explore the eco-evolutionary dynamics of a predator-prey model, where the prey population is structured according to a certain life history trait. The trait distribution within the prey population is the result of interplay…

Populations and Evolution · Quantitative Biology 2019-03-27 József Z. Farkas , A. Yu. Morozov

The expansion of biological species in natural environments is usually described as the combined effect of individual spatial dispersal and growth. In the case of aquatic ecosystems flow transport can also be extremely relevant as an extra,…

Biological Physics · Physics 2016-08-30 Francesca Tesser , Jos C. H. Zeegers , Herman J. H. Clercx , Luc Brunsveld , Federico Toschi

The bacterium E. coli maneuvers itself to regions with high chemoattractant concentrations by performing two stereotypical moves: `runs', in which it moves in near straight lines, and `tumbles', in which it does not advance but changes…

Cell Behavior · Quantitative Biology 2007-11-29 Yariv Kafri , Rava Azeredo da Silveira

The asymmetric simple exclusion process (ASEP) is a paradigmatic driven-diffusive system that describes the asymmetric diffusion of particles with hardcore interactions in a lattice. Although the ASEP is known as an exactly solvable model,…

Statistical Mechanics · Physics 2024-05-16 Yuki Ishiguro , Jun Sato

The notions of taxis and kinesis are introduced and used to describe two types of behavior of an organism in non-uniform conditions: (i) Taxis means the guided movement to more favorable conditions; (ii) Kinesis is the non-directional…

Populations and Evolution · Quantitative Biology 2018-12-06 A. N. Gorban , N. Çabukoǧlu

Protecting endangered species has been an important issue in ecology. We derive a reaction-diffusion model for a population in a one-dimensional bounded habitat, where the population is subjected to a strong Allee effect in its natural…

Dynamical Systems · Mathematics 2023-08-16 Yu Jin , Rui Peng , Jinfeng Wang

The metabolic network plays a crucial role in regulating bacterial metabolism and growth, but it is subject to inherent molecular stochasticity. Previous studies have utilized flux balance analysis and the maximum entropy method to predict…

Molecular Networks · Quantitative Biology 2024-01-12 Shaohua Guan , Zhichao Zhang , Zihan Zhang , Hualin Shi

Variations of transport efficiency in structured environments between distinct individuals in actively self-propelled systems is both hard to study and poorly understood. Here, we study the transport of a non-tumbling {\ecoli} strain, an…

Soft Condensed Matter · Physics 2023-08-28 Pooja Chopra , David Quint , Ajay Gopinathan , Bin Liu

We introduce and discuss a kinetic framework describing the time evolution of the statistical distributions of a population divided into the compartments of susceptible, infectious, recovered, and resistant in the presence of a microbial…

Populations and Evolution · Quantitative Biology 2026-05-07 Marco Menale , Giuseppe Toscani , Mattia Zanella

Radical shifts in the genetic composition of large cell populations are rare events with quite low probabilities, which direct numerical simulations generally fail to evaluate accurately. In this paper, we develop a theoretical large…

Probability · Mathematics 2024-09-16 Robert Azencott , Brett Geiger , Ilya Timofeyev
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