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Diffusion MRI is a non-invasive, in-vivo biomedical imaging method for mapping tissue microstructure. Applications include structural connectivity imaging of the human brain and detecting microstructural neural changes. However, acquiring…

Image and Video Processing · Electrical Eng. & Systems 2023-10-09 Amir Sadikov , Xinlei Pan , Hannah Choi , Lanya T. Cai , Pratik Mukherjee

Denoising diffusion models offer a promising approach to accelerating magnetic resonance imaging (MRI) and producing diagnostic-level images in an unsupervised manner. However, our study demonstrates that even tiny worst-case potential…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Tianyu Han , Sven Nebelung , Firas Khader , Jakob Nikolas Kather , Daniel Truhn

Diffusion noise is a major source of spectral line broadening in liquid state nano-scale nuclear magnetic resonance with shallow nitrogen-vacancy centres, whose main consequence is a limited spectral resolution. This limitation arises by…

Investigating neural activity from a global brain perspective in-vivo has been in the domain of functional Magnetic Resonance Imaging (fMRI) over the past few decades. The intricate neurovascular couplings that govern fMRI's…

Medical Physics · Physics 2019-03-20 Daniel Nunes , Andrada Ianus , Noam Shemesh

Diffusion models have recently gained popularity for accelerated MRI reconstruction due to their high sample quality. They can effectively serve as rich data priors while incorporating the forward model flexibly at inference time, and they…

Image and Video Processing · Electrical Eng. & Systems 2023-10-20 Batu Ozturkler , Chao Liu , Benjamin Eckart , Morteza Mardani , Jiaming Song , Jan Kautz

Over the past few decades, magnetic resonance imaging has been utilized as a powerful imaging modality to evaluate the structure and function of various organs in the human body,such as the brain. Additionally, diffusion and perfusion MR…

Medical Physics · Physics 2016-12-12 Sanam Assili

Diffusion-weighted magnetic resonance imaging (DW-MRI) can be used to characterise the microstructure of the nervous tissue, e.g. to delineate brain white matter connections in a non-invasive manner via fibre tracking. Magnetic Resonance…

Nonrigid registration is vital to medical image analysis but remains challenging for diffusion MRI (dMRI) due to its high-dimensional, orientation-dependent nature. While classical methods are accurate, they are computationally demanding,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-13 Gianfranco Cortes , Xiaoda Qu , Baba C. Vemuri

Water diffusion gives rise to micron-scale sensitivity of diffusion MRI (dMRI) to cellular-level tissue structure. Precision medicine and quantitative imaging depend on uncovering the information content of dMRI and establishing its…

Medical Physics · Physics 2026-02-03 Santiago Coelho , Jenny Chen , Filip Szczepankiewicz , Els Fieremans , Dmitry S. Novikov

The lack of analytical models describing diffusion time dependence at intermediate time scales in complex tissue microstructure limits the accurate quantification of extracellular diffusivity and tissue microstructure. We introduce TRACED,…

Data-dependent metrics are powerful tools for learning the underlying structure of high-dimensional data. This article develops and analyzes a data-dependent metric known as diffusion state distance (DSD), which compares points using a…

Machine Learning · Statistics 2020-03-10 Lenore Cowen , Kapil Devkota , Xiaozhe Hu , James M. Murphy , Kaiyi Wu

In the recent years, mater-wave interferometry has attracted growing attention due to its unique suitability for high-precision measurements and study of fundamental aspects of quantum theory. Diffraction and interference of matter waves…

Quantum Physics · Physics 2013-05-30 Arseni Goussev

Magnetic Resonance Imaging (MRI) is a critical tool in modern medical diagnostics, yet its prolonged acquisition time remains a critical limitation, especially in time-sensitive clinical scenarios. While undersampling strategies can…

Image and Video Processing · Electrical Eng. & Systems 2025-10-09 Mohammed Alsubaie , Wenxi Liu , Linxia Gu , Ovidiu C. Andronesi , Sirani M. Perera , Xianqi Li

Microscopic diffusion anisotropy ({\mu}A) has been recently gaining increasing attention for its ability to decouple the average compartment anisotropy from orientation dispersion. Advanced diffusion MRI sequences, such as double diffusion…

In this article, we present a Latent Diffusion Model (LDM) for the generation of brain Magnetic Resonance Imaging (MRI), conditioning its generation based on pathology (Healthy, Glioblastoma, Sclerosis, Dementia) and acquisition modality…

Magnetic Resonance Imaging (MRI) is highly susceptible to motion artifacts due to the extended acquisition times required for k-space sampling. These artifacts can compromise diagnostic utility, particularly for dynamic imaging. We propose…

Image and Video Processing · Electrical Eng. & Systems 2025-07-04 Frederic Wang , Jonathan I. Tamir

Diffusion models have recently emerged as powerful learners for simulation-based inference (SBI), enabling fast and accurate estimation of latent parameters from simulated and real data. Their score-based formulation offers a flexible way…

Machine Learning · Statistics 2026-01-30 Jonas Arruda , Niels Bracher , Ullrich Köthe , Jan Hasenauer , Stefan T. Radev

Purpose: Biophysical tissue models are increasingly used in the interpretation of diffusion MRI (dMRI) data, with the potential to provide specific biomarkers of brain microstructural changes. However, the general Standard Model has…

Biological Physics · Physics 2019-03-19 Santiago Coelho , Jose M. Pozo , Sune N. Jespersen , Derek K. Jones , Alejandro F. Frangi

Practically, training diffusion models typically requires explicit time conditioning to guide the network through the denoising sampling process. Especially in deterministic methods like DDIM, the absence of time conditioning leads to…

Machine Learning · Computer Science 2026-04-29 Liuzhuozheng Li , Zhiyuan Zhan , Shuhong Liu , Dengyang Jiang , Zanyi Wang , Guang Dai , Jingdong Wang , Mengmeng Wang
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