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We introduce MedMNIST v2, a large-scale MNIST-like dataset collection of standardized biomedical images, including 12 datasets for 2D and 6 datasets for 3D. All images are pre-processed into a small size of 28x28 (2D) or 28x28x28 (3D) with…

Computer Vision and Pattern Recognition · Computer Science 2023-02-20 Jiancheng Yang , Rui Shi , Donglai Wei , Zequan Liu , Lin Zhao , Bilian Ke , Hanspeter Pfister , Bingbing Ni

Mutual Information (MI) is a powerful statistical measure that quantifies shared information between random variables, particularly valuable in high-dimensional data analysis across fields like genomics, natural language processing, and…

Machine Learning · Computer Science 2024-12-02 Andre O. Falcao

From the simple measurement of tissue attributes in pathology workflow to designing an explainable diagnostic/prognostic AI tool, access to accurate semantic segmentation of tissue regions in histology images is a prerequisite. However,…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Mostafa Jahanifar , Neda Zamani Tajeddin , Navid Alemi Koohbanani , Nasir Rajpoot

Histological images are critical in the diagnosis and treatment of cancers. Unfortunately, the current method for capturing these microscopy images require resource intensive tissue preparation that delays diagnosis for many days to a few…

In this paper, we introduce a new dataset in the medical field of Traumatic Brain Injury (TBI), called TBI-IT, which includes both electronic medical records (EMRs) and head CT images. This dataset is designed to enhance the accuracy of…

Image and Video Processing · Electrical Eng. & Systems 2024-03-15 Jie Li , Jiaying Wen , Tongxin Yang , Fenglin Cai , Miao Wei , Zhiwei Zhang , Li Jiang

Histopathological images contain abundant phenotypic information and pathological patterns, which are the gold standards for disease diagnosis and essential for the prediction of patient prognosis and treatment outcome. In recent years,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-26 Linhao Qu , Siyu Liu , Xiaoyu Liu , Manning Wang , Zhijian Song

Many medical imaging techniques utilize fitting approaches for quantitative parameter estimation and analysis. Common examples are pharmacokinetic modeling in DCE MRI/CT, ADC calculations and IVIM modeling in diffusion-weighted MRI and…

This paper presents an innovative set of tools to support a methodology for the multichannel interpolation (MCI) of a discrete signal. It is shown that a bandlimited signal $f$ can be exactly reconstructed from finite samples of $g_k$…

Information Theory · Computer Science 2019-04-12 Dong Cheng , Kit Ian Kou

The task of synthesizing novel views from a single image has useful applications in virtual reality and mobile computing, and a number of approaches to the problem have been proposed in recent years. A Multiplane Image (MPI) estimates the…

Computer Vision and Pattern Recognition · Computer Science 2023-09-26 Numair Khan , Douglas Lanman , Lei Xiao

Background: Alignment of biological sequences such as DNA, RNA or proteins is one of the most widely used tools in computational bioscience. All existing alignment algorithms rely on heuristic scoring schemes based on biological expertise.…

Genomics · Quantitative Biology 2008-10-27 Orion Penner , Peter Grassberger , Maya Paczuski

Humans make accurate decisions by interpreting complex data from multiple sources. Medical diagnostics, in particular, often hinge on human interpretation of multi-modal information. In order for artificial intelligence to make progress in…

Computer Vision and Pattern Recognition · Computer Science 2018-11-20 Faisal Mahmood , Ziyun Yang , Thomas Ashley , Nicholas J. Durr

In neuroimaging, MRI tissue properties characterize underlying neurobiology, provide quantitative biomarkers for neurological disease detection and analysis, and can be used to synthesize arbitrary MRI contrasts. Estimating tissue…

Image and Video Processing · Electrical Eng. & Systems 2021-07-07 Divya Varadarajan , Katherine L. Bouman , Andre van der Kouwe , Bruce Fischl , Adrian V. Dalca

Human medical data can be challenging to obtain due to data privacy concerns, difficulties conducting certain types of experiments, or prohibitive associated costs. In many settings, data from animal models or in-vitro cell lines are…

Transmission matrices, mapping the propagation of light from one end of the tissue to the other, form an important mathematical tool in the analysis of tissue scattering and the design of wavefront shaping systems. To understand the…

Optics · Physics 2025-04-01 Anat Levin , Marina Alterman

The scarcity of labeled data often impedes the application of deep learning to the segmentation of medical images. Semi-supervised learning seeks to overcome this limitation by exploiting unlabeled examples in the learning process. In this…

Computer Vision and Pattern Recognition · Computer Science 2021-06-25 Jizong Peng , Marco Pedersoli , Christian Desrosiers

Multiplex Imaging (MI) enables the simultaneous visualization of multiple biological markers in separate imaging channels at subcellular resolution, providing valuable insights into cell-type heterogeneity and spatial organization. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-11-07 Simon Gutwein , Daria Lazic , Thomas Walter , Sabine Taschner-Mandl , Roxane Licandro

CLARITY is a method for converting biological tissues into translucent and porous hydrogel-tissue hybrids. This facilitates interrogation with light sheet microscopy and penetration of molecular probes while avoiding physical slicing. In…

Computer Vision and Pattern Recognition · Computer Science 2017-08-14 Kwame S. Kutten , Nicolas Charon , Michael I. Miller , J. T. Ratnanather , Jordan Matelsky , Alexander D. Baden , Kunal Lillaney , Karl Deisseroth , Li Ye , Joshua T. Vogelstein

Portable medical imaging (PMI) has emerged as an important solution for point-of-care diagnosis in emergency, rural, and resource-limited settings where conventional imaging infrastructure is not readily available. Modalities such as…

Image and Video Processing · Electrical Eng. & Systems 2026-04-20 Yassine Habchi , Hamza Kheddar , Muhammad Ali Qureshi , Mohamed Seghier , Azeddine Beghdadi

Image harmonization is an important preprocessing strategy to address domain shifts arising from data acquired using different machines and scanning protocols in medical imaging. However, benchmarking the effectiveness of harmonization…

Image and Video Processing · Electrical Eng. & Systems 2024-08-28 Abhijeet Parida , Zhifan Jiang , Roger J. Packer , Robert A. Avery , Syed M. Anwar , Marius G. Linguraru