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Diffusion models are powerful generative models that simulate the reverse of diffusion processes using score functions to synthesize data from noise. The sampling process of diffusion models can be interpreted as solving the reverse…

Machine Learning · Computer Science 2022-09-30 Beomsu Kim , Jong Chul Ye

This work studies distributed (probability) density estimation of large-scale systems. Such problems are motivated by many density-based distributed control tasks in which the real-time density of the swarm is used as feedback information,…

Systems and Control · Electrical Eng. & Systems 2021-06-03 Tongjia Zheng , Hai Lin

Atomistic simulations are widely used to investigate reactive processes but are often limited by the rare event problem due to kinetic bottlenecks. We recently introduced an enhanced sampling approach based on the committor function,…

Computational Physics · Physics 2026-03-02 Enrico Trizio , Giorgia Rossi , Michele Parrinello

Designing an appropriate set of collective variables is crucial to the success of several enhanced sampling methods. Here we focus on how to obtain such variables from information limited to the metastable states. We characterize these…

Chemical Physics · Physics 2020-04-08 Luigi Bonati , Valerio Rizzi , Michele Parrinello

As multipath components (MPCs) are experimentally observed to appear in clusters, cluster-based channel models have been focused in the wireless channel study. However, most of the MPC clustering algorithms for MIMO channels with delay and…

Information Theory · Computer Science 2022-06-29 Yi Chen , Chong Han , Jia He , Guangjian Wang

A data driven, kernel-based method for approximating the leading Koopman eigenvalues, eigenfunctions, and modes in problems with high dimensional state spaces is presented. This approach approximates the Koopman operator using a set of…

Dynamical Systems · Mathematics 2015-07-29 Matthew O. Williams , Clarence W. Rowley , Ioannis G. Kevrekidis

A central problem in data analysis is the low dimensional representation of high dimensional data, and the concise description of its underlying geometry and density. In the analysis of large scale simulations of complex dynamical systems,…

Numerical Analysis · Mathematics 2007-05-23 Boaz Nadler , Stephane Lafon , Ronald R. Coifman , Ioannis G. Kevrekidis

We introduce the state-of-the-art deep learning Denoising Diffusion Probabilistic Model (DDPM) as a method to infer the volume or number density of giant molecular clouds (GMCs) from projected mass surface density maps. We adopt…

Astrophysics of Galaxies · Physics 2023-06-28 Duo Xu , Jonathan C. Tan , Chia-Jung Hsu , Ye Zhu

Recent research in tabular data synthesis has focused on single tables, whereas real-world applications often involve complex data with tens or hundreds of interconnected tables. Previous approaches to synthesizing multi-relational…

Artificial Intelligence · Computer Science 2024-11-15 Wei Pang , Masoumeh Shafieinejad , Lucy Liu , Stephanie Hazlewood , Xi He

Diffusion models have recently emerged as powerful tools for missing data imputation by modeling the joint distribution of observed and unobserved variables. However, existing methods, typically based on stochastic denoising diffusion…

Artificial Intelligence · Computer Science 2025-08-06 Youran Zhou , Mohamed Reda Bouadjenek , Sunil Aryal

We propose score dynamics (SD), a general framework for learning accelerated evolution operators with large timesteps from molecular-dynamics simulations. SD is centered around scores, or derivatives of the transition log-probability with…

Computational Physics · Physics 2024-03-08 Tim Hsu , Babak Sadigh , Vasily Bulatov , Fei Zhou

A distributed adaptive algorithm is proposed to solve a node-specific parameter estimation problem where nodes are interested in estimating parameters of local interest, parameters of common interest to a subset of nodes and parameters of…

Computers and Society · Computer Science 2023-07-19 Jorge Plata-Chaves , Nikola Bogdanovic , Kostas Berberidis

Denoising diffusion probabilistic models (DDPMs) (Ho et al. 2020) have shown impressive results on image and waveform generation in continuous state spaces. Here, we introduce Discrete Denoising Diffusion Probabilistic Models (D3PMs),…

Machine Learning · Computer Science 2023-02-23 Jacob Austin , Daniel D. Johnson , Jonathan Ho , Daniel Tarlow , Rianne van den Berg

Protein function does not solely depend on structure but often relies on dynamical transitions between distinct conformations. Despite this fact, our ability to characterize or predict protein dynamics is substantially less developed…

Statistical Mechanics · Physics 2026-05-08 Michael A. Sauer , Souvik Mondal , Brandon Neff , Sthitadhi Maiti , Matthias Heyden

The dynamics of physical systems that require high-dimensional representation can often be captured in a few meaningful degrees of freedom called collective variables (CVs). However, identifying CVs is challenging and constitutes a…

Chemical Physics · Physics 2024-04-03 Jakub Rydzewski

Debiased collaborative filtering aims to learn an unbiased prediction model by removing different biases in observational datasets. To solve this problem, one of the simple and effective methods is based on the propensity score, which…

Information Retrieval · Computer Science 2024-05-01 Haoxuan Li , Chunyuan Zheng , Yanghao Xiao , Peng Wu , Zhi Geng , Xu Chen , Peng Cui

We present an unsupervised data processing workflow that is specifically designed to obtain a fast conformational clustering of long molecular dynamics simulation trajectories. In this approach we combine two dimensionality reduction…

Chemical Physics · Physics 2023-08-09 Simon Hunkler , Kay Diederichs , Oleksandra Kukharenko , Christine Peter

The description of the dynamics of a complex, high-dimensional system in terms of a low-dimensional set of collective variables Y can be fruitful if the low dimensional representation satisfies a Langevin equation with drift and diffusion…

Biomolecules · Quantitative Biology 2016-11-29 R. Meloni , C. Camilloni , G. Tiana

We study parametric inference for ergodic diffusion processes with a degenerate diffusion matrix. Existing research focuses on a particular class of hypo-elliptic SDEs, with components split into `rough'/`smooth' and noise from rough…

Statistics Theory · Mathematics 2024-05-29 Yuga Iguchi , Alexandros Beskos , Matthew Graham

This paper studies the original discrete-time denoising diffusion probabilistic model (DDPM) from a probabilistic point of view. We present three main theoretical results. First, we show that the time-dependent score function associated…

Probability · Mathematics 2026-01-13 Yumiharu Nakano