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Cone-beam CT (CBCT)-based online adaptive radiotherapy calls for accurate auto-segmentation to reduce the time cost for physicians to edit contours. However, deep learning (DL)-based direct segmentation of CBCT images is a challenging task,…

Medical Physics · Physics 2023-02-22 Xiao Liang , Howard Morgan , Ti Bai , Michael Dohopolski , Dan Nguyen , Steve Jiang

Over half a million individuals are diagnosed with head and neck cancer each year worldwide. Radiotherapy is an important curative treatment for this disease, but it requires manual time consuming delineation of radio-sensitive organs at…

The accurate segmentation of organs-at-risk (OARs) in head and neck CT images is a critical step for radiation therapy of head and neck cancer patients. However, manual delineation for numerous OARs is time-consuming and laborious, even for…

Image and Video Processing · Electrical Eng. & Systems 2021-10-26 Shuai Wang , Theodore Yanagihara , Bhishamjit Chera , Colette Shen , Pew-Thian Yap , Jun Lian

Purpose: Segmentation of organs-at-risk (OARs) is a bottleneck in current radiation oncology pipelines and is often time consuming and labor intensive. In this paper, we propose an atlas-based semi-supervised registration algorithm to…

Computer Vision and Pattern Recognition · Computer Science 2019-11-26 Charles Huang , Masoud Badiei , Hyunseok Seo , Ming Ma , Xiaokun Liang , Dante Capaldi , Michael Gensheimer , Lei Xing

The purpose of this study is to develop a deep learning based method that can automatically generate segmentations on cone-beam CT (CBCT) for head and neck online adaptive radiation therapy (ART), where expert-drawn contours in planning CT…

Medical Physics · Physics 2021-02-02 Xiao Liang , Howard Morgan , Dan Nguyen , Steve Jiang

Automatic segmentation of organs-at-risk (OAR) in computed tomography (CT) is an essential part of planning effective treatment strategies to combat lung and esophageal cancer. Accurate segmentation of organs surrounding tumours helps…

Computer Vision and Pattern Recognition · Computer Science 2019-05-21 Sulaiman Vesal , Nishant Ravikumar , Andreas Maier

Automatic segmentation of organs-at-risk (OARs) in CT scans using convolutional neural networks (CNNs) is being introduced into the radiotherapy workflow. However, these segmentations still require manual editing and approval by clinicians…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Edward G. A. Henderson , Andrew F. Green , Marcel van Herk , Eliana M. Vasquez Osorio

Medical imaging has been employed to support medical diagnosis and treatment. It may also provide crucial information to surgeons to facilitate optimal surgical preplanning and perioperative management. Essentially, semi-automatic organ and…

Image and Video Processing · Electrical Eng. & Systems 2021-01-26 K. E. Sengun , Y. T. Cetin , M. S Guzel , S. Can , E. Bostanci

Automatic localization and segmentation of organs-at-risk (OAR) in CT are essential pre-processing steps in medical image analysis tasks, such as radiation therapy planning. For instance, the segmentation of OAR surrounding tumors enables…

Computer Vision and Pattern Recognition · Computer Science 2022-03-02 Fernando Navarro , Guido Sasahara , Suprosanna Shit , Ivan Ezhov , Jan C. Peeken , Stephanie E. Combs , Bjoern H. Menze

Image registration, the process of aligning two or more images, is the core technique of many (semi-)automatic medical image analysis tasks. Recent studies have shown that deep learning methods, notably convolutional neural networks…

Computer Vision and Pattern Recognition · Computer Science 2021-09-09 Bob D. de Vos , Floris F. Berendsen , Max A. Viergever , Hessam Sokooti , Marius Staring , Ivana Isgum

Accurate segmentation of organ at risk (OAR) play a critical role in the treatment planning of image guided radiation treatment of head and neck cancer. This segmentation task is challenging for both human and automatic algorithms because…

Computer Vision and Pattern Recognition · Computer Science 2019-10-14 Yueyue Wang , Liang Zhao , Zhijian Song , Manning Wang

Most of the deep learning based medical image registration algorithms focus on brain image registration tasks.Compared with brain registration, the chest CT registration has larger deformation, more complex background and region over-lap.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Cheng Wang , Qiyu Gao , Fandong Zhang , Shu Zhang , Yizhou Yu

In adaptive radiotherapy, deformable image registration is often conducted between the planning CT and treatment CT (or cone beam CT) to generate a deformation vector field (DVF) for dose accumulation and contour propagation. The auto…

Medical Physics · Physics 2015-06-12 Xuejun Gu , Bin Dong , Jing Wang , John Yordy , Loren Mell , Xun Jia , Steve B. Jiang

Deformable medical image registration is a fundamental task in medical image analysis with applications in disease diagnosis, treatment planning, and image-guided interventions. Despite significant advances in deep learning based…

Machine Learning · Computer Science 2026-02-10 Muhammad Zafar Iqbal , Ghazanfar Farooq Siddiqui , Anwar Ul Haq , Imran Razzak

When delineating lesions from medical images, a human expert can always keep in mind the anatomical structure behind the voxels. However, although high-quality (though not perfect) anatomical information can be retrieved from computed…

Image and Video Processing · Electrical Eng. & Systems 2023-12-04 Rongzhao Zhang , Zhian Bai , Ruoying Yu , Wenrao Pang , Lingyun Wang , Lifeng Zhu , Xiaofan Zhang , Huan Zhang , Weiguo Hu

Deep convolutional neural networks (CNNs) are state-of-the-art for semantic image segmentation, but typically require many labeled training samples. Obtaining 3D segmentations of medical images for supervised training is difficult and labor…

Computer Vision and Pattern Recognition · Computer Science 2019-07-29 Zhenlin Xu , Marc Niethammer

Planning of radiotherapy involves accurate segmentation of a large number of organs at risk, i.e. organs for which irradiation doses should be minimized to avoid important side effects of the therapy. We propose a deep learning method for…

Image and Video Processing · Electrical Eng. & Systems 2019-07-04 Pawel Mlynarski , Hervé Delingette , Hamza Alghamdi , Pierre-Yves Bondiau , Nicholas Ayache

Medical imaging spans diverse tasks and modalities which play a pivotal role in disease diagnosis, treatment planning, and monitoring. This study presents a novel exploration, being the first to systematically evaluate segmentation,…

Image and Video Processing · Electrical Eng. & Systems 2025-02-27 Anyimadu Daniel Tweneboah , Suleiman Taofik Ahmed , Hossain Mohammad Imran

Organs-at-risk (OAR) delineation in computed tomography (CT) is an important step in Radiation Therapy (RT) planning. Recently, deep learning based methods for OAR delineation have been proposed and applied in clinical practice for separate…

Image and Video Processing · Electrical Eng. & Systems 2020-01-14 Shanlin Sun , Yang Liu , Narisu Bai , Hao Tang , Xuming Chen , Qian Huang , Yong Liu , Xiaohui Xie

Online adaptive radiotherapy (ART) requires accurate and efficient auto-segmentation of target volumes and organs-at-risk (OARs) in mostly cone-beam computed tomography (CBCT) images. Propagating expert-drawn contours from the pre-treatment…

Computer Vision and Pattern Recognition · Computer Science 2023-05-10 Xiao Liang , Jaehee Chun , Howard Morgan , Ti Bai , Dan Nguyen , Justin C. Park , Steve Jiang
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