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Nonlinear, i.e., multi-photon microscopy is a powerful technique for imaging deep into biological tissues. Its penetration depth can be increased further using adaptive optics. In this work, we present a fast, feedback-based adaptive-optics…

We report a singly resonant continuous-wave optical parametric oscillator (SRO), which is pumped by a semiconductor laser system and operates in the mid-infrared region (2.9 to 3.6 {\mu}m). Fast tuning of the mid-infrared output wavelength…

Optics · Physics 2018-07-06 Ville Ulvila , Markku Vainio

The expansion of telecommunications incurs increasingly severe crosstalk and interference, and a physical layer cognitive method, called blind source separation (BSS), can effectively address these issues. BSS requires minimal prior…

Signal Processing · Electrical Eng. & Systems 2023-03-22 Weipeng Zhang , Alexander Tait , Chaoran Huang , Thomas Ferreira de Lima , Simon Bilodeau , Eric Blow , Aashu Jha , Bhavin J. Shastri , Paul Prucnal

Optical spectroscopy plays an essential role across scientific research and industry for non-contact materials analysis1-3, increasingly through in-situ or portable platforms4-6. However, when considering low-light-level applications,…

We propose a novel technique of microscopy to overcome the effects of both scattering and limitation of the accessible depth due to the objective working distance. By combining Laser Optical Feedback Imaging (LOFI) with Acoustic Photon…

Coherent Anti Stokes Raman Scattering (CARS) offers many advantages for nonlinear bio-imaging, thanks to its sub-cellular spatial resolution and unique chemical specificity. Its working principle requires two incident pulsed laser beams…

This paper investigates the reconfigurable intelligent surface (RIS) assisted spatial scattering modulation (SSM) scheme for millimeter-wave (mmWave) multiple-input multiple-output (MIMO) systems, in which line-of-sight (LoS) and…

Information Theory · Computer Science 2023-07-28 Xusheng Zhu , Wen Chen , Zhendong Li , Qingqing Wu , Ziheng Zhang , Kunlun Wang , Jun Li

Surface plasmon resonance (SPR) has been widely utilized to improve the absorption performance in the photosensors. Graphene has emerged as a promising plasmonic material, which supports tunable SPR and shows significant flexibility over…

Optics · Physics 2018-09-11 Shuyuan Xiao , Tao Wang , Xiaoyun Jiang , Boyun Wang , Chen Xu

Minimally invasive imaging with fiber optic endoscopes is crucial for in vivo visualization of tissue morphology, particularly because visualizing structural changes in tissue can support applications such as the early diagnosis of tumors.…

Optical microscopy has long been the standard method for diagnosis in cytopathology. Whole slide scanners can image and digitize large sample areas automatically, but are slow, expensive and therefore not widely available. Clinical…

Molecular optomechanics stems from the description of Raman scattering in the presence of an optical resonator using a cavity optomechanics formalism. We extend the molecular optomechanics formalism to the case of hybrid…

Hydrogen detection is of great importance in chemical and energy industries. Optical fiber hydrogen sensors show flexibility and compactness and have the potential for distributed analysis. However, traditional fiber sensors encounter a…

Optics · Physics 2019-05-16 F. Yang , Y. Zhao , Y. Qi , Y. Z. Tan , H. L. Ho , W. Jin

A reconfigurable intelligent surface (RIS) is a nearly-passive flat layer made of inexpensive elements that can add a tunable phase shift to the impinging electromagnetic wave and are controlled by a low-power electronic circuit. This paper…

Signal Processing · Electrical Eng. & Systems 2022-05-04 Stefano Buzzi , Emanuele Grossi , Marco Lops , Luca Venturino

Histological examination is crucial for cancer diagnosis, including hematoxylin and eosin (H&E) staining for mapping morphology and immunohistochemistry (IHC) staining for revealing chemical information. Recently developed two-color…

Tissues and Organs · Quantitative Biology 2023-09-22 Hongli Ni , Chinmayee Prabhu Dessai , Haonan Lin , Wei Wang , Shaoxiong Chen , Yuhao Yuan , Xiaowei Ge , Jianpeng Ao , Nolan Vild , Ji-Xin Cheng

Fiber-based endoscopes utilizing multi-core fiber (MCF) bundles offer the capability to image deep within the human body, making them well-suited for imaging applications in minimally invasive surgery or diagnosis. However, the optical…

Raman spectroscopy enables broadband, multi-species gas analysis by providing access to an entire vibrational spectrum in a single measurement. However, the sensitivity of gas-phase Raman sensing is often limited by weak signals and…

Raman spectroscopy (RS) has been widely used for disease diagnosis, e.g., cardiovascular disease (CVD), owing to its efficiency and component-specific testing capabilities. A series of popular deep learning methods have recently been…

Image and Video Processing · Electrical Eng. & Systems 2023-04-20 Bo Yu , Hechang Chen , Chengyou Jia , Hongren Zhou , Lele Cong , Xiankai Li , Jianhui Zhuang , Xianling Cong

Photoacoustic imaging has emerged in the past decades. Compared with the traditional medical imaging mode, it has better imaging performance and has great development potential in the field of biological imaging. In traditional…

Medical Physics · Physics 2020-09-03 Xianlin Song , Jianshuang Wei , Jianmin Xiong , Lingfang Song

Developing compact, broadband mid-infrared coherent sources for applications in spectroscopy and sensing remains a pressing challenge in photonics. However, material limitations and integration constraints have restricted the accessible…

Silicon photonics enables on-chip ultra-high bandwidth optical communications networks which is critical for the future of microelectronics1,2. By encoding information on-chip using multiple wavelength channels through the process of…