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Related papers: CEST MR fingerprinting (CEST-MRF) for Brain Tumor …

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Purpose: To develop an automated machine-learning-based method for the discovery of rapid and quantitative chemical exchange saturation transfer (CEST) MR fingerprinting acquisition and reconstruction protocols. Methods: An MR physics…

Medical Physics · Physics 2022-02-01 Or Perlman , Bo Zhu , Moritz Zaiss , Matthew S. Rosen , Christian T. Farrar

Purpose: To develop a model-based deep neural network for high-quality image reconstruction of undersampled multi-coil chemical exchange saturation transfer (CEST) data. Theory and Methods: Inspired by the variational network, the CEST…

Medical Physics · Physics 2023-05-26 Jianping Xu , Tao Zu , Yi-Cheng Hsu , Xiaoli Wang , Kannie W. Y. Chan , Yi Zhang

Purpose: To substantially shorten the acquisition time required for quantitative 3D chemical exchange saturation transfer (CEST) and semisolid magnetization transfer (MT) imaging and allow for rapid chemical exchange parameter map…

Purpose: To understand the influence of various acquisition parameters on the ability of CEST MR-Fingerprinting (MRF) to discriminate different chemical exchange parameters and to provide tools for optimal acquisition schedule design and…

Medical Physics · Physics 2019-11-04 Or Perlman , Kai Herz , Moritz Zaiss , Ouri Cohen , Matthew S. Rosen , Christian T. Farrar

In MR fingerprinting (MRF) reconstruction, measured data is pattern-matched to simulated signals to extract quantitative tissue parameters. A critical drawback to this approach is the exponentially increasing compute time for mapping of…

Medical Physics · Physics 2024-07-17 Victoria Y. Yu , Kathryn R. Tringale , Ricardo Otazo , Ouri Cohen

Purpose: To develop a motion-robust and geometrically-accurate quantitative CEST approach using radial k-space sampling, locally low-rank reconstruction and neural network quantification. Methods: The acquisition schedule was generated via…

Medical Physics · Physics 2026-03-27 Ouri Cohen , Elizabeth J. Sutton , Robert J. Young , Ricardo Otazo

Purpose: To develop a fast magnetic resonance fingerprinting (MRF) method for quantitative chemical exchange saturation transfer (CEST) imaging. Methods: We implemented a CEST-MRF method to quantify the chemical exchange rate and volume…

Medical Physics · Physics 2024-07-17 Ouri Cohen , Shuning Huang , Michael T. McMahon , Matthew S. Rosen , Christian T. Farrar

Brain tumors analysis is important in timely diagnosis and effective treatment to cure patients. Tumor analysis is challenging because of tumor morphology like size, location, texture, and heteromorphic appearance in the medical images. In…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Mirza Mumtaz Zahoor , Shahzad Ahmad Qureshi , Saddam Hussain Khan , Asifullah Khan

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) plays an important role in diagnosis and grading of brain tumor. Although manual DCE biomarker extraction algorithms boost the diagnostic yield of DCE-MRI by providing…

Introduction: Quantification of dynamic contrast-enhanced (DCE)-MRI has the potential to provide valuable clinical information, but robust pharmacokinetic modeling remains a challenge for clinical adoption. Methods: A 7-layer neural network…

Medical Physics · Physics 2024-05-22 Ouri Cohen , Soudabeh Kargar , Sungmin Woo , Alberto Vargas , Ricardo Otazo

Objectives: Most cancer data sources lack information on metastatic recurrence. Electronic medical records (EMRs) and population-based cancer registries contain complementary information on cancer treatment and outcomes, yet are rarely used…

Quantitative Methods · Quantitative Biology 2021-07-22 Albee Y. Ling , Allison W. Kurian , Jennifer L. Caswell-Jin , George W. Sledge , Nigam H. Shah , Suzanne R. Tamang

Purpose: To evaluate the quality of deep learning reconstruction for prospectively accelerated intraoperative magnetic resonance imaging (iMRI) during resective brain tumor surgery. Materials and Methods: Accelerated iMRI was performed…

To simultaneously fit multiple-pool effects, spectrally selective 3D CEST imaging typically requires single-shot readouts to save time. However, to date, FLASH and EPI have been the primary pulse sequences used for this purpose. They suffer…

Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic and radiotherapy (RT) planning tool, offering detailed insights into the anatomy of the human body. The extensive scan time is stressful for patients, who must remain motionless…

Image and Video Processing · Electrical Eng. & Systems 2023-11-23 Shahinur Alam , Jinsoo Uh , Alexander Dresner , Chia-ho Hua , Khaled Khairy

Detecting and segmenting brain metastases is a tedious and time-consuming task for many radiologists, particularly with the growing use of multi-sequence 3D imaging. This study demonstrates automated detection and segmentation of brain…

Image and Video Processing · Electrical Eng. & Systems 2019-12-30 Endre Grøvik , Darvin Yi , Michael Iv , Elisabeth Tong , Daniel L. Rubin , Greg Zaharchuk

One of the most important tasks in medical image processing is the brain's whole tumor segmentation. It assists in quicker clinical assessment and early detection of brain tumors, which is crucial for lifesaving treatment procedures of…

Computer Vision and Pattern Recognition · Computer Science 2020-09-15 Apurva Pandya , Catherine Samuel , Nisargkumar Patel , Vaibhavkumar Patel , Thangarajah Akilan

This retrospective-prospective study evaluated whether a deep learning-based MRI reconstruction algorithm can preserve diagnostic quality in brain MRI scans accelerated up to fourfold, using both public and prospective clinical data. The…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 Jonathan I. Mandel , Shivaprakash Hiremath , Hedyeh Keshtgar , Timothy Scholl , Sadegh Raeisi

Brain tumors are abnormal cell growths in the central nervous system (CNS), and their timely detection is critical for improving patient outcomes. This paper proposes an automatic and efficient deep-learning framework for brain tumor…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Ahta-Shamul Hoque Emran , Hafija Akter , Abdullah Al Shiam , Abu Saleh Musa Miah , Anichur Rahman , Fahmid Al Farid , Hezerul Abdul Karim

Purpose: To develop and validate a framework for rapid, accurate, and reproducible whole-brain, multi-pool chemical exchange saturation transfer (CEST) imaging at 3T, addressing challenges of long acquisition times and confounding factors.…

Medical Physics · Physics 2025-09-16 Yupeng Wu , Siyuan Fang , Siyuan Wang , Caixia Fu , Jianqi Li

PURPOSE: Demonstrate a novel fast method for reconstruction of multi-dimensional MR Fingerprinting (MRF) data using Deep Learning methods. METHODS: A neural network (NN) is defined using the TensorFlow framework and trained on simulated MRF…

Computer Vision and Pattern Recognition · Computer Science 2024-07-17 Ouri Cohen , Bo Zhu , Matthew S. Rosen
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