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Machine learning (ML) classifiers always benefit from more informative input features. We seek to auto-generate stronger feature sets in order to address the difficulty that ML methods often experience given limited training data. A wide…

Emerging Technologies · Computer Science 2020-09-15 Charles B Delahunt , J Nathan Kutz

Insects, such as fruit flies and honey bees, can solve simple associative learning tasks and learn abstract concepts such as "sameness" and "difference", which is viewed as a higher-order cognitive function and typically thought to depend…

Computer Vision and Pattern Recognition · Computer Science 2021-09-15 Jinyung Hong , Theodore P. Pavlic

Continual learning in computational systems is challenging due to catastrophic forgetting. We discovered a two layer neural circuit in the fruit fly olfactory system that addresses this challenge by uniquely combining sparse coding and…

Machine Learning · Computer Science 2021-12-23 Yang Shen , Sanjoy Dasgupta , Saket Navlakha

The olfactory system employs responses of an ensemble of odorant receptors (ORs) to sense molecules and to generate olfactory percepts. Here we hypothesized that ORs can be viewed as 3D spatial filters that extract molecular features…

Machine Learning · Computer Science 2024-12-13 Sergey Shuvaev , Khue Tran , Khristina Samoilova , Cyrille Mascart , Alexei Koulakov

Local computation in microcircuits is an essential feature of distributed information processing in vertebrate and invertebrate brains. The insect antennal lobe represents a spatially confined local network that processes high-dimensional…

Neurons and Cognition · Quantitative Biology 2012-12-27 Anneke Meyer , Giovanni Galizia , Martin P. Nawrot

In the principal cells of the insect mushroom body, the Kenyon cells (KC), olfactory information is represented by a spatially and temporally sparse code. Each odor stimulus will activate only a small portion of neurons and each stimulus…

Biological Physics · Physics 2010-07-21 Farzad Farkhooi , Eilif Muller , Martin P. Nawrot

We seek to (i) characterize the learning architectures exploited in biological neural networks for training on very few samples, and (ii) port these algorithmic structures to a machine learning context. The Moth Olfactory Network is among…

Machine Learning · Computer Science 2019-01-29 Charles B. Delahunt , J. Nathan Kutz

The Drosophila mushroom body (MB) is known to be involved in olfactory learning and memory; the synaptic plasticity of the Kenyon cell (KC) to mushroom body output neuron (MBON) synapses plays a key role in the learning process. Previous…

Neurons and Cognition · Quantitative Biology 2025-09-25 Katherine Xie , Gabriel Koch Ocker

The mushroom body is the key network for the representation of learned olfactory stimuli in Drosophila and insects. The sparse activity of Kenyon cells, the principal neurons in the mushroom body, plays a key role in the learned…

Machine Learning · Computer Science 2019-07-22 Luca Manneschi , Andrew C. Lin , Eleni Vasilaki

Biologically inspired neural networks offer alternative avenues to model data distributions. FlyVec is a recent example that draws inspiration from the fruit fly's olfactory circuit to tackle the task of learning word embeddings.…

The mushroom body of the fruit fly brain is one of the best studied systems in neuroscience. At its core it consists of a population of Kenyon cells, which receive inputs from multiple sensory modalities. These cells are inhibited by the…

Computation and Language · Computer Science 2021-03-16 Yuchen Liang , Chaitanya K. Ryali , Benjamin Hoover , Leopold Grinberg , Saket Navlakha , Mohammed J. Zaki , Dmitry Krotov

The insect olfactory system, which includes the antennal lobe (AL), mushroom body (MB), and ancillary structures, is a relatively simple neural system capable of learning. Its structural features, which are widespread in biological neural…

Neurons and Cognition · Quantitative Biology 2018-02-09 Charles B. Delahunt , Jeffrey A. Riffell , J. Nathan Kutz

Recordings from neurons in the insects' olfactory primary processing center, the antennal lobe (AL), reveal that the AL is able to process the input from chemical receptors into distinct neural activity patterns, called olfactory neural…

Neurons and Cognition · Quantitative Biology 2014-08-27 Eli Shlizerman , Jeffrey A. Riffell , J. Nathan Kutz

Molecular odor prediction is the process of using a molecule's structure to predict its smell. While accurate prediction remains challenging, AI models can suggest potential odors. Existing methods, however, often rely on basic descriptors…

Machine Learning · Computer Science 2025-05-02 Hong Xin Xie , Jian De Sun , Fan Fu Xue , Zi Fei Han , Shan Shan Feng , Qi Chen

Neural network techniques are widely applied to obtain high-quality distributed representations of words, i.e., word embeddings, to address text mining, information retrieval, and natural language processing tasks. Recently, efficient…

Computation and Language · Computer Science 2014-09-08 Qing Cui , Bin Gao , Jiang Bian , Siyu Qiu , Tie-Yan Liu

Predicting the relationship between a molecule's structure and its odor remains a difficult, decades-old task. This problem, termed quantitative structure-odor relationship (QSOR) modeling, is an important challenge in chemistry, impacting…

State-of-the-art visual place recognition performance is currently being achieved utilizing deep learning based approaches. Despite the recent efforts in designing lightweight convolutional neural network based models, these can still be…

Computer Vision and Pattern Recognition · Computer Science 2021-09-24 Bruno Arcanjo , Bruno Ferrarini , Michael Milford , Klaus D. McDonald-Maier , Shoaib Ehsan

Studies of insect olfactory processing indicate that odors are represented by rich spatio-temporal patterns of neural activity. These patterns are very difficult to predict a priori, yet they are stimulus specific and reliable upon repeated…

Neurons and Cognition · Quantitative Biology 2007-05-23 M. I. Rabinovich , R. Huerta , A. Volkovskii , Henry D. I. Abarbanel , G. Laurent

Odor detection underpins food safety, environmental monitoring, medical diagnostics, and many more fields. The current artificial sensors developed for odor detection struggle with complex mixtures while non-invasive recordings lack…

Machine Learning · Computer Science 2025-08-14 Matin Hassanloo , Ali Zareh , Mehmet Kemal Özdemir

Odor source localization is a fundamental challenge in molecular communication, environmental monitoring, disaster response, industrial safety, and robotics. In this study, we investigate three major approaches: Bayesian filtering, machine…

Signal Processing · Electrical Eng. & Systems 2025-02-12 Ayse Sila Okcu , Ozgur B. Akan
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