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The performance of machine learning models in drug discovery is highly dependent on the quality and consistency of the underlying training data. Due to limitations in dataset sizes, many models are trained by aggregating bioactivity data…

Machine Learning · Computer Science 2025-11-21 Vincent Fan , Regina Barzilay

The EM algorithm is a method for finding the maximum likelihood estimate of a model in the presence of missing data. Unfortunately, EM does not produce a parameter covariance matrix for standard errors. Supplemented EM (SEM; Meng & Rubin,…

Computation · Statistics 2016-05-04 Joshua N. Pritikin

Language models (LMs) exhibit and amplify many types of undesirable biases learned from the training data, including gender bias. However, we lack tools for effectively and efficiently changing this behavior without hurting general language…

Computation and Language · Computer Science 2023-10-20 Abhijith Chintam , Rahel Beloch , Willem Zuidema , Michael Hanna , Oskar van der Wal

We propose the use of Agent Based Models (ABMs) inside a reinforcement learning framework in order to better understand the relationship between automated decision making tools, fairness-inspired statistical constraints, and the social…

Computers and Society · Computer Science 2019-03-25 Efrén Cruz Cortés , Debashis Ghosh

The integration of Large Language Models (LLMs) into software engineering has driven a transition from traditional rule-based systems to autonomous agentic systems capable of solving complex problems. However, systematic progress is…

Software Engineering · Computer Science 2025-10-24 Jiale Guo , Suizhi Huang , Mei Li , Dong Huang , Xingsheng Chen , Regina Zhang , Zhijiang Guo , Han Yu , Siu-Ming Yiu , Pietro Lio , Kwok-Yan Lam

Reading comprehension is a key for individual success, yet the assessment of question difficulty remains challenging due to the extensive human annotation and large-scale testing required by traditional methods such as linguistic analysis…

Computation and Language · Computer Science 2025-02-26 Yoshee Jain , John Hollander , Amber He , Sunny Tang , Liang Zhang , John Sabatini

Integrating multiple observational studies for meta-analysis has sparked much interest. The presented R package WMAP (Weighted Meta-Analysis with Pseudo-Population) addresses a critical gap in the implementation of integrative weighting…

Methodology · Statistics 2025-07-01 Subharup Guha , Mengqi Xu , Kashish Priyam , Yi Li

We introduce Matched Machine Learning, a framework that combines the flexibility of machine learning black boxes with the interpretability of matching, a longstanding tool in observational causal inference. Interpretability is paramount in…

Methodology · Statistics 2023-04-05 Marco Morucci , Cynthia Rudin , Alexander Volfovsky

Traditionally, spline or kernel approaches in combination with parametric estimation are used to infer the linear coefficient (fixed effects) in a partially linear mixed-effects model for repeated measurements. Using machine learning…

Methodology · Statistics 2023-04-03 Corinne Emmenegger , Peter Bühlmann

Artificial Intelligence (AI) or Machine Learning (ML) systems have been widely adopted as value propositions by companies in all industries in order to create or extend the services and products they offer. However, developing AI/ML systems…

Software Engineering · Computer Science 2020-11-10 Elizamary Nascimento , Anh Nguyen-Duc , Ingrid Sundbø , Tayana Conte

In the field of materials science and engineering, statistical analysis and machine learning techniques have recently been used to predict multiple material properties from an experimental design. These material properties correspond to…

Methodology · Statistics 2022-07-15 Keisuke Teramoto , Kei Hirose

With the emerging trend of GPT models, we have established a framework called AutoML-GPT that integrates a comprehensive set of tools and libraries. This framework grants users access to a wide range of data preprocessing techniques,…

Machine Learning · Computer Science 2023-09-06 Yun-Da Tsai , Yu-Che Tsai , Bo-Wei Huang , Chun-Pai Yang , Shou-De Lin

Model evaluation is a critical component in supervised machine learning classification analyses. Traditional metrics do not currently incorporate case difficulty. This renders the classification results unbenchmarked for generalization.…

Machine Learning · Computer Science 2023-02-10 Adrienne Kline , Joon Lee

Transformer-based language models (LMs) continue to achieve state-of-the-art performance on natural language processing (NLP) benchmarks, including tasks designed to mimic human-inspired "commonsense" competencies. To better understand the…

Computation and Language · Computer Science 2022-05-13 Antonio Laverghetta , Animesh Nighojkar , Jamshidbek Mirzakhalov , John Licato

One source of software project challenges and failures is the systematic errors introduced by human cognitive biases. Although extensively explored in cognitive psychology, investigations concerning cognitive biases have only recently…

Software Engineering · Computer Science 2022-03-22 Rahul Mohanani , Iflaah Salman , Burak Turhan , Pilar Rodriguez , Paul Ralph

This study introduces another application of software engineering tools, conceptual modeling, which can be applied to other fields of research. One way to strengthen the relationship between software engineering and other fields is to…

Artificial Intelligence · Computer Science 2020-12-22 Sabah Al-Fedaghi

Item response theory (IRT) models have been widely used in educational measurement testing. When there are repeated observations available for individuals through time, a dynamic structure for the latent trait of ability needs to be…

Applications · Statistics 2013-04-17 Xiaojing Wang , James O. Berger , Donald S. Burdick

During a psychotherapy session, the counselor typically adopts techniques which are codified along specific dimensions (e.g., 'displays warmth and confidence', or 'attempts to set up collaboration') to facilitate the evaluation of the…

Computation and Language · Computer Science 2021-10-26 Nikolaos Flemotomos , Victor R. Martinez , Zhuohao Chen , Torrey A. Creed , David C. Atkins , Shrikanth Narayanan

This paper studies the inference of the regression coefficient matrix under multivariate response linear regressions in the presence of hidden variables. A novel procedure for constructing confidence intervals of entries of the coefficient…

Methodology · Statistics 2022-01-21 Xin Bing , Wei Cheng , Huijie Feng , Yang Ning

Knowledge Tracing (KT) aims to predict learners' future performance from past interactions. While recent KT approaches have improved via learning item representations aligned with Knowledge Components, they overlook the procedural dynamics…

Computation and Language · Computer Science 2026-04-10 Jun Seo , Sangwon Ryu , Heejin Do , Hyounghun Kim , Gary Geunbae Lee