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We present a method for estimating parameters in stochastic models of biochemical reaction networks by fitting steady-state distributions using Wasserstein distances. We simulate a reaction network at different parameter settings and train…

Quantitative Methods · Quantitative Biology 2020-01-29 Kaan Öcal , Ramon Grima , Guido Sanguinetti

Fitting a simplifying model with several parameters to real data of complex objects is a highly nontrivial task, but enables the possibility to get insights into the objects physics. Here, we present a method to infer the parameters of the…

Data Analysis, Statistics and Probability · Physics 2018-12-21 Johannes Oberpriller , T. A. Enßlin

The performance of many machine learning models depends on their hyper-parameter settings. Bayesian Optimization has become a successful tool for hyper-parameter optimization of machine learning algorithms, which aims to identify optimal…

Machine Learning · Computer Science 2020-08-04 Lidan Wang , Franck Dernoncourt , Trung Bui

Bayesian statistical inference for Generalized Linear Models (GLMs) with parameters lying on a constrained space is of general interest (e.g., in monotonic or convex regression), but often constructing valid prior distributions supported on…

Methodology · Statistics 2021-09-02 Rahul Ghosal , Sujit K. Ghosh

Regularized system identification is the major advance in system identification in the last decade. Although many promising results have been achieved, it is far from complete and there are still many key problems to be solved. One of them…

Systems and Control · Electrical Eng. & Systems 2023-04-05 Yue Ju , Biqiang Mu , Lennart Ljung , Tianshi Chen

We propose a novel class of temporal high-order parametric finite element methods for solving a wide range of geometric flows of curves and surfaces. By incorporating the backward differentiation formulae (BDF) for time discretization into…

Numerical Analysis · Mathematics 2024-08-21 Wei Jiang , Chunmei Su , Ganghui Zhang

Accurate identification of parameters of load models is essential in power system computations, including simulation, prediction, and stability and reliability analysis. Conventional point estimation based composite load modeling approaches…

Systems and Control · Computer Science 2019-03-27 Chang Fu , Zhe Yu , Di Shi , Haifeng Li , Caisheng Wang , Zhiwei Wang , Jie Li

A common approach to modelling extreme values is to consider the excesses above a high threshold as realisations of a non-homogeneous Poisson process. While this method offers the advantage of modelling using threshold-invariant extreme…

Applications · Statistics 2016-12-09 Paul Sharkey , Jonathan A. Tawn

A common task is the determination of system parameters from spectroscopy, where one compares the experimental spectrum with calculated spectra, that depend on the desired parameters. Here we discuss an approach based on a machine learning…

Quantum Physics · Physics 2022-05-04 Farhad Taher-Ghahramani , Fulu Zheng , Alexander Eisfeld

Vizing's theorem guarantees that every graph with maximum degree $\Delta$ admits an edge coloring using $\Delta + 1$ colors. In online settings - where edges arrive one at a time and must be colored immediately - a simple greedy algorithm…

Data Structures and Algorithms · Computer Science 2025-07-30 Joakim Blikstad , Ola Svensson , Radu Vintan , David Wajc

Bayesian optimization (BO) is a widely-used method for optimizing expensive (to evaluate) problems. At the core of most BO methods is the modeling of the objective function using a Gaussian Process (GP) whose covariance is selected from a…

Gaussian process regression has proven very powerful in statistics, machine learning and inverse problems. A crucial aspect of the success of this methodology, in a wide range of applications to complex and real-world problems, is…

Statistics Theory · Mathematics 2021-03-18 Yifan Chen , Houman Owhadi , Andrew M. Stuart

Bayesian Optimization is a sample-efficient black-box optimization procedure that is typically applied to problems with a small number of independent objectives. However, in practice we often wish to optimize objectives defined over many…

Machine Learning · Computer Science 2021-10-29 Wesley J. Maddox , Maximilian Balandat , Andrew Gordon Wilson , Eytan Bakshy

Gaussian graphical models are widely used to infer dependence structures. Bayesian methods are appealing to quantify uncertainty associated with structural learning, i.e., the plausibility of conditional independence statements given the…

Methodology · Statistics 2025-11-05 Deborah Sulem , Jack Jewson , David Rossell

We study the parameterized complexity of a broad class of problems called "local graph partitioning problems" that includes the classical fixed cardinality problems as max k-vertex cover, k-densest subgraph, etc. By developing a technique…

Computational Complexity · Computer Science 2013-06-11 Edouard Bonnet , Bruno Escoffier , Vangelis Th. Paschos , Emeric Tourniaire

Here we consider the problem of denoising features associated to complex data, modeled as signals on a graph, via a smoothness prior. This is motivated in part by settings such as single-cell RNA where the data is very high-dimensional, but…

Machine Learning · Computer Science 2023-12-12 Sam Leone , Xingzhi Sun , Michael Perlmutter , Smita Krishnaswamy

In this paper, we consider the so-called Shape Invariant Model which stands for the estimation of a function f0 submitted to a random translation of law g0 in a white noise model. We are interested in such a model when the law of the…

Statistics Theory · Mathematics 2013-03-13 Dominique Bontemps , Sebastien Gadat

Fairness concerns are increasingly critical as machine learning models are deployed in high-stakes applications. While existing fairness-aware methods typically intervene at the model level, they often suffer from high computational costs,…

Machine Learning · Computer Science 2025-11-11 Yixuan Zhang , Jiabin Luo , Zhenggang Wang , Feng Zhou , Quyu Kong

This paper developed an inference problem for Vasicek model driven by a general Gaussian process. We construct a least squares estimator and a moment estimator for the drift parameters of the Vasicek model, and we prove the consistency and…

Statistics Theory · Mathematics 2020-09-25 Xingzhi Pei

Due to the increasing complexity of technical systems, accurate first principle models can often not be obtained. Supervised machine learning can mitigate this issue by inferring models from measurement data. Gaussian process regression is…

Systems and Control · Electrical Eng. & Systems 2023-07-11 Armin Lederer , Jonas Umlauft , Sandra Hirche
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