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The efficiency of nanopore-based biosequencing techniques requires fast anionic polymer capture by like-charged pores followed by a prolonged translocation process. We show that this condition can be achieved by setting a pressure-solvation…

Soft Condensed Matter · Physics 2018-06-20 Sahin Buyukdagli

Porous graphene has high mechanical strength and atomic layer thickness, which make it a promising material for material separation and biomolecule sensing. Electrostatic interactions between charges in aqueous solution are a kind of strong…

Chemical Physics · Physics 2016-08-02 Yinghua Qiu , Kun Li , Weiyu Chen , Wei Si , Qiyan Tan , Yunfei Chen

Ion channels regulate many essential properties of biological cells, especially the membrane potential. Despite decades of efforts on artificial channels, it remains a great challenge to mimic the dipole potential-an indispensable…

Short nanopores have various applications in biosensing, desalination, and energy conversion. Here, the modulation of charged exterior surfaces on ionic transport is investigated through simulations with sub-200 nm long nanopores under…

Soft Condensed Matter · Physics 2024-02-08 Long Ma , Zhe Liu , Jia Man , Jianyong Li , Zuzanna S. Siwy , Yinghua Qiu

We probe the electrostatic mechanism driving adsorption of polyelectrolytes onto like-charged membranes upon the addition of tri- and tetravalent counterions to a bathing monovalent salt solution. We develop a one-loop-dressed strong…

Soft Condensed Matter · Physics 2019-10-02 Sahin Buyukdagli , Rudolf Podgornik

The comprehensive depiction of the many-body effects governing nanoconfined electrolytes is an essential step for the conception of nanofluidic devices with optimized performance. By incorporating self-consistently multivalent charges into…

Soft Condensed Matter · Physics 2020-12-14 Sahin Buyukdagli

Aqueous cations permeate subnanoscale pores by crossing free energy barriers dominated by competing enthalpic contributions from transiently decreased ion-solvent and increased ion-pore electrostatic interactions. This commonly accepted…

Mesoscale and Nanoscale Physics · Physics 2025-09-18 Yechan Noh , Demian Riccardi , Alex Smolyanitsky

Controlled breakdown has recently emerged as a highly appealing technique to fabricate solid-state nanopores for a wide range of biosensing applications. This technique relies on applying an electric field of approximately 0.6-1 V/nm across…

We investigate the dielectrophoretic motion of charge-neutral, polarizable nanocolloids through molecular dynamics simulations. Comparison to analytical results derived for continuum systems shows that the discrete charge distributions on…

Soft Condensed Matter · Physics 2009-11-13 Emppu Salonen , Emma Terama , Ilpo Vattulainen , Mikko Karttunen

Nanopores spanning synthetic membranes have been used as key components in proof-of-principle nanofluidic applications, particularly those involving manipulation of biomolecules or sequencing of DNA. The only practical way of manipulating…

Mesoscale and Nanoscale Physics · Physics 2016-09-21 Tom Chou

The development of high-performance multifunctional polymer-based electronic circuits is a major step towards future flexible electronics. Here, we demonstrate a tunable approach to fabricate such devices based on rationally designed…

The ability to induce regions of high and low ionic concentration adjacent to a permeselective membrane or nanochannel subject to an externally applied electric field (a phenomenon termed concentration-polarization) has been used for a…

Fluid Dynamics · Physics 2018-03-12 Sinwook Park , Gilad Yossifon

The movement of small particles and molecules through membranes is widespread and has far-reaching implications. Consequently, the development of mathematical models is essential for understanding these processes on a micro level, leading…

We propose a mechanism for the stabilization/destabilization of cell membranes by multivalent ions with an emphasis on its implications for the division and fusion of cells. We find that multivalent cations preferentially adsorbed onto a…

Soft Condensed Matter · Physics 2007-05-23 Bae-Yeun Ha

Nanopores in solid state membranes are a tool able to probe nanofluidic phenomena or can act as a single molecular sensor. They also have diverse applications in filtration, desalination or osmotic power generation. Many of these…

Soft Condensed Matter · Physics 2020-12-02 Sebastian J. Davis , Michal Macha , Andrey Chernev , David M. Huang , Aleksandra Radenovic , Sanjin Marion

It is well established that when multivalent counterions or salts are added to a solution of highly-charged polyelectrolytes (PEs), correlation effects can cause charge inversion of the PE, leading to electrophoretic mobility (EM) reversal.…

Soft Condensed Matter · Physics 2023-06-14 Hossein Vahid , Alberto Scacchi , Maria Sammalkorpi , Tapio Ala-Nissila

Microfluidic channels with embedded ion permselective medium under the application of electric current are commonly used for electrokinetic processes as on-chip ion concentration polarization (ICP) and bioparticle preconcentration to…

Fluid Dynamics · Physics 2022-11-22 Barak Sabbagh , Sinwook Park , Gilad Yossifon

The ability of semipermeable membranes to selectively impede the transport of undesirable solutes is key to many applications. Yet, obtaining a systematic understanding of how membrane structure affects selectivity remains elusive due to…

Soft Condensed Matter · Physics 2020-01-03 Hessam Malmir , Razi Epsztein , Menachem Elimelech , Amir Haji-Akbari

We model and simulate a nanopore sensor that selectively binds analyte ions. This binding leads to the modulation of the local concentrations of the ions of the background electrolyte (KCl), and, thus, to the modulation of the ionic current…

Applied Physics · Physics 2019-11-07 Eszter Mádai , Mónika Valiskó , Dezső Boda

This paper studies mechanism of preconcentration of charged particles in a straight micro-channel embedded with permselective membranes, by numerically solving coupled transport equations of ions, charged particles and solvent fluid without…

Fluid Dynamics · Physics 2018-02-14 Zirui Li , Wei Liu , Yudan Zhu , Xiaohua Lu , Yuantong Gu , Jongyoon Han