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Deep learning (DL) models, despite their remarkable success, remain vulnerable to small input perturbations that can cause erroneous outputs, motivating the recent proposal of probabilistic robustness (PR) as a complementary alternative to…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Zheng Wang , Yi Zhang , Siddartha Khastgir , Carsten Maple , Xingyu Zhao

Blind image deblurring is an important yet very challenging problem in low-level vision. Traditional optimization based methods generally formulate this task as a maximum-a-posteriori estimation or variational inference problem, whose…

Image and Video Processing · Electrical Eng. & Systems 2021-06-08 Hui Wang , Zongsheng Yue , Qian Zhao , Deyu Meng

We propose a deformable registration algorithm based on unsupervised learning of a low-dimensional probabilistic parameterization of deformations. We model registration in a probabilistic and generative fashion, by applying a conditional…

Computer Vision and Pattern Recognition · Computer Science 2018-07-23 Julian Krebs , Tommaso Mansi , Boris Mailhé , Nicholas Ayache , Hervé Delingette

Alzheimer's disease (AD), the predominant form of dementia, is a growing global challenge, emphasizing the urgent need for accurate and early diagnosis. Current clinical diagnoses rely on radiologist expert interpretation, which is prone to…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Simisola Odimayo , Chollette C. Olisah , Khadija Mohammed

Neural networks (NNs) can achieved high performance in various fields such as computer vision, and natural language processing. However, deploying NNs in resource-constrained safety-critical systems has challenges due to uncertainty in the…

Machine Learning · Computer Science 2024-01-17 Soyed Tuhin Ahmed

Retrospective analysis of brain MRI scans acquired in the clinic has the potential to enable neuroimaging studies with sample sizes much larger than those found in research datasets. However, analysing such clinical images "in the wild" is…

Image and Video Processing · Electrical Eng. & Systems 2023-01-06 Benjamin Billot , Magdamo Colin , Sean E. Arnold , Sudeshna Das , Juan. E. Iglesias

Affine image registration is a cornerstone of medical image analysis. While classical algorithms can achieve excellent accuracy, they solve a time-consuming optimization for every image pair. Deep-learning (DL) methods learn a function that…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Malte Hoffmann , Andrew Hoopes , Douglas N. Greve , Bruce Fischl , Adrian V. Dalca

Radiation exposure in positron emission tomography (PET) imaging limits its usage in the studies of radiation-sensitive populations, e.g., pregnant women, children, and adults that require longitudinal imaging. Reducing the PET radiotracer…

Image and Video Processing · Electrical Eng. & Systems 2021-07-22 Viswanath P. Sudarshan , Uddeshya Upadhyay , Gary F. Egan , Zhaolin Chen , Suyash P. Awate

Background. Fully automatic analysis of myocardial perfusion MRI datasets enables rapid and objective reporting of stress/rest studies in patients with suspected ischemic heart disease. Developing deep learning techniques that can analyze…

Subject motion in whole-body dynamic PET introduces inter-frame mismatch and seriously impacts parametric imaging. Traditional non-rigid registration methods are generally computationally intense and time-consuming. Deep learning approaches…

Image and Video Processing · Electrical Eng. & Systems 2022-06-29 Xueqi Guo , Bo Zhou , David Pigg , Bruce Spottiswoode , Michael E. Casey , Chi Liu , Nicha C. Dvornek

Voxel-based Morphometry (VBM) has emerged as a powerful approach in neuroimaging research, utilized in over 7,000 studies since the year 2000. Using Magnetic Resonance Imaging (MRI) data, VBM assesses variations in the local density of…

In this paper, we propose a deep learning approach for image registration by predicting deformation from image appearance. Since obtaining ground-truth deformation fields for training can be challenging, we design a fully convolutional…

Computer Vision and Pattern Recognition · Computer Science 2018-02-14 Jingfan Fan , Xiaohuan Cao , Pew-Thian Yap , Dinggang Shen

Current state-of-the-art deep learning segmentation methods have not yet made a broad entrance into the clinical setting in spite of high demand for such automatic methods. One important reason is the lack of reliability caused by models…

Computer Vision and Pattern Recognition · Computer Science 2019-06-18 Jörg Sander , Bob D. de Vos , Jelmer M. Wolterink , Ivana Išgum

Deep learning based deformable registration methods have become popular in recent years. However, their ability to generalize beyond training data distribution can be poor, significantly hindering their usability. LUMIR brain registration…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Joel Honkamaa , Pekka Marttinen

Deep learning has revolutionized image registration by its ability to handle diverse tasks while achieving significant speed advantages over conventional approaches. Current approaches, however, often employ globally uniform smoothness…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Xiang Chen , Fengting Zhang , Qinghao Liu , Min Liu , Kun Wu , Yaonan Wang , Hang Zhang

Voxel-based multiple testing is widely used in neuroimaging data analysis. Traditional false discovery rate (FDR) control methods often ignore the spatial dependence among the voxel-based tests and thus suffer from substantial loss of…

Machine Learning · Statistics 2024-05-06 Taehyo Kim , Hai Shu , Qiran Jia , Mony J. de Leon

Deep learning has advanced deformable image registration, surpassing traditional optimization-based methods in both accuracy and efficiency. However, learning-based models are widely believed to be sensitive to domain shift, with robustness…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Mingzhen Shao , Sarang Joshi

Deep diffeomorphic registration faces significant challenges for high-dimensional images, especially in terms of memory limits. Existing approaches either downsample original images, or approximate underlying transformations, or reduce…

Image and Video Processing · Electrical Eng. & Systems 2021-05-25 Ankita Joshi , Yi Hong

Accurate segmentation of MR brain tissue is a crucial step for diagnosis, surgical planning, and treatment of brain abnormalities. Automatic and reliable segmenta-tion methods are required to assist doctor. Over the last few years, deep…

Computer Vision and Pattern Recognition · Computer Science 2018-07-25 Yang Deng , Yao Sun , Yongpei Zhu , Shuo Zhang , Mingwang Zhu , Kehong Yuan

We propose DeepMapping, a novel registration framework using deep neural networks (DNNs) as auxiliary functions to align multiple point clouds from scratch to a globally consistent frame. We use DNNs to model the highly non-convex mapping…

Computer Vision and Pattern Recognition · Computer Science 2019-04-10 Li Ding , Chen Feng