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One of the notable fields in studying the genetics of cancer is disease gene identification which affects disease treatment and drug discovery. Many researches have been done in this field. Genome-wide association studies (GWAS) are one of…

Computational Engineering, Finance, and Science · Computer Science 2016-04-27 Zahra Razaghi-Moghadama , Razieh Abdollahia , Sama Goliaeib , Morteza Ebrahimia

Classifying logo images is a challenging task as they contain elements such as text or shapes that can represent anything from known objects to abstract shapes. While the current state of the art for logo classification addresses the…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Marisa Bernabeu , Antonio Javier Gallego , Antonio Pertusa

Background and purpose: Heart disease has been one of the most important causes of death in the last 10 years, so the use of classification methods to diagnose and predict heart disease is very important. If this disease is predicted before…

Machine Learning · Computer Science 2021-03-16 Jafar Abdollahi , Babak Nouri-Moghaddam

Healthcare is one of the most important aspects of human life. Heart disease is known to be one of the deadliest diseases which is hampering the lives of many people around the world. Heart disease must be detected early so the loss of…

Machine Learning · Computer Science 2024-09-04 Shadab Hussain , Santosh Kumar Nanda , Susmith Barigidad , Shadab Akhtar , Md Suaib , Niranjan K. Ray

The computer-aided disease diagnosis from radiomic data is important in many medical applications. However, developing such a technique relies on annotating radiological images, which is a time-consuming, labor-intensive, and expensive…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Zhiyuan Li , Hailong Li , Anca L. Ralescu , Jonathan R. Dillman , Nehal A. Parikh , Lili He

Deep learning based medical image diagnosis has shown great potential in clinical medicine. However, it often suffers two major difficulties in practice: 1) only limited labeled samples are available due to expensive annotation costs over…

Machine Learning · Computer Science 2019-11-19 Yifan Zhang , Ying Wei , Peilin Zhao , Shuaicheng Niu , Qingyao Wu , Mingkui Tan , Junzhou Huang

We address the issue of binary classification from positive and unlabeled data (PU classification) with a selection bias in the positive data. During the observation process, (i) a sample is exposed to a user, (ii) the user then returns the…

Machine Learning · Computer Science 2023-03-09 Masahiro Kato , Shuting Wu , Kodai Kureishi , Shota Yasui

We consider the problem of detecting and estimating the strength of association between a trait of interest and alleles or haplotypes in a small genomic region (e.g. a gene or a gene complex), when no direct information on that region is…

Applications · Statistics 2008-04-11 Rodrigo Labouriau , Poul Sørensen , Helle R. Juul-Madsen

Positive--Unlabeled (PU) learning considers settings in which only positive and unlabeled data are available, while negatives are missing or left unlabeled. This situation is common in real applications where annotating reliable negatives…

Machine Learning · Computer Science 2025-10-30 Miao Zhang , Junpeng Li , Changchun Hua , Yana Yang

We propose a simple approach which combines the strengths of probabilistic graphical models and deep learning architectures for solving the multi-label classification task, focusing specifically on image and video data. First, we show that…

Machine Learning · Computer Science 2023-02-07 Shivvrat Arya , Yu Xiang , Vibhav Gogate

Identifying genes associated with complex human diseases is one of the main challenges of human genetics and computational medicine. To answer this question, millions of genetic variants get screened to identify a few of importance. To…

Genomics · Quantitative Biology 2015-09-01 Aziz M. Mezlini , Fabio Fuligni , Adam Shlien , Anna Goldenberg

Unsupervised domain adaptation (UDA) methods have been broadly utilized to improve the models' adaptation ability in general computer vision. However, different from the natural images, there exist huge semantic gaps for the nuclei from…

Computer Vision and Pattern Recognition · Computer Science 2022-07-05 Canran Li , Dongnan Liu , Haoran Li , Zheng Zhang , Guangming Lu , Xiaojun Chang , Weidong Cai

Machine learning (ML) algorithms are optimized for the distribution represented by the training data. For outlier data, they often deliver predictions with equal confidence, even though these should not be trusted. In order to deploy…

Image and Video Processing · Electrical Eng. & Systems 2021-03-17 Milda Pocevičiūtė , Gabriel Eilertsen , Claes Lundström

Neoplasms (NPs) and neurological diseases and disorders (NDDs) are amongst the major classes of diseases underlying deaths of a disproportionate number of people worldwide. To determine if there exist some distinctive features in the local…

Molecular Networks · Quantitative Biology 2022-12-27 Vikram Singh , Vikram Singh

Diagnosis prediction is a critical task in healthcare, where timely and accurate identification of medical conditions can significantly impact patient outcomes. Traditional machine learning and deep learning models have achieved notable…

Machine Learning · Computer Science 2025-01-09 Qiuhao Lu , Rui Li , Elham Sagheb , Andrew Wen , Jinlian Wang , Liwei Wang , Jungwei W. Fan , Hongfang Liu

When searching for gene pathways leading to specific disease outcomes, additional information on gene characteristics is often available that may facilitate to differentiate genes related to the disease from irrelevant background when…

Machine Learning · Statistics 2018-09-10 Yunpeng Zhao , Qing Pan , Chengan Du

Computer vision-based methods have valuable use cases in precision medicine, and recognizing facial phenotypes of genetic disorders is one of them. Many genetic disorders are known to affect faces' visual appearance and geometry. Automated…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Ömer Sümer , Fabio Hellmann , Alexander Hustinx , Tzung-Chien Hsieh , Elisabeth André , Peter Krawitz

In this paper, a robust weighted score for unbalanced data (ROWSU) is proposed for selecting the most discriminative feature for high dimensional gene expression binary classification with class-imbalance problem. The method addresses one…

Machine Learning · Statistics 2024-01-24 Zardad Khan , Amjad Ali , Saeed Aldahmani

Active learning aims to select samples to be annotated that yield the largest performance improvement for the learning algorithm. Many methods approach this problem by measuring the informativeness of samples and do this based on the…

Machine Learning · Computer Science 2021-08-02 Javad Zolfaghari Bengar , Bogdan Raducanu , Joost van de Weijer

Despite remarkable success in unpaired image-to-image translation, existing systems still require a large amount of labeled images. This is a bottleneck for their real-world applications; in practice, a model trained on labeled CelebA…

Computer Vision and Pattern Recognition · Computer Science 2019-12-09 Hyojin Bahng , Sunghyo Chung , Seungjoo Yoo , Jaegul Choo