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Collaborative filtering (CF) stands as a cornerstone in recommender systems, yet effectively leveraging the massive unlabeled data presents a significant challenge. Current research focuses on addressing the challenge of unlabeled data by…

Information Retrieval · Computer Science 2024-12-25 Yuhan Zhao , Rui Chen , Qilong Han , Hongtao Song , Li Chen

State-of-the-art, high capacity deep neural networks not only require large amounts of labelled training data, they are also highly susceptible to label errors in this data, typically resulting in large efforts and costs and therefore…

Machine Learning · Computer Science 2020-07-20 Christian Haase-Schütz , Rainer Stal , Heinz Hertlein , Bernhard Sick

Plant diseases serve as one of main threats to food security and crop production. It is thus valuable to exploit recent advances of artificial intelligence to assist plant disease diagnosis. One popular approach is to transform this problem…

Computer Vision and Pattern Recognition · Computer Science 2020-03-19 Ruifeng Shi , Deming Zhai , Xianming Liu , Junjun Jiang , Wen Gao

Positive-Unlabeled (PU) learning aims to learn a model with rare positive samples and abundant unlabeled samples. Compared with classical binary classification, the task of PU learning is much more challenging due to the existence of many…

Computer Vision and Pattern Recognition · Computer Science 2022-12-01 Chengming Xu , Chen Liu , Siqian Yang , Yabiao Wang , Shijie Zhang , Lijie Jia , Yanwei Fu

Gene panel selection aims to identify the most informative genomic biomarkers in label-free genomic datasets. Traditional approaches, which rely on domain expertise, embedded machine learning models, or heuristic-based iterative…

Genomics · Quantitative Biology 2025-09-12 Meng Xiao , Weiliang Zhang , Xiaohan Huang , Hengshu Zhu , Min Wu , Xiaoli Li , Yuanchun Zhou

Rare diseases affect a relatively small number of people, which limits investment in research for treatments and cures. Developing an efficient method for rare disease detection is a crucial first step towards subsequent clinical research.…

Machine Learning · Computer Science 2018-12-04 Wenyuan Li , Yunlong Wang , Yong Cai , Corey Arnold , Emily Zhao , Yilian Yuan

We propose a simple and efficient method for ranking features in multi-label classification. The method produces a ranking of features showing their relevance in predicting labels, which in turn allows to choose a final subset of features.…

Machine Learning · Computer Science 2016-02-25 Paweł Teisseyre

The prediction of disease risk factors can screen vulnerable groups for effective prevention and treatment, so as to reduce their morbidity and mortality. Machine learning has a great demand for high-quality labeling information, and…

Machine Learning · Computer Science 2024-06-26 Yang Lin , Muqing Li , Ziyi Zhu , Yinqiu Feng , Lingxi Xiao , Zexi Chen

The task of node classification is to infer unknown node labels, given the labels for some of the nodes along with the network structure and other node attributes. Typically, approaches for this task assume homophily, whereby neighboring…

Social and Information Networks · Computer Science 2021-09-15 Arpit Merchant , Michael Mathioudakis

AI-assisted nuclei segmentation in histopathological images is a crucial task in the diagnosis and treatment of cancer diseases. It decreases the time required to manually screen microscopic tissue images and can resolve the conflict…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Hesham Ali , Idriss Tondji , Mennatullah Siam

In this work we present a deep learning approach to conduct hypothesis-free, transcriptomics-based matching of drugs for diseases. Our proposed neural network architecture is trained on approved drug-disease indications, taking as input the…

Genomics · Quantitative Biology 2023-03-22 Yannis Papanikolaou , Francesco Tuveri , Misa Ogura , Daniel O'Donovan

The intricate relationship between genetic variation and human diseases has been a focal point of medical research, evidenced by the identification of risk genes regarding specific diseases. The advent of advanced genome sequencing…

Quantitative Methods · Quantitative Biology 2024-01-19 Jiayu Chang , Shiyu Wang , Chen Ling , Zhaohui Qin , Liang Zhao

Identification of plant disease is usually done through visual inspection or during laboratory examination which causes delays resulting in yield loss by the time identification is complete. On the other hand, complex deep learning models…

Computer Vision and Pattern Recognition · Computer Science 2021-02-10 Nisar Ahmed , Hafiz Muhammad Shahzad Asif , Gulshan Saleem

In recent years, significant progress has been made in the field of learning from positive and unlabeled examples (PU learning), particularly in the context of advancing image and text classification tasks. However, applying PU learning to…

Image and Video Processing · Electrical Eng. & Systems 2024-05-08 Yan Zhang , Chun Li , Zhaoxia Liu , Ming Li

Understanding the relationships between biomedical terms like viruses, drugs, and symptoms is essential in the fight against diseases. Many attempts have been made to introduce the use of machine learning to the scientific process of…

Machine Learning · Computer Science 2024-03-14 Uchenna Akujuobi , Jun Chen , Mohamed Elhoseiny , Michael Spranger , Xiangliang Zhang

This paper proposes a novel pseudo-labeling method for medical image segmentation that can perform learning on ``individual images'' to select effective pseudo-labels. We introduce Positive and Unlabeled Learning (PU learning), which uses…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Takehiro Yamane , Itaru Tsuge , Susumu Saito , Ryoma Bise

Deep neural networks (DNNs) achieve state-of-the-art results in a variety of domains. Unfortunately, DNNs are notorious for their non-interpretability, and thus limit their applicability in hypothesis-driven domains such as biology and…

Machine Learning · Computer Science 2018-03-12 Chun-Hao Chang , Ladislav Rampasek , Anna Goldenberg

We propose a new method of learning from positive and unlabeled (PU) examples in highly imbalanced datasets. Many real-world problems, such as disease gene identification, targeted marketing, fraud detection, and recommender systems, are…

Machine Learning · Computer Science 2026-05-15 Elias Zavitsanos , Georgios Paliouras

Clinical text classification is an important problem in medical natural language processing. Existing studies have conventionally focused on rules or knowledge sources-based feature engineering, but only a few have exploited effective…

Computation and Language · Computer Science 2018-07-23 Liang Yao , Chengsheng Mao , Yuan Luo

Background: Predictive, stable and interpretable gene signatures are generally seen as an important step towards a better personalized medicine. During the last decade various methods have been proposed for that purpose. However, one…

Genomics · Quantitative Biology 2013-05-28 Yupeng Cun , Holger Fröhlich