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Related papers: Optimising experimental design in neutron reflecto…

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An approach based on the Fisher information (FI) is developed to quantify the maximum information gain and optimal experimental design in neutron reflectometry experiments. In these experiments, the FI can be analytically calculated and…

Data Analysis, Statistics and Probability · Physics 2021-08-03 James H. Durant , Lucas Wilkins , Keith Butler , Joshaniel F. K. Cooper

Using molecular simulation to aid in the analysis of neutron reflectometry measurements is commonplace. However, reflectometry is a tool to probe large-scale structures, and therefore the use of all-atom simulation may be irrelevant. This…

In the past decade, several neutron reflectometry methods for determining the modulus and phase of the complex reflection coefficient of an unknown multilayer thin film have been worked out among which the method of variation of…

Materials Science · Physics 2012-09-06 Seyed Farhad Masoudi , Saeed S. Jahromi

The paper develops methods to construct a one-stage optimal design of dilution experiments under the total available volume constraint typical for bio-medical applications. We consider various design criteria based on the Fisher information…

Statistics Theory · Mathematics 2013-05-08 Maryam Zolghadr , Sergei Zuyev

The quality of numerical reconstructions for unknown parameters in inverse problems depends fundamentally on the selection of experimental data. To ensure a robust reconstruction, it is crucial to select data that are sensitive to the…

Numerical Analysis · Mathematics 2026-04-14 Kathrin Hellmuth , Christian Klingenberg , Qin Li

Neutron and X-ray reflectometry are powerful techniques facilitating the study of the structure of interfacial materials. The analysis of these techniques is ill-posed in nature requiring the application of a model-dependent methods. This…

Soft Condensed Matter · Physics 2022-07-22 Andrew R. McCluskey , Thomas Arnold , Joshaniel F. K. Cooper , Tim Snow

Neutron reflectometry is a critical tool for investigating the structure of thin films and interfaces. However, the misapplication of the Born approximation to reflection geometry leads some to assume that the minimum thickness that may be…

Soft Condensed Matter · Physics 2024-03-21 Nicolas Shiaelis , Luke A. Clifton , Andrew R. McCluskey

Coherent diffractive imaging (CDI) is widely used to characterize structured samples from measurements of diffracting intensity patterns. We introduce a numerical framework to quantify the precision that can be achieved when estimating any…

Optics · Physics 2021-01-08 Dorian Bouchet , Jacob Seifert , Allard P. Mosk

Microwave power absorption by a two-layer system deposited on a metallic surface has been studied in the experimental setup emulating the response to a radar signal. Layers containing hexaferrite and iron powder in a dried paint of…

One of the key challenges in performing muon experiments is knowing which temperatures and applied fields to measure at, and how many muon decays should be measured at each temperature/field combination to get the most useful dataset. We…

High Energy Physics - Experiment · Physics 2025-11-12 Alex Sampson , Peter J. Baker , Lucas Wilkins , John M. Wilkinson

Recently it has been shown that the modules and phase of complex reflection coefficient can be determined by using a magnetic substrate and polarized neutrons. Several other methods have also been worked out based on measurement of…

Materials Science · Physics 2015-05-30 S. Farhad Masoudi , Saeed S. Jahromi

Spectroscopy detected in the time domain entails many techniques, such as FTIR, pump-probe, FT-Raman, and 2DES, and applications, such as molecule characterization, excited state dynamics studies, or spectra classifications. Surprisingly,…

Optics · Physics 2024-05-21 Luca Bolzonello , Niek F van Hulst , Andreas Jakobsson

Reflectometry is a technique that uses the light reflected by a sample to determine properties of the sample. Interferometric reflectometry uses interference between two beams, one of which is incident on ---and reflected back by--- a…

Optics · Physics 2019-10-10 Alexander Nahmad-Rohen , Wolfgang Langbein

Quantum systems used for metrology can offer enhanced precision over their classical counterparts. The design of quantum sensors can be optimized by maximizing the quantum Fisher information (QFI), which characterizes the precision of…

Quantum Physics · Physics 2025-08-26 George Mihailescu , Anthony Kiely , Andrew K. Mitchell

The Liquids Reflectometer at Oak Ridge National Laboratory provides neutron reflectivity capability for an average of about 30 experiments each year. In recent years, there has been a large effort to streamline the data processing and…

Data Analysis, Statistics and Probability · Physics 2017-10-19 Mathieu Doucet , Ricardo Miguel Ferraz Leal , Tanner C. Hobson

The detection of spatial or temporal variations in very thin samples has important applications in the biological sciences. For example, cellular membranes exhibit changes in lipid composition and order, which in turn modulate their…

Neutron reflectometry (NR) has emerged as a unique technique for the investigation of structure and magnetism of thin films of both biologically relevant and magnetic materials. The advantage of NR with respect to many other…

Materials Science · Physics 2023-03-24 Surendra Singh

Interpreting measurements requires a physical theory, but the theory's accuracy may vary across the experimental domain. To optimize experimental design, and so to ensure that the substantial resources necessary for modern experiments are…

We present a Fisher-information (FI) framework for photon-efficient fluorescence lifetime imaging microscopy (FLIM) that treats temporal sampling as a controllable design variable under a fixed photon (dose) budget. Starting from a Poisson…

Instrumentation and Detectors · Physics 2026-01-05 J. Sumaya-Martinez , E. Torres-Garcia

Polarized neutron reflectometry is a powerful technique to interrogate the structures of multilayered magnetic materials with depth sensitivity and nanometer resolution. However, reflectometry profiles often inhabit a complicated objective…

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