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In this study, we develop a physics-informed deep learning-based method to synthesize multiple brain magnetic resonance imaging (MRI) contrasts from a single five-minute acquisition and investigate its ability to generalize to arbitrary…

Statistical shape modeling is the computational process of discovering significant shape parameters from segmented anatomies captured by medical images (such as MRI and CT scans), which can fully describe subject-specific anatomy in the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Krithika Iyer , Shireen Elhabian

Purpose: To develop a self-supervised scan-specific deep learning framework for reconstructing accelerated multiparametric quantitative MRI (qMRI). Methods: We propose REFINE-MORE (REference-Free Implicit NEural representation with MOdel…

Medical Physics · Physics 2025-08-05 Ruimin Feng , Albert Jang , Xingxin He , Fang Liu

Magnetic Resonance Imaging (MRI) is a noninvasive imaging technique that provides excellent soft-tissue contrast without using ionizing radiation. MRI's clinical application may be limited by long data acquisition time; therefore, MR image…

Image and Video Processing · Electrical Eng. & Systems 2020-12-11 Shen Zhao , Lee C. Potter , Rizwan Ahmad

Self-supervised deep learning has accelerated 2D natural image analysis but remains difficult to translate into 3D MRI, where data are scarce and pre-trained 2D backbones cannot capture volumetric context. We present a…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Liam Chalcroft , Jenny Crinion , Cathy J. Price , John Ashburner

Tools, models and statistical methods for signal processing and medical image analysis and training deep learning models to create research prototypes for eventual clinical applications are of special interest to the biomedical imaging…

Image and Video Processing · Electrical Eng. & Systems 2023-12-22 Pratik Shah , Jenna Lester , Jana G Deflino , Vinay Pai

Deep learning techniques have led to state-of-the-art image super resolution with natural images. Normally, pairs of high-resolution and low-resolution images are used to train the deep learning models. These techniques have also been…

Image and Video Processing · Electrical Eng. & Systems 2022-10-14 Yutaro Iwamoto , Kyohei Takeda , Yinhao Li , Akihiko Shiino , Yen-Wei Chen

In the last years, the design of image reconstruction methods in the field of quantitative Magnetic Resonance Imaging (qMRI) has experienced a paradigm shift. Often, when dealing with (quantitative) MR image reconstruction problems, one is…

Optimization and Control · Mathematics 2024-03-01 Andreas Kofler , Felix Frederik Zimmermann , Kostas Papafitsoros

Large-scale medical studies such as the UK Biobank examine thousands of volunteer participants with medical imaging techniques. Combined with the vast amount of collected metadata, anatomical information from these images has the potential…

Image and Video Processing · Electrical Eng. & Systems 2021-05-18 Taro Langner , Robin Strand , Håkan Ahlström , Joel Kullberg

Deep learning-based 3-dimensional (3D) shape reconstruction from 2-dimensional (2D) magnetic resonance imaging (MRI) has become increasingly important in medical disease diagnosis, treatment planning, and computational modeling. This review…

Machine Learning · Computer Science 2025-10-03 Emma McMillian , Abhirup Banerjee , Alfonso Bueno-Orovio

Following the success of deep learning in a wide range of applications, neural network-based machine learning techniques have received interest as a means of accelerating magnetic resonance imaging (MRI). A number of ideas inspired by deep…

Signal Processing · Electrical Eng. & Systems 2019-04-03 Florian Knoll , Kerstin Hammernik , Chi Zhang , Steen Moeller , Thomas Pock , Daniel K. Sodickson , Mehmet Akcakaya

Quantitative susceptibility mapping (QSM) is a useful magnetic resonance imaging (MRI) technique which provides spatial distribution of magnetic susceptibility values of tissues. QSMs can be obtained by deconvolving the dipole kernel from…

Computer Vision and Pattern Recognition · Computer Science 2020-12-08 Gyutaek Oh , Hyokyoung Bae , Hyun-Seo Ahn , Sung-Hong Park , Jong Chul Ye

Video microscopy has a long history of providing insights and breakthroughs for a broad range of disciplines, from physics to biology. Image analysis to extract quantitative information from video microscopy data has traditionally relied on…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Benjamin Midtvedt , Saga Helgadottir , Aykut Argun , Jesús Pineda , Daniel Midtvedt , Giovanni Volpe

Extracting reliable and quantitative microstructure information of living tissue by non-invasive imaging is an outstanding challenge for understanding disease mechanisms and allowing early stage diagnosis of pathologies. Magnetic Resonance…

Medical Physics · Physics 2021-07-12 Milena Capiglioni , Analia Zwick , Pablo Jimenez , Gonzalo A. Alvarez

Current state-of-the-art reconstruction for quantitative tissue maps from fast, compressive, Magnetic Resonance Fingerprinting (MRF), use supervised deep learning, with the drawback of requiring high-fidelity ground truth tissue map…

Image and Video Processing · Electrical Eng. & Systems 2022-11-24 Ketan Fatania , Kwai Y. Chau , Carolin M. Pirkl , Marion I. Menzel , Peter Hall , Mohammad Golbabaee

In this work, we propose a realistic, physics-aware motion simulation procedure for T2*-weighted magnetic resonance imaging (MRI) to improve learning-based motion correction. As T2*-weighted MRI is highly sensitive to motion-related changes…

Image and Video Processing · Electrical Eng. & Systems 2023-10-17 Hannah Eichhorn , Kerstin Hammernik , Veronika Spieker , Samira M. Epp , Daniel Rueckert , Christine Preibisch , Julia A. Schnabel

Quantitative Susceptibility Mapping is a parametric imaging technique to estimate the magnetic susceptibilities of biological tissues from MRI phase measurements. This problem of estimating the susceptibility map is ill posed. Regularized…

Image and Video Processing · Electrical Eng. & Systems 2022-10-14 Arvind Balachandrasekaran , Davood Karimi , Camilo Jaimes , Ali Gholipour

Conventional Magnetic Resonance Imaging (MRI) is hampered by long scan times and only qualitative image contrasts that prohibit a direct comparison between different systems. To address these limitations, model-based reconstructions…

Image and Video Processing · Electrical Eng. & Systems 2022-10-24 Xiaoqing Wang , Zhengguo Tan , Nick Scholand , Volkert Roeloffs , Martin Uecker

Recovering the T2 distribution from multi-echo T2 magnetic resonance (MR) signals is challenging but has high potential as it provides biomarkers characterizing the tissue micro-structure, such as the myelin water fraction (MWF). In this…

Functional magnetic resonance imaging (fMRI) based image reconstruction plays a pivotal role in decoding human perception, with applications in neuroscience and brain-computer interfaces. While recent advancements in deep learning and…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Weiyu Guo , Guoying Sun , JianXiang He , Tong Shao , Shaoguang Wang , Ziyang Chen , Meisheng Hong , Ying Sun , Hui Xiong