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Magnetic resonance imaging (MRI) is a cornerstone of clinical neuroimaging, yet conventional MRIs provide qualitative information heavily dependent on scanner hardware and acquisition settings. While quantitative MRI (qMRI) offers intrinsic…

Quantitative MRI is highly desirable in terms of intrinsic tissue parameters such as T1, T2 and proton density. This approach promises to minimize diagnostic variability and differentiate normal and pathological tissues by comparing tissue…

Medical Physics · Physics 2018-06-21 Qing Lyu , Ge Wang

Magnetic Resonance Fingerprinting (MRF) and other highly accelerated transient-state parameter mapping techniques enable simultaneous quantification of multiple tissue properties, but often suffer from aliasing artifacts due to compressed…

In the field of quantitative imaging, the image information at a pixel or voxel in an underlying domain entails crucial information about the imaged matter. This is particularly important in medical imaging applications, such as…

Optimization and Control · Mathematics 2024-04-12 Guozhi Dong , Moritz Flaschel , Michael Hintermüller , Kostas Papafitsoros , Clemens Sirotenko , Karsten Tabelow

We propose a deep learning-based approach that integrates MRI sequence parameters to improve the accuracy and generalizability of quantitative image synthesis from clinical weighted MRI. Our physics-driven neural network embeds MRI sequence…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Lingjing Chen , Chengxiu Zhang , Yinqiao Yi , Yida Wang , Yang Song , Xu Yan , Shengfang Xu , Dalin Zhu , Mengqiu Cao , Yan Zhou , Chenglong Wang , Guang Yang

Quantitative Magnetic Resonance Imaging (MRI) is based on a two-steps approach: estimation of the magnetic moments distribution inside the body, followed by a voxel-by-voxel quantification of the human tissue properties. This splitting…

Quantitative MRI (qMRI) offers significant advantages over weighted images by providing objective parameters related to tissue properties. Deep learning-based methods have demonstrated effectiveness in estimating quantitative maps from…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Shishuai Wang , Hua Ma , Juan A. Hernandez-Tamames , Stefan Klein , Dirk H. J. Poot

The task of MRI fingerprinting is to identify tissue parameters from complex-valued MRI signals. The prevalent approach is dictionary based, where a test MRI signal is compared to stored MRI signals with known tissue parameters and the most…

Computer Vision and Pattern Recognition · Computer Science 2017-07-04 Patrick Virtue , Stella X. Yu , Michael Lustig

Quantitative susceptibility mapping (QSM) utilizes MRI signal phase to infer estimates of local tissue magnetism (magnetic susceptibility), which has been shown useful to provide novel image contrast and as biomarkers of abnormal tissue.…

Medical Physics · Physics 2019-04-16 Juan Liu , Kevin M. Koch

Quantitative Magnetic Resonance Imaging (qMRI) provides researchers insight into pathological and physiological alterations of living tissue, with the help of which researchers hope to predict (local) therapeutic efficacy early and…

Applications · Statistics 2008-07-30 Xiaoxi Zhang , Timothy D. Johnson , Roderick J. A. Little , Yue Cao

Obtaining magnetic resonance images (MRI) with high resolution and generating quantitative image-based biomarkers for assessing tissue biochemistry is crucial in clinical and research applications. How- ever, acquiring quantitative…

Computer Vision and Pattern Recognition · Computer Science 2018-08-15 Akshay Chaudhari , Zhongnan Fang , Jin Hyung Lee , Garry Gold , Brian Hargreaves

Magnetic Resonance Imaging (MRI) is a principal diagnostic approach used in the field of radiology to create images of the anatomical and physiological structure of patients. MRI is the prevalent medical imaging practice to find…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Yusuf Brima , Mossadek Hossain Kamal Tushar , Upama Kabir , Tariqul Islam

Quantitative susceptibility mapping (QSM) has gained broad interests in the field by extracting biological tissue properties, predominantly myelin, iron and calcium from magnetic resonance imaging (MRI) phase measurements in vivo. Thereby,…

Image and Video Processing · Electrical Eng. & Systems 2019-12-12 Woojin Jung , Steffen Bollmann , Jongho Lee

This paper proposes a novel self-supervised learning method, RELAX-MORE, for quantitative MRI (qMRI) reconstruction. The proposed method uses an optimization algorithm to unroll a model-based qMRI reconstruction into a deep learning…

Biological Physics · Physics 2023-07-26 Wanyu Bian , Albert Jang , Fang Liu

Quantitative MRI (qMRI) methods allow reducing the subjectivity of clinical MRI by providing numerical values on which diagnostic assessment or predictions of tissue properties can be based. However, qMRI measurements typically take more…

Medical Physics · Physics 2022-02-15 Matti Hanhela , Antti Paajanen , Mikko J. Nissi , Ville Kolehmainen

Quantitative magnetic resonance imaging (qMRI) offers tissue-specific physical parameters with significant potential for neuroscience research and clinical practice. However, lengthy scan times for 3D multiparametric qMRI acquisition limit…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Guoyan Lao , Ruimin Feng , Haikun Qi , Zhenfeng Lv , Qiangqiang Liu , Chunlei Liu , Yuyao Zhang , Hongjiang Wei

Quantitative MRI (qMRI) estimates tissue properties of interest from measured MRI signals. This process is conventionally achieved by model fitting, whose computational expense limits qMRI's clinical use, motivating recent development of…

Medical Physics · Physics 2025-10-10 Giulio V. Minore , Louis Dwyer-Hemmings , Timothy J. P. Bray , Hui Zhang

Quantitative MRI (qMRI) refers to a class of MRI methods for quantifying the spatial distribution of biological tissue parameters. Traditional qMRI methods usually deal separately with artifacts arising from accelerated data acquisition,…

Image and Video Processing · Electrical Eng. & Systems 2025-02-21 Xiaojian Xu , Weijie Gan , Satya V. V. N. Kothapalli , Dmitriy A. Yablonskiy , Ulugbek S. Kamilov

Quantitative magnetic resonance imaging (qMRI) is concerned with estimating (in physical units) values of magnetic and tissue parameters e.g., relaxation times $T_1$, $T_2$, or proton density $\rho$. Recently in [Ma et al., Nature, 2013],…

Optimization and Control · Mathematics 2019-03-29 Guozhi Dong , Michael Hintermüller , Kostas Papafitsoros

The diagnosis, prognosis, and treatment of patients with musculoskeletal (MSK) disorders require radiology imaging (using computed tomography, magnetic resonance imaging(MRI), and ultrasound) and their precise analysis by expert…

Image and Video Processing · Electrical Eng. & Systems 2020-03-03 Ismail Irmakci , Syed Muhammad Anwar , Drew A. Torigian , Ulas Bagci
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