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Federated learning enables multiple hospitals to cooperatively learn a shared model without privacy disclosure. Existing methods often take a common assumption that the data from different hospitals have the same modalities. However, such a…

Image and Video Processing · Electrical Eng. & Systems 2023-06-06 Yunlu Yan , Hong Wang , Yawen Huang , Nanjun He , Lei Zhu , Yuexiang Li , Yong Xu , Yefeng Zheng

Protein-ligand binding affinity (PLBA) prediction is the fundamental task in drug discovery. Recently, various deep learning-based models predict binding affinity by incorporating the three-dimensional structure of protein-ligand complexes…

Biomolecules · Quantitative Biology 2023-12-21 Jiaxian Yan , Zhaofeng Ye , Ziyi Yang , Chengqiang Lu , Shengyu Zhang , Qi Liu , Jiezhong Qiu

Collaborative filtering-based recommender systems that rely on a single type of behavior often encounter serious sparsity issues in real-world applications, leading to unsatisfactory performance. Multi-behavior Recommendation (MBR) is a…

Information Retrieval · Computer Science 2023-06-21 Mingshi Yan , Zhiyong Cheng , Jing Sun , Fuming Sun , Yuxin Peng

Accurate prediction of recurrence in clear cell renal cell carcinoma (ccRCC) remains a major clinical challenge due to the disease complex molecular, pathological, and clinical heterogeneity. Traditional prognostic models, which rely on…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Hasaan Maqsood , Saif Ur Rehman Khan

Large-scale population-based studies in medicine are a key resource towards better diagnosis, monitoring, and treatment of diseases. They also serve as enablers of clinical decision support systems, in particular Computer Aided Diagnosis…

Machine Learning · Computer Science 2022-03-01 Gerome Vivar , Anees Kazi , Hendrik Burwinkel , Andreas Zwergal , Nassir Navab , Seyed-Ahmad Ahmadi

Recent advancements in the acquisition of various brain data sources have created new opportunities for integrating multimodal brain data to assist in early detection of complex brain disorders. However, current data integration approaches…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Reza Shirkavand , Liang Zhan , Heng Huang , Li Shen , Paul M. Thompson

Multimodal fusion leverages information across modalities to learn better feature representations with the goal of improving performance in fusion-based tasks. However, multimodal datasets, especially in medical settings, are typically…

Machine Learning · Computer Science 2025-02-05 Alejandro Guerra-Manzanares , Farah E. Shamout

This work focuses on learning useful and robust deep world models using multiple, possibly unreliable, sensors. We find that current methods do not sufficiently encourage a shared representation between modalities; this can cause poor…

Machine Learning · Computer Science 2021-07-07 Kaiqi Chen , Yong Lee , Harold Soh

The lack of interpretability in the field of medical image analysis has significant ethical and legal implications. Existing interpretable methods in this domain encounter several challenges, including dependency on specific models,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Lijie Hu , Songning Lai , Wenshuo Chen , Hongru Xiao , Hongbin Lin , Lu Yu , Jingfeng Zhang , Di Wang

Neurons have a polarized structure, including dendrites and axons, and compartment-specific functions can be affected by dwelling mitochondria. It is known that the morphology of mitochondria is closely related to the functions of neurons…

Computer Vision and Pattern Recognition · Computer Science 2021-09-06 JunYoung Choi , Hakjun Lee , Suyeon Kim , Seok-Kyu Kwon , Won-Ki Jeong

In human neuroscience, machine learning can help reveal lower-dimensional neural representations relevant to subjects' behavior. However, state-of-the-art models typically require large datasets to train, so are prone to overfitting on…

Multi-modal brain functional connectivity (FC) data have shown great potential for providing insights into individual variations in behavioral and cognitive traits. The joint learning of multi-modal imaging data can utilize the intrinsic…

Quantitative Methods · Quantitative Biology 2019-01-18 Li Xiao , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu-Ping Wang

Recently, Graph Convolutional Networks (GCNs) have proven to be a powerful mean for Computer Aided Diagnosis (CADx). This approach requires building a population graph to aggregate structural information, where the graph adjacency matrix…

Artificial Intelligence · Computer Science 2021-06-17 Hao Chen , Fuzhen Zhuang , Li Xiao , Ling Ma , Haiyan Liu , Ruifang Zhang , Huiqin Jiang , Qing He

The prediction of subjects with mild cognitive impairment (MCI) who will progress to Alzheimer's disease (AD) is clinically relevant, and may above all have a significant impact on accelerate the development of new treatments. In this…

Image and Video Processing · Electrical Eng. & Systems 2019-07-16 Kilian Hett , Vinh-Thong Ta , José V. Manjón , Pierrick Coupé

The main goal of the multitasking optimization paradigm is to solve multiple and concurrent optimization tasks in a simultaneous way through a single search process. For attaining promising results, potential complementarities and synergies…

Neural and Evolutionary Computing · Computer Science 2020-10-01 Eneko Osaba , Esther Villar-Rodriguez , Javier Del Ser

Accurate diagnosis and treatment of complex diseases require integrating histological, molecular, and clinical data, yet in practice these modalities are often incomplete owing to tissue scarcity, assay cost, and workflow constraints.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Jinxi Xiang , Mingjie Li , Siyu Hou , Yijiang Chen , Xiangde Luo , Yuanfeng Ji , Xiang Zhou , Ehsan Adeli , Akshay Chaudhari , Curtis P. Langlotz , Kilian M. Pohl , Ruijiang Li

The computer-aided disease diagnosis from radiomic data is important in many medical applications. However, developing such a technique relies on annotating radiological images, which is a time-consuming, labor-intensive, and expensive…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Zhiyuan Li , Hailong Li , Anca L. Ralescu , Jonathan R. Dillman , Nehal A. Parikh , Lili He

Clinical research often focuses on complex traits in which many variables play a role in mechanisms driving, or curing, diseases. Clinical prediction is hard when data is high-dimensional, but additional information, like domain knowledge…

Methodology · Statistics 2020-05-21 Mirrelijn M. van Nee , Lodewyk F. A. Wessels , Mark A. van de Wiel

We present MultiCheXNet, an end-to-end Multi-task learning model, that is able to take advantage of different X-rays data sets of Pneumonia-like diseases in one neural architecture, performing three tasks at the same time; diagnosis,…

Many diagnostic and therapeutic clinical tasks for prostate cancer increasingly rely on multi-parametric MRI. Automating these tasks is challenging because they necessitate expert interpretations, which are difficult to scale to capitalise…

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