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In this paper, we propose a structured feature learning framework to reason the correlations among body joints at the feature level in human pose estimation. Different from existing approaches of modelling structures on score maps or…

Computer Vision and Pattern Recognition · Computer Science 2016-03-31 Xiao Chu , Wanli Ouyang , Hongsheng Li , Xiaogang Wang

We propose probabilistic Shapley inference (PSI), a novel probabilistic framework to model and infer sufficient statistics of feature attributions in flexible predictive models, via latent random variables whose mean recovers Shapley…

Machine Learning · Computer Science 2025-09-09 Mert Ketenci , Iñigo Urteaga , Victor Alfonso Rodriguez , Noémie Elhadad , Adler Perotte

Proteins, as essential biomolecules, play a central role in biological processes, including metabolic reactions and DNA replication. Accurate prediction of their properties and functions is crucial in biological applications. Recent…

Computation and Language · Computer Science 2025-05-30 Wei Wu , Chao Wang , Liyi Chen , Mingze Yin , Yiheng Zhu , Kun Fu , Jieping Ye , Hui Xiong , Zheng Wang

Proteins are the basic building blocks of life. They usually perform functions by folding to a particular structure. Understanding the folding process could help the researchers to understand the functions of proteins and could also help to…

Computational Engineering, Finance, and Science · Computer Science 2015-10-21 Jianzhu Ma

Biometric recognition on partial captured targets is challenging, where only several partial observations of objects are available for matching. In this area, deep learning based methods are widely applied to match these partial captured…

Computer Vision and Pattern Recognition · Computer Science 2018-10-18 Lingxiao He , Zhenan Sun , Yuhao Zhu , Yunbo Wang

Feature selection has been proven a powerful preprocessing step for high-dimensional data analysis. However, most state-of-the-art methods tend to overlook the structural correlation information between pairwise samples, which may…

Machine Learning · Computer Science 2019-07-02 Lu Bai , Lixin Cui , Yue Wang , Philip S. Yu , Edwin R. Hancock

Prior feature transformation based approaches to Unsupervised Domain Adaptation (UDA) employ the deep features extracted by pre-trained deep models without fine-tuning them on the specific source or target domain data for a particular…

Computer Vision and Pattern Recognition · Computer Science 2022-10-26 Qian Wang , Toby P. Breckon

In text recognition, self-supervised pre-training emerges as a good solution to reduce dependence on expansive annotated real data. Previous studies primarily focus on local visual representation by leveraging mask image modeling or…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Zuan Gao , Yuxin Wang , Yadong Qu , Boqiang Zhang , Zixiao Wang , Jianjun Xu , Hongtao Xie

Experimental determination of protein function is resource-consuming. As an alternative, computational prediction of protein function has received attention. In this context, protein structural classification (PSC) can help, by allowing for…

Molecular Networks · Quantitative Biology 2020-03-17 Khalique Newaz , Mahboobeh Ghalehnovi , Arash Rahnama , Panos J. Antsaklis , Tijana Milenkovic

Sparse Autoencoders have emerged as powerful tools for interpreting the internal representations of Large Language Models, yet they often fail to capture domain-specific features not prevalent in their training corpora. This paper…

Machine Learning · Computer Science 2025-07-18 Nikita Koriagin , Yaroslav Aksenov , Daniil Laptev , Gleb Gerasimov , Nikita Balagansky , Daniil Gavrilov

Predicting protein structure from amino acid sequence is one of the most important unsolved problems of molecular biology and biophysics.Not only would a successful prediction algorithm be a tremendous advance in the understanding of the…

Computational Engineering, Finance, and Science · Computer Science 2010-06-15 K. K Senapati , G. Sahoo , D. Bhaumik

Proteins, essential to biological systems, perform functions intricately linked to their three-dimensional structures. Understanding the relationship between protein structures and their amino acid sequences remains a core challenge in…

Quantitative Methods · Quantitative Biology 2024-11-04 Liang He , Peiran Jin , Yaosen Min , Shufang Xie , Lijun Wu , Tao Qin , Xiaozhuan Liang , Kaiyuan Gao , Yuliang Jiang , Tie-Yan Liu

Successive Subspace Learning (SSL) offers a light-weight unsupervised feature learning method based on inherent statistical properties of data units (e.g. image pixels and points in point cloud sets). It has shown promising results,…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 Mozhdeh Rouhsedaghat , Masoud Monajatipoor , Zohreh Azizi , C. -C. Jay Kuo

Semisupervised methods inevitably invoke some assumption that links the marginal distribution of the features to the regression function of the label. Most commonly, the cluster or manifold assumptions are used which imply that the…

Statistics Theory · Mathematics 2011-12-02 Martin Azizyan , Aarti Singh , Larry Wasserman

Plant phenotyping (Guo et al. 2021; Pieruschka et al. 2019) focuses on studying the diverse traits of plants related to the plants' growth. To be more specific, by accurately measuring the plant's anatomical, ontogenetical, physiological…

Machine Learning · Computer Science 2022-01-17 Jun Wu , Elizabeth A. Ainsworth , Sheng Wang , Kaiyu Guan , Jingrui He

Domain adaptation, adapting models from domains rich in labeled training data to domains poor in such data, is a fundamental NLP challenge. We introduce a neural network model that marries together ideas from two prominent strands of…

Computation and Language · Computer Science 2017-06-20 Yftah Ziser , Roi Reichart

Federated learning enables multiple clients (institutions) to collaboratively train machine learning models without sharing their private data. To address the challenge of data heterogeneity across clients, personalized federated learning…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Meilu Zhu , Yuxing Li , Zhiwei Wang , Edmund Y. Lam

High-contrast imaging of exoplanets hinges on powerful post-processing methods to denoise the data and separate the signal of a companion from its host star, which is typically orders of magnitude brighter. Existing post-processing…

Instrumentation and Methods for Astrophysics · Physics 2022-10-05 Timothy D. Gebhard , Markus J. Bonse , Sascha P. Quanz , Bernhard Schölkopf

Compound-Protein Interaction (CPI) prediction aims to predict the pattern and strength of compound-protein interactions for rational drug discovery. Existing deep learning-based methods utilize only the single modality of protein sequences…

Biomolecules · Quantitative Biology 2024-02-14 Lirong Wu , Yufei Huang , Cheng Tan , Zhangyang Gao , Bozhen Hu , Haitao Lin , Zicheng Liu , Stan Z. Li

Intracellular compartmentalization of proteins underpins their function and the metabolic processes they sustain. Various mass spectrometry-based proteomics methods (subcellular spatial proteomics) now allow high throughput subcellular…

Quantitative Methods · Quantitative Biology 2025-12-10 Ziyue Zheng , Loay J. Jabre , Matthew McIlvin , Mak A. Saito , Sangwon Hyun
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