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During training, the weights of a Deep Neural Network (DNN) are optimized from a random initialization towards a nearly optimum value minimizing a loss function. Only this final state of the weights is typically kept for testing, while the…

Machine Learning · Computer Science 2021-03-26 Gianni Franchi , Andrei Bursuc , Emanuel Aldea , Severine Dubuisson , Isabelle Bloch

Accurate segmentation of brain tumors is vital for diagnosis, surgical planning, and treatment monitoring. Deep learning has advanced on benchmarks, but two issues limit clinical use: no uncertainty estimates for errors and no segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Andrew Zhou

Precise 3D segmentation of infant brain tissues is an essential step towards comprehensive volumetric studies and quantitative analysis of early brain developement. However, computing such segmentations is very challenging, especially for…

Computer Vision and Pattern Recognition · Computer Science 2017-12-20 Jose Dolz , Christian Desrosiers , Li Wang , Jing Yuan , Dinggang Shen , Ismail Ben Ayed

Nonrigid registration is vital to medical image analysis but remains challenging for diffusion MRI (dMRI) due to its high-dimensional, orientation-dependent nature. While classical methods are accurate, they are computationally demanding,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-13 Gianfranco Cortes , Xiaoda Qu , Baba C. Vemuri

Segmentation of the developing fetal brain is an important step in quantitative analyses. However, manual segmentation is a very time-consuming task which is prone to error and must be completed by highly specialized indi-viduals.…

Image and Video Processing · Electrical Eng. & Systems 2020-09-15 Kelly Payette , Raimund Kottke , Andras Jakab

In this paper, we focus on three problems in deep learning based medical image segmentation. Firstly, U-net, as a popular model for medical image segmentation, is difficult to train when convolutional layers increase even though a deeper…

Computer Vision and Pattern Recognition · Computer Science 2018-10-17 Wanli Chen , Yue Zhang , Junjun He , Yu Qiao , Yifan Chen , Hongjian Shi , Xiaoying Tang

Deep neural networks give state-of-the-art accuracy for reconstructing images from few and noisy measurements, a problem arising for example in accelerated magnetic resonance imaging (MRI). However, recent works have raised concerns that…

Image and Video Processing · Electrical Eng. & Systems 2021-06-14 Mohammad Zalbagi Darestani , Akshay S. Chaudhari , Reinhard Heckel

We propose a framework for distributed robust statistical learning on {\em big contaminated data}. The Distributed Robust Learning (DRL) framework can reduce the computational time of traditional robust learning methods by several orders of…

Machine Learning · Statistics 2015-02-10 Jiashi Feng , Huan Xu , Shie Mannor

Automatic brain tumor segmentation from Magnetic Resonance Imaging (MRI) data plays an important role in assessing tumor response to therapy and personalized treatment stratification.Manual segmentation is tedious and…

Image and Video Processing · Electrical Eng. & Systems 2021-11-29 Hadas Ben-Atya , Ori Rajchert , Liran Goshen , Moti Freiman

The recent achievements of Deep Learning rely on the test data being similar in distribution to the training data. In an ideal case, Deep Learning models would achieve Out-of-Distribution (OoD) Generalization, i.e. reliably make predictions…

Image and Video Processing · Electrical Eng. & Systems 2021-09-07 Antoine Sanner , Camila Gonzalez , Anirban Mukhopadhyay

Deep-learning-based segmentation algorithms have substantially advanced the field of medical image analysis, particularly in structural delineations in MRIs. However, an important consideration is the intrinsic bias in the data. Concerns…

Computer Vision and Pattern Recognition · Computer Science 2026-02-23 Ghazal Danaee , Marc Niethammer , Jarrett Rushmore , Sylvain Bouix

Accurate segmentation of the left atrium (LA) from cardiac MRI is critical for guiding atrial fibrillation (AF) ablation and constructing biophysical cardiac models. Manual delineation is time-consuming, observer-dependent, and impractical…

Image and Video Processing · Electrical Eng. & Systems 2025-11-08 Fatemeh Hosseinabadi , Seyedhassan Sharifi

Deep convolutional neural networks (CNNs) are state-of-the-art for semantic image segmentation, but typically require many labeled training samples. Obtaining 3D segmentations of medical images for supervised training is difficult and labor…

Computer Vision and Pattern Recognition · Computer Science 2019-07-29 Zhenlin Xu , Marc Niethammer

We present a novel approach to automatically segment magnetic resonance (MR) images of the human brain into anatomical regions. Our methodology is based on a deep artificial neural network that assigns each voxel in an MR image of the brain…

Computer Vision and Pattern Recognition · Computer Science 2015-06-26 Alexandre de Brebisson , Giovanni Montana

Most of the current state-of-the-art methods for tumor segmentation are based on machine learning models trained on manually segmented images. This type of training data is particularly costly, as manual delineation of tumors is not only…

Computer Vision and Pattern Recognition · Computer Science 2019-08-21 Pawel Mlynarski , Hervé Delingette , Antonio Criminisi , Nicholas Ayache

Uncertainty quantification is vital for safety-critical Deep Learning applications like medical image segmentation. We introduce BA U-Net, an uncertainty-aware model for MRI segmentation that integrates Bayesian Neural Networks with…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Lohith Konathala

Diffusion-weighted MRI is increasingly used to study the normal and abnormal development of fetal brain in-utero. Recent studies have shown that dMRI can offer invaluable insights into the neurodevelopmental processes in the fetal stage.…

Although distributed machine learning has opened up many new and exciting research frontiers, fragmentation of models and data across different machines, nodes, and sites still results in considerable communication overhead, impeding…

Machine Learning · Computer Science 2022-02-04 Bradley T. Baker , Aashis Khanal , Vince D. Calhoun , Barak Pearlmutter , Sergey M. Plis

Segmentation of microscopy images constitutes an ill-posed inverse problem due to measurement noise, weak object boundaries, and limited labeled data. Although deep neural networks provide flexible nonparametric estimators, unconstrained…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Seema K. Poudel , Sunny K. Khadka

This monograph develops a comprehensive statistical learning framework that is robust to (distributional) perturbations in the data using Distributionally Robust Optimization (DRO) under the Wasserstein metric. Beginning with fundamental…

Machine Learning · Statistics 2021-08-23 Ruidi Chen , Ioannis Ch. Paschalidis
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