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Localizing neuronal activity in the brain, both in time and in space, is a central challenge to advance the understanding of brain function. Because of the inability of any single neuroimaging techniques to cover all aspects at once, there…

Neurons and Cognition · Quantitative Biology 2013-07-09 Yaroslav O. Halchenko , Michael Hanke , James V. Haxby , Stephen Jose Hanson , Christoph S. Herrmann

Ischemic brain injuries are frequent and difficult to detect reliably or early. We present the multi-modal data set containing cardiovascular (blood pressure, blood flow, electrocardiogram) and brain electrical activities to derive…

Quantitative Methods · Quantitative Biology 2021-02-26 Martin G. Frasch , Bernd Walter , Christophe L. Herry , Reinhard Bauer

The realisation of precision cardiology requires novel techniques for the non-invasive characterisation of individual patients' cardiac function to inform therapeutic and diagnostic decision-making. The electrocardiogram (ECG) is the most…

Tissues and Organs · Quantitative Biology 2021-12-09 Julia Camps , Brodie Lawson , Christopher Drovandi , Ana Minchole , Zhinuo Jenny Wang , Vicente Grau , Kevin Burrage , Blanca Rodriguez

We introduce Multivariate Multiscale Graph-based Dispersion Entropy (mvDEG), a novel, computationally efficient method for analyzing multivariate time series data in graph and complex network frameworks, and demonstrate its application in…

Combinatorics · Mathematics 2024-05-02 John Stewart Fabila-Carrasco , Chao Tan , Javier Escudero

Robust characterization of dynamic causal interactions in multivariate biomedical signals is essential for advancing computational and algorithmic methods in biomedical imaging. Conventional approaches, such as Dynamic Bayesian Networks…

Signal Processing · Electrical Eng. & Systems 2026-02-17 Farwa Abbas , Wei Dai , Zoran Cvetkovic , Verity McClelland

Subcortical structures play a critical role in brain function. However, options for assessing electrophysiological activity in these structures are limited. Electromagnetic fields generated by neuronal activity in subcortical structures can…

Imbalanced electrocardiogram (ECG) data hampers the efficacy and resilience of algorithms in the automated processing and interpretation of cardiovascular diagnostic information, which in turn impedes deep learning-based ECG classification.…

Machine Learning · Computer Science 2026-01-15 Haijian Shao , Wei Liu , Xing Deng , Daze Lu

Transcranial electric stimulation (TES) can modulate intrinsic neural activity in the brain by injecting weak currents through electrodes attached to the scalp. TES has been widely used as a neuroscience tool to investigate how behavioural…

Current non-invasive neuroimaging techniques trade off between spatial resolution and temporal resolution. While magnetoencephalography (MEG) can capture rapid neural dynamics and functional magnetic resonance imaging (fMRI) can spatially…

Neurons and Cognition · Quantitative Biology 2025-10-13 Beige Jerry Jin , Leila Wehbe

Knowledge graph embedding, which aims to learn the low-dimensional representations of entities and relationships, has attracted considerable research efforts recently. However, most knowledge graph embedding methods focus on the structural…

Machine Learning · Computer Science 2020-07-23 Yonghui Xu , Shengjie Sun , Yuan Miao , Dong Yang , Xiaonan Meng , Yi Hu , Ke Wang , Hengjie Song , Chuanyan Miao

This work presents a novel framework for time series analysis using entropic measures based on the kernel density estimate (KDE) of the time series' Takens' embeddings. Using this framework we introduce two distinct analytical tools: (1) a…

Information Theory · Computer Science 2025-12-05 Audun Myers , Bill Kay , Iliana Alvarez , Michael Hughes , Cameron Mackenzie , Carlos Ortiz Marrero , Emily Ellwein , Erik Lentz

Human emotions are difficult to convey through words and are often abstracted in the process; however, electroencephalogram (EEG) signals can offer a more direct lens into emotional brain activity. Recent studies show that deep learning…

Neurons and Cognition · Quantitative Biology 2025-11-19 Nilay Kumar , Priyansh Bhandari , G. Maragatham

Intracellular processes triggered by neural activity include changes in ionic concentrations, protein release, and synaptic vesicle cycling. These processes play significant roles in neurological disorders. The beneficial effects of brain…

Neurons and Cognition · Quantitative Biology 2024-09-26 Saeed Omidi , Gianluca Fabi , Xiaopeng Wang , James C. M. Hwang , Yevgeny Berdichevsky

Intracranial EEG (iEEG) provides high-fidelity neural recordings essential for clinical and brain-computer interface applications, but acquiring these signals requires invasive surgery. While recent studies have attempted to estimate iEEG…

Signal Processing · Electrical Eng. & Systems 2026-05-20 Tien-Dat Pham , Xuan-The Tran

Measuring entanglement entropy in interacting, multipartite systems remains a significant experimental challenge. We address this challenge by developing a protocol to measure von Neumann entropy (VNE) and mutual information in quantum…

Mesoscale and Nanoscale Physics · Physics 2025-08-05 Zhenhua Zhu , Gu Zhang , Dong E. Liu

Cuffless blood pressure (BP) estimation based on Pulse Transit Time (PTT) has emerged as a promising solution for continuous health monitoring. However, conventional models relying on the Moens-Korteweg equation often fail during rapid…

Human-Computer Interaction · Computer Science 2026-05-01 Boyuan Gu , Yijin Yang , Shuaiqi Cheng , Xiaorong Ding

This paper presents a new toolbox for MEEG source activity and connectivity estimation: Brain Connectivity Variable Resolution Tomographic Analysis version 1.0 (BC-VARETA 1.0). It relies on the third generation of nonlinear methods for the…

Neurons and Cognition · Quantitative Biology 2019-12-03 Eduardo Gonzalez-Moreira , Deirel Paz-Linares , Ariosky Areces-Gonzalez , Rigel Wang , Pedro A. Valdes-Sosa

MEG and EEG are noninvasive functional neuroimaging techniques that provide recordings of brain activity with high temporal resolution, and thus provide a unique window to study fast time-scale neural dynamics in humans. However, the…

Applications · Statistics 2015-11-13 Camilo Lamus , Matti S. Hamalainen , Emery N. Brown , Patrick L. Purdon

We address the problem of evaluating the transfer entropy (TE) produced by biochemical reactions from experimentally measured data. Although these reactions are generally non-linear and non-stationary processes making it challenging to…

Electromyography (EMG)--based computational musculoskeletal modeling is a non-invasive method for studying musculotendon function, human movement, and neuromuscular control, providing estimates of internal variables like muscle forces and…

Machine Learning · Computer Science 2025-03-10 Rajnish Kumar , Tapas Tripura , Souvik Chakraborty , Sitikantha Roy
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