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Diffusion magnetic resonance imaging (dMRI) and tractography provide means to study the anatomical structures within the white matter of the brain. When studying tractography data across subjects, it is usually necessary to align, i.e. to…

Machine Learning · Statistics 2016-02-01 Thien Bao Nguyen , Emanuele Olivetti , Paolo Avesani

Cortical surface registration is often driven by local geometric descriptors (e.g., sulcal depth and curvature). While this approach achieves geometric correspondence, it neglects the long-range wiring constraints imposed by white-matter…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Yang Xiang , Martin Cole , Zhengwu Zhang

White matter tractography is an advanced neuroimaging technique that reconstructs the 3D white matter pathways of the brain from diffusion MRI data. It can be framed as a pathfinding problem aiming to infer neural fiber trajectories from…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Itzik Waizman , Yakov Gusakov , Itay Benou , Tammy Riklin Raviv

While the major white matter tracts are of great interest to numerous studies in neuroscience and medicine, their manual dissection in larger cohorts from diffusion MRI tractograms is time-consuming, requires expert knowledge and is hard to…

Computer Vision and Pattern Recognition · Computer Science 2018-06-15 Jakob Wasserthal , Peter F. Neher , Klaus H. Maier-Hein

The individual course of white matter fiber tracts is an important key for analysis of white matter characteristics in healthy and diseased brains. Uniquely, diffusion-weighted MRI tractography in combination with region-based or…

Computer Vision and Pattern Recognition · Computer Science 2018-08-21 Jakob Wasserthal , Peter Neher , Klaus H. Maier-Hein

Brain imaging studies have demonstrated that diffusion MRI tractography geometric shape descriptors can inform the study of the brain's white matter pathways and their relationship to brain function. In this work, we investigate the…

Computer Vision and Pattern Recognition · Computer Science 2025-02-17 Yui Lo , Yuqian Chen , Dongnan Liu , Jon Haitz Legarreta , Leo Zekelman , Fan Zhang , Jarrett Rushmore , Yogesh Rathi , Nikos Makris , Alexandra J. Golby , Weidong Cai , Lauren J. O'Donnell

Parcellation of whole-brain tractography streamlines is an important step for tract-based analysis of brain white matter microstructure. Existing fiber parcellation approaches rely on accurate registration between an atlas and the…

Image and Video Processing · Electrical Eng. & Systems 2019-12-24 Feihong Liu , Jun Feng , Geng Chen , Ye Wu , Yoonmi Hong , Pew-Thian Yap , Dinggang Shen

The brain white matter consists of a set of tracts that connect distinct regions of the brain. Segmentation of these tracts is often needed for clinical and research studies. Diffusion-weighted MRI offers unique contrast to delineate these…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Hamza Kebiri , Ali Gholipour , Meritxell Bach Cuadra , Davood Karimi

White matter tract segmentation is crucial for studying brain structural connectivity and neurosurgical planning. However, segmentation remains challenging due to issues like class imbalance between major and minor tracts, structural…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Anoushkrit Goel , Bipanjit Singh , Ankita Joshi , Ranjeet Ranjan Jha , Chirag Ahuja , Aditya Nigam , Arnav Bhavsar

Registration of diffusion MRI tractography is an essential step for analyzing group similarities and variations in the brain's white matter (WM). Streamline-based registration approaches can leverage the 3D geometric information of fiber…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Junyi Wang , Mubai Du , Ye Wu , Yijie Li , William M. Wells , Lauren J. O'Donnell , Fan Zhang

While the major white matter tracts are of great interest to numerous studies in neuroscience and medicine, their manual dissection in larger cohorts from diffusion MRI tractograms is time-consuming, requires expert knowledge and is hard to…

Computer Vision and Pattern Recognition · Computer Science 2019-09-26 Jakob Wasserthal , Peter Neher , Dusan Hirjak , Klaus H. Maier-Hein

Fiber tractography on diffusion imaging data offers rich potential for describing white matter pathways in the human brain, but characterizing the spatial organization in these large and complex data sets remains a challenge. We show that…

Methodology · Statistics 2015-06-18 Brian P. Kent , Alessandro Rinaldo , Fang-Cheng Yeh , Timothy Verstynen

In the present work, we use information theory to understand the empirical convergence rate of tractography, a widely-used approach to reconstruct anatomical fiber pathways in the living brain. Based on diffusion MRI data, tractography is…

Quantitative Methods · Quantitative Biology 2018-06-13 Daniel Moyer , Paul M. Thompson , Greg Ver Steeg

Tractography from high-dimensional diffusion magnetic resonance imaging (dMRI) data allows brain's structural connectivity analysis. Recent dMRI studies aim to compare connectivity patterns across subject groups and disease populations to…

The brain structural connectome is generated by a collection of white matter fiber bundles constructed from diffusion weighted MRI (dMRI), acting as highways for neural activity. There has been abundant interest in studying how the…

Methodology · Statistics 2022-11-03 Didong Li , Phuc Nguyen , Zhengwu Zhang , David B Dunson

Current brain white matter fiber tracking techniques show a number of problems, including: generating large proportions of streamlines that do not accurately describe the underlying anatomy; extracting streamlines that are not supported by…

Image and Video Processing · Electrical Eng. & Systems 2021-08-03 Jon Haitz Legarreta , Laurent Petit , François Rheault , Guillaume Theaud , Carl Lemaire , Maxime Descoteaux , Pierre-Marc Jodoin

Diffusion-weighted magnetic resonance imaging (dMRI) is widely used to assess the brain white matter. One of the most common computations in dMRI involves cross-subject tract-specific analysis, whereby dMRI-derived biomarkers are compared…

Image and Video Processing · Electrical Eng. & Systems 2023-07-12 Davood Karimi , Hamza Kebiri , Ali Gholipour

Diffusion-weighted magnetic resonance imaging (dMRI) is the only non-invasive tool for studying white matter tracts and structural connectivity of the brain. These assessments rely heavily on tractography techniques, which reconstruct…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Weide Liu , Camilo Calixto , Simon K. Warfield , Davood Karimi

The segregation of brain fiber tractography data into distinct and anatomically meaningful clusters can help to comprehend the complex brain structure and early investigation and management of various neural disorders. We propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2017-10-17 Tushar Gupta , Shreyas Malakarjun Patil , Mukkaram Tailor , Daksh Thapar , Aditya Nigam

We propose a novel and efficient algorithm to model high-level topological structures of neuronal fibers. Tractography constructs complex neuronal fibers in three dimensions that exhibit the geometry of white matter pathways in the brain.…

Computer Vision and Pattern Recognition · Computer Science 2021-08-04 S. Shailja , Angela Zhang , B. S. Manjunath
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