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Deep Learning based models are currently dominating most state-of-the-art solutions for disease prediction. Existing works employ RNNs along with multiple levels of attention mechanisms to provide interpretability. These deep learning…

Machine Learning · Statistics 2022-06-01 Subhadip Maji , Raghav Bali , Sree Harsha Ankem , Kishore V Ayyadevara

Pretraining has proven to be a powerful technique in natural language processing (NLP), exhibiting remarkable success in various NLP downstream tasks. However, in the medical domain, existing pretrained models on electronic health records…

Artificial Intelligence · Computer Science 2023-10-23 Xiaochen Wang , Junyu Luo , Jiaqi Wang , Ziyi Yin , Suhan Cui , Yuan Zhong , Yaqing Wang , Fenglong Ma

Patient representation learning refers to learning a dense mathematical representation of a patient that encodes meaningful information from Electronic Health Records (EHRs). This is generally performed using advanced deep learning methods.…

Machine Learning · Computer Science 2021-01-26 Yuqi Si , Jingcheng Du , Zhao Li , Xiaoqian Jiang , Timothy Miller , Fei Wang , W. Jim Zheng , Kirk Roberts

Deep learning approaches exhibit promising performances on various text tasks. However, they are still struggling on medical text classification since samples are often extremely imbalanced and scarce. Different from existing mainstream…

Computation and Language · Computer Science 2023-11-29 Jiahuan Yan , Haojun Gao , Zhang Kai , Weize Liu , Danny Chen , Jian Wu , Jintai Chen

Despite the growing availability of Electronic Health Record (EHR) data, researchers often face substantial barriers in effectively using these data for translational research due to their complexity, heterogeneity, and lack of standardized…

With the recent availability of Electronic Health Records (EHR) and great opportunities they offer for advancing medical informatics, there has been growing interest in mining EHR for improving quality of care. Disease diagnosis due to its…

Artificial Intelligence · Computer Science 2018-04-24 Anahita Hosseini , Ting Chen , Wenjun Wu , Yizhou Sun , Majid Sarrafzadeh

Latent space models are widely used for analyzing high-dimensional discrete data matrices, such as patient-feature matrices in electronic health records (EHRs), by capturing complex dependence structures through low-dimensional embeddings.…

Machine Learning · Computer Science 2026-02-19 Weijing Tang , Ming Yuan , Zongqi Xia , Tianxi Cai

Deriving disease subtypes from electronic health records (EHRs) can guide next-generation personalized medicine. However, challenges in summarizing and representing patient data prevent widespread practice of scalable EHR-based…

As hospitals move towards automating and integrating their computing systems, more fine-grained hospital operations data are becoming available. These data include hospital architectural drawings, logs of interactions between patients and…

Machine Learning · Computer Science 2023-03-22 Hankyu Jang , Sulyun Lee , D. M. Hasibul Hasan , Philip M. Polgreen , Sriram V. Pemmaraju , Bijaya Adhikari

Electronic Health Records are electronic data generated during or as a byproduct of routine patient care. Structured, semi-structured and unstructured EHR offer researchers unprecedented phenotypic breadth and depth and have the potential…

Artificial Intelligence · Computer Science 2017-07-26 Vaclav Papez , Spiros Denaxas , Harry Hemingway

Objective: Temporal electronic health records (EHRs) can be a wealth of information for secondary uses, such as clinical events prediction or chronic disease management. However, challenges exist for temporal data representation. We…

Machine Learning · Computer Science 2024-06-11 Feng Xie , Han Yuan , Yilin Ning , Marcus Eng Hock Ong , Mengling Feng , Wynne Hsu , Bibhas Chakraborty , Nan Liu

Electronic Health Records (EHRs) enable deep learning for clinical predictions, but the optimal method for representing patient data remains unclear due to inconsistent evaluation practices. We present the first systematic benchmark to…

Machine Learning · Computer Science 2025-10-13 Tianyi Chen , Mingcheng Zhu , Zhiyao Luo , Tingting Zhu

Large Language Models (LLMs) have demonstrated remarkable performance across various domains, including healthcare. However, their ability to effectively represent structured non-textual data, such as the alphanumeric medical codes used in…

We develop an unsupervised probabilistic model for heterogeneous Electronic Health Record (EHR) data. Utilizing a mixture model formulation, our approach directly models sequences of arbitrary length, such as medications and laboratory…

Machine Learning · Computer Science 2022-09-02 Alan D. Kaplan , John D. Greene , Vincent X. Liu , Priyadip Ray

Artificial intelligence (AI) has demonstrated significant potential in transforming healthcare through the analysis and modeling of electronic health records (EHRs). However, the inherent heterogeneity, temporal irregularity, and…

Machine Learning · Computer Science 2025-07-18 Weijieying Ren , Jingxi Zhu , Zehao Liu , Tianxiang Zhao , Vasant Honavar

Automated medical coding, an essential task for healthcare operation and delivery, makes unstructured data manageable by predicting medical codes from clinical documents. Recent advances in deep learning and natural language processing have…

Computation and Language · Computer Science 2024-05-15 Shaoxiong Ji , Wei Sun , Xiaobo Li , Hang Dong , Ara Taalas , Yijia Zhang , Honghan Wu , Esa Pitkänen , Pekka Marttinen

Electronic Health Records (EHR) are high-dimensional data with implicit connections among thousands of medical concepts. These connections, for instance, the co-occurrence of diseases and lab-disease correlations can be informative when…

Machine Learning · Computer Science 2021-03-29 Weicheng Zhu , Narges Razavian

Existing Clinical Decision Support Systems (CDSSs) largely depend on the availability of structured patient data and Electronic Health Records (EHRs) to aid caregivers. However, in case of hospitals in developing countries, structured…

Computation and Language · Computer Science 2019-11-27 Gokul S Krishnan , Sowmya Kamath S

Electronic Health Records (EHR) are data generated during routine clinical care. EHR offer researchers unprecedented phenotypic breadth and depth and have the potential to accelerate the pace of precision medicine at scale. A main EHR…

Quantitative Methods · Quantitative Biology 2017-04-28 Vaclav Papez , Spiros Denaxas , Harry Hemingway

Learning unified text embeddings that excel across diverse downstream tasks is a central goal in representation learning, yet negative transfer remains a persistent obstacle. This challenge is particularly pronounced when jointly training a…

Computation and Language · Computer Science 2025-09-30 Bowen Zhang , Zixin Song , Chunquan Chen , Qian-Wen Zhang , Di Yin , Xing Sun