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The brain constantly turns large flows of sensory information into selective representations of the environment. It, therefore, needs to learn to process those sensory inputs that are most relevant for behaviour. It is not well understood…

Neurons and Cognition · Quantitative Biology 2023-01-10 Pouya Baniasadi

Computational models are an essential tool for understanding the origin and functions of the topographic organisation of the primate visual system. Yet, vision is most commonly modelled by convolutional neural networks that ignore…

Neurons and Cognition · Quantitative Biology 2023-08-21 Zejin Lu , Adrien Doerig , Victoria Bosch , Bas Krahmer , Daniel Kaiser , Radoslaw M Cichy , Tim C Kietzmann

This paper investigates the foundations of deep learning through insight of geometry, algebra and differential calculus. At is core, artificial intelligence relies on assumption that data and its intrinsic structure can be embedded into…

Differential Geometry · Mathematics 2025-10-22 Tsemo Aristide

Biological neural networks exist in physical space where distance influences communication delays: a fundamental coupling between space and time absent in most artificial neural networks. While recent work has separately explored spatial…

Neural and Evolutionary Computing · Computer Science 2026-01-27 Balázs Mészáros , James C. Knight , Danyal Akarca , Thomas Nowotny

The human brain represents objects in a way that is both invariant across instances and flexible enough to support different contexts and tasks. Yet it remains unknown how object representations are dynamically remapped as the same object…

Neurons and Cognition · Quantitative Biology 2026-05-27 Julien Dirani , Shankar Chawla , Leila Wehbe , Bradford Z. Mahon

Geometric trees are characterized by their tree-structured layout and spatially constrained nodes and edges, which significantly impacts their topological attributes. This inherent hierarchical structure plays a crucial role in domains such…

Machine Learning · Computer Science 2024-08-19 Zheng Zhang , Allen Zhang , Ruth Nelson , Giorgio Ascoli , Liang Zhao

We introduce and study methods for inferring and learning from correspondences among neurons. The approach enables alignment of data from distinct multiunit studies of nervous systems. We show that the methods for inferring correspondences…

Neurons and Cognition · Quantitative Biology 2015-01-28 Ashish Kapoor , E. Paxon Frady , Stefanie Jegelka , William B. Kristan , Eric Horvitz

Can neural networks learn goal-directed behaviour using similar strategies to the brain, by combining the relationships between the current state of the organism and the consequences of future actions? Recent work has shown that recurrent…

Neurons and Cognition · Quantitative Biology 2021-01-21 Justin Jude , Matthias H. Hennig

The hippocampal-entorhinal complex plays a major role in the organization of memory and thought. The formation of and navigation in cognitive maps of arbitrary mental spaces via place and grid cells can serve as a representation of memories…

Neurons and Cognition · Quantitative Biology 2022-10-31 Paul Stoewer , Achim Schilling , Andreas Maier , Patrick Krauss

Spatial awareness in mammals is based on an internalized representation of the environment, encoded by large networks of spiking neurons. While such representations can last for a long time, the underlying neuronal network is transient:…

Neurons and Cognition · Quantitative Biology 2016-02-03 Andrey Babichev , Yuri Dabaghian

Tracking the positions of objects in local space is a core function of animal brains. We do not yet understand how it is done with limited neural resources. The challenges of spatial cognition are discussed under the criteria: (a) scaling…

Neurons and Cognition · Quantitative Biology 2020-11-20 Robert Worden

Inspired by animal navigation strategies, we introduce a novel computational model to navigate and map a space rooted in biologically inspired principles. Animals exhibit extraordinary navigation prowess, harnessing memory, imagination, and…

Robotics · Computer Science 2025-01-07 Daria de Tinguy , Tim Verbelen , Bart Dhoedt

Recent numerical experiments have demonstrated that the choice of optimization geometry used during training can impact generalization performance when learning expressive nonlinear model classes such as deep neural networks. These…

Machine Learning · Computer Science 2022-04-25 Nicholas M. Boffi , Stephen Tu , Jean-Jacques E. Slotine

Grid cells in the entorhinal cortex encode the position of an animal in its environment using spatially periodic tuning curves of varying periodicity. Recent experiments established that these cells are functionally organized in discrete…

Neurons and Cognition · Quantitative Biology 2016-01-13 Noga Weiss Mosheiff , Haggai Agmon , Avraham Moriel , Yoram Burak

To navigate a space, the brain makes an internal representation of the environment using different cells such as place cells, grid cells, head direction cells, border cells, and speed cells. All these cells, along with sensory inputs,…

Robotics · Computer Science 2026-04-17 Hibatallah Meliani , Khadija Slimani , Samira Khoulji

Advances in experimental neuroscience have transformed our ability to explore the structure and function of neural circuits. At the same time, advances in machine learning have unleashed the remarkable computational power of artificial…

Neurons and Cognition · Quantitative Biology 2021-11-23 SueYeon Chung , L. F. Abbott

Much of the genome is expressed in the vertebrate brain, with individual genes exhibiting different spatially-varying patterns of expression. These variations are not independent, with pairs of genes exhibiting complex patterns of…

Quantitative Methods · Quantitative Biology 2012-01-06 Pascal Grange , Jason Bohland , Hemant Bokil , Sacha Nelson , Benjamin Okaty , Ken Sugino , Lydia Ng , Michael Hawrylycz , Partha P. Mitra

Mammalian hippocampus plays a key role in spatial learning and memory, but the exact nature of the hippocampal representation of space is still being explored. Recently, there has been a fair amount of success in modeling hippocampal…

Neurons and Cognition · Quantitative Biology 2016-01-19 Kentaro Hoffman , Andrey Babichev , Yuri Dabaghian

Neurons in cortical areas often integrate signals from different origins. In the primary visual cortex (V1), neural responses are modulated by non-visual context such as the animal's position. However, the spatial profile of these position…

Neurons and Cognition · Quantitative Biology 2025-12-02 Mai M. Morimoto , Julien Fournier , Aman B. Saleem

We describe coordinate systems adapted for the space between two surfaces, such as those delineating the highly folded cortex in mammalian brains. These systems are estimated in order to satisfy geometric priors, including streamline…

Optimization and Control · Mathematics 2019-11-20 Laurent Younes , Kwame S. Kutten , J. Tilak Ratnanather