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In this work, we develop an adaptive, multivariate partitioning algorithm for solving mixed-integer nonlinear programs (MINLP) with multi-linear terms to global optimality. This iterative algorithm primarily exploits the advantages of…
Given an irregular dense tensor, how can we efficiently analyze it? An irregular tensor is a collection of matrices whose columns have the same size and rows have different sizes from each other. PARAFAC2 decomposition is a fundamental tool…
We present a parallel algorithm and scalable implementation for genome analysis, specifically the problem of finding overlaps and alignments for data from "third generation" long read sequencers. While long sequences of DNA offer enormous…
Our Microbiome Network Alignment Algorithm (MiNAA) aligns two microbial networks using a combination of the GRAph ALigner (GRAAL) algorithm and the Hungarian algorithm. Network alignment algorithms find pairs of nodes (one node from the…
For over ten years, the constraint integer programming framework SCIP has been extended by capabilities for the solution of convex and nonconvex mixed-integer nonlinear programs (MINLPs). With the recently published version 8.0, these…
In-memory computing (IMC) with non-volatile memories (NVMs) has emerged as a promising approach to address the rapidly growing computational demands of Deep Neural Networks (DNNs). Mapping DNN layers spatially onto NVM-based IMC…
Rapid development of modern sequencing platforms enabled an unprecedented growth of protein families databases. The abundance of sets composed of hundreds of thousands sequences is a great challenge for multiple sequence alignment…
We investigate the compression of deep neural networks by quantizing their weights and activations into multiple binary bases, known as multi-bit networks (MBNs), which accelerate the inference and reduce the storage for the deployment on…
The quality of finetuning data is crucial for aligning large language models (LLMs) with human values. Current methods to improve data quality are either labor-intensive or prone to factual errors caused by LLM hallucinations. This paper…
We propose an adaptive fine-tuning algorithm for multimodal large models. The core steps of this algorithm involve two stages of truncation. First, the vast amount of data is projected into a semantic vector space, and the MiniBatchKMeans…
A standard approach to solving optimistic bilevel linear programs (BLPs) is to replace the lower-level problem with its Karush-Kuhn-Tucker (KKT) optimality conditions and reformulate the resulting complementarity constraints using auxiliary…
We describe novel subgradient methods for a broad class of matrix optimization problems involving nuclear norm regularization. Unlike existing approaches, our method executes very cheap iterations by combining low-rank stochastic…
Deep learning-based object detectors have achieved impressive performance in microscopy imaging, yet their confidence estimates often lack calibration, limiting their reliability for biomedical applications. In this work, we introduce a new…
We introduce milearn, a Python package for multi-instance learning (MIL) that follows the familiar scikit-learn fit/predict interface while providing a unified framework for both classical and neural-network-based MIL algorithms for…
The AmpRed package has been updated with an improved method for analytic continuation of complex integrals. Compared to the previous version, the new implementation significantly enhances computational efficiency for evaluating complex…
Nearest neighbor (NN) algorithms have been extensively used for missing data problems in recommender systems and sequential decision-making systems. Prior theoretical analysis has established favorable guarantees for NN when the underlying…
We aim at segmenting small organs (e.g., the pancreas) from abdominal CT scans. As the target often occupies a relatively small region in the input image, deep neural networks can be easily confused by the complex and variable background.…
Aims: We present a new upgraded version of ARES. The new version includes a series of interesting new features such as automatic radial velocity correction, a fully automatic continuum determination, and an estimation of the errors for the…
Linear solvers for large and sparse systems are a key element of scientific applications, and their efficient implementation is necessary to harness the computational power of current computers. Algebraic MultiGrid (AMG) preconditioners are…
The GooFit package provides physicists a simple, familiar syntax for manipulating probability density functions and performing fits, and is highly optimized for data analysis on NVIDIA GPUs and multithreaded CPU backends. GooFit was updated…