English
Related papers

Related papers: A k-mer Based Approach for SARS-CoV-2 Variant Iden…

200 papers

Pattern detection and string matching are fundamental problems in computer science and the accelerated expansion of bioinformatics and computational biology have made them a core topic for both disciplines. The SARS-CoV-2 pandemic has made…

Genomics · Quantitative Biology 2025-05-14 Konstantinos Xylogiannopoulos

Covid-19 infection, which spread to the whole world in December 2019 and is still active, caused more than 250 thousand deaths in the world today. Researches on this subject have been focused on analyzing the genetic structure of the virus,…

Machine Learning · Computer Science 2023-04-25 Selcuk Yazar

The COVID-19 pandemic is spreading rapidly around the world, causing countries to impose lockdowns and efforts to develop vaccines on a global scale. However, human-to-animal and animal-to-human transmission cannot be ignored, as severe…

Populations and Evolution · Quantitative Biology 2024-08-20 Zi Hian Tan , Kian Yan Yong , Jian-Jun Shu

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a worldwide devastating effect. The understanding of evolution and transmission of SARS-CoV-2 is of paramount importance for the…

Quantitative Methods · Quantitative Biology 2021-01-01 Yuta Hozumi , Rui Wang , Changchuan Yin , Guo-Wei Wei

The rapid evolution and global impact of coronaviruses, notably SARS-CoV-1 and SARS-CoV-2, underscore the importance of understanding their molecular mechanisms in detail. This study focuses on the receptor-binding motif (RBM) within the…

Biological Physics · Physics 2026-03-16 Rafael B. Frigori

Emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have compromised existing vaccines and posed a grand challenge to coronavirus disease 2019 (COVID-19) prevention, control, and global economic recovery. For…

Biomolecules · Quantitative Biology 2022-04-21 Jiahui Chen , Guo-Wei Wei

Genomic surveillance of infectious diseases allows monitoring circulating and emerging variants and quantifying their epidemic potential. However, due to the high costs associated with genomic sequencing, only a limited number of samples…

In this worldwide spread of SARS-CoV-2 (COVID-19) infection, it is of utmost importance to detect the disease at an early stage especially in the hot spots of this epidemic. There are more than 110 Million infected cases on the globe,…

Image and Video Processing · Electrical Eng. & Systems 2021-02-23 Sohail Iqbal , H. Fareed Ahmed , Talha Qaiser , Muhammad Imran Qureshi , Nasir Rajpoot

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has emphasized the importance and challenges of correctly interpreting antibody test results. Identification of positive and negative samples requires a…

Quantitative Methods · Quantitative Biology 2023-04-26 Rayanne A. Luke , Anthony J. Kearsley , Nora Pisanic , Yukari C. Manabe , David L. Thomas , Christopher D. Heaney , Paul N. Patrone

The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has spurred unprecedented and concerted worldwide research to curtail and eradicate this pathogen. SARS-CoV-2 has four structural proteins:…

Biological Physics · Physics 2022-09-26 Siyu Li , Roya Zandi

In the past several months, COVID-19 has spread over the globe and caused severe damage to the people and the society. In the context of this severe situation, an effective drug discovery method to generate potential drugs is extremely…

Machine Learning · Computer Science 2021-04-26 Tianyue Cheng , Tianchi Fan , Landi Wang

Through the use of cutting-edge unsupervised classification techniques from statistics and machine learning, we characterise symptom phenotypes among symptomatic SARS-CoV-2 PCR-positive community cases. We first analyse each dataset in…

The large-scale evolution of the SARS-CoV-2 virus has been marked by rapid turnover of genetic clades. New variants show intrinsic changes, notably increased transmissibility, as well as antigenic changes that reduce the cross-immunity…

Populations and Evolution · Quantitative Biology 2022-07-20 Matthijs Meijers , Denis Ruchnewitz , Marta Łuksza , Michael Lässig

The clinical spectrum of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the strain of coronavirus that caused the COVID-19 pandemic, is broad, extending from asymptomatic infection to severe immunopulmonary reactions that, if…

Quantitative Methods · Quantitative Biology 2022-07-18 Aaron Wang , Feng Li , Samantha Chiang , Jennifer Fulcher , Otto Yang , David Wong , Fang Wei

The devastating impact of the COVID-19 pandemic caused by SARS coronavirus 2 (SARS CoV 2) has raised important questions about viral origin, mechanisms of zoonotic transfer to humans, whether companion or commercial animals can act as…

Biomolecules · Quantitative Biology 2021-07-12 Sakshi Piplani , Puneet Kumar Singh , David A. Winkler , Nikolai Petrovsky

Although previous infection and vaccination provide protection against SARS-CoV-2 infection, both reinfection and breakthrough infection are possible events whose occurrence would increase with time after first exposure to the antigen and…

Populations and Evolution · Quantitative Biology 2022-06-07 Ariel Félix Gualtieri , Carolina de la Cal , Augusto Francisco Toma , Pedro Hecht

The importance of understanding SARS-CoV-2 evolution cannot be overemphasized. Recent studies confirm that natural selection is the dominating mechanism of SARS-CoV-2 evolution, which favors mutations that strengthen viral infectivity. We…

Populations and Evolution · Quantitative Biology 2021-10-12 Rui Wang , Jiahui Chen , Guo-Wei Wei

CovID-19 genetics analysis is critical to determine virus type,virus variant and evaluate vaccines. In this paper, SARS-Cov-2 RNA sequence analysis relative to region or territory is investigated. A uniform framework of sequence SVM model…

Quantitative Methods · Quantitative Biology 2021-01-12 Jingwei Liu

The recent global surge in COVID-19 infections has been fueled by new SARS-CoV-2 variants, namely Alpha, Beta, Gamma, Delta, etc. The molecular mechanism underlying such surge is elusive due to 4,653 non-degenerate mutations on the spike…

Biomolecules · Quantitative Biology 2021-09-13 Rui Wang , Jiahui Chen , Yuta Hozumi , Changchuan Yin , Guo-Wei Wei