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The use of machine learning (ML) techniques in the biomedical field has become increasingly important, particularly with the large amounts of data generated by the aftermath of the COVID-19 pandemic. However, due to the complex nature of…

Machine Learning · Computer Science 2023-03-17 Anthony Onoja , Francesco Raimondi

In clinical practice, decision-making relies heavily on established protocols, often formalised as rules. Concurrently, Machine Learning (ML) models, trained on clinical data, aspire to integrate into medical decision-making processes.…

Artificial Intelligence · Computer Science 2024-11-06 Christel Sirocchi , Muhammad Suffian , Federico Sabbatini , Alessandro Bogliolo , Sara Montagna

Vision-language foundation models achieve promising performance in natural image classification, yet their direct application to medical imaging is limited by severe domain shifts, resolution mismatches, and the multi-label nature of…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Yitong Li , Morteza Ghahremani , Christian Wachinger

In spite of the strong performance of machine learning (ML) models in radiology, they have not been widely accepted by radiologists, limiting clinical integration. A key reason is the lack of explainability, which ensures that model…

Human-Computer Interaction · Computer Science 2026-04-14 Sara Ketabi , Matthias W. Wagner , Birgit Betina Ertl-Wagner , Greg A. Jamieson , Farzad Khalvati

The increasing availability of large collections of electronic health record (EHR) data and unprecedented technical advances in deep learning (DL) have sparked a surge of research interest in developing DL based clinical decision support…

Machine Learning · Computer Science 2021-12-07 Di Jin , Elena Sergeeva , Wei-Hung Weng , Geeticka Chauhan , Peter Szolovits

With the advent of sophisticated machine learning (ML) techniques and the promising results they yield, especially in medical applications, where they have been investigated for different tasks to enhance the decision-making process. Since…

Translating machine learning (ML) models effectively to clinical practice requires establishing clinicians' trust. Explainability, or the ability of an ML model to justify its outcomes and assist clinicians in rationalizing the model…

Machine Learning · Computer Science 2019-08-08 Sana Tonekaboni , Shalmali Joshi , Melissa D McCradden , Anna Goldenberg

The lack of transparency and explainability hinders the clinical adoption of Machine learning (ML) algorithms. While explainable artificial intelligence (XAI) methods have been proposed, little research has focused on the agreement between…

Machine Learning · Computer Science 2023-11-29 Aida Brankovic , Wenjie Huang , David Cook , Sankalp Khanna , Konstanty Bialkowski

Machine Learning (ML) has recently been demonstrated to rival expert-level human accuracy in prediction and detection tasks in a variety of domains, including medicine. Despite these impressive findings, however, a key barrier to the full…

Artificial Intelligence · Computer Science 2021-07-01 D. Fompeyrine , E. S. Vorm , N. Ricka , F. Rose , G. Pellegrin

Although explainability is essential in the clinical diagnosis, most deep learning models still function as black boxes without elucidating their decision-making process. In this study, we investigate the explainable model development that…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Yunhe Gao , Difei Gu , Mu Zhou , Dimitris Metaxas

There is a growing demand for the use of Artificial Intelligence (AI) and Machine Learning (ML) in healthcare, particularly as clinical decision support systems to assist medical professionals. However, the complexity of many of these…

Human-Computer Interaction · Computer Science 2025-05-13 Dima Alattal , Asal Khoshravan Azar , Puja Myles , Richard Branson , Hatim Abdulhussein , Allan Tucker

Machine learning (ML) approaches have demonstrated promising results in a wide range of healthcare applications. Data plays a crucial role in developing ML-based healthcare systems that directly affect people's lives. Many of the ethical…

Recent engineering developments in specialised computational hardware, data-acquisition and storage technology have seen the emergence of Machine Learning (ML) as a powerful form of data analysis with widespread applicability beyond its…

Machine Learning · Computer Science 2022-05-19 Ashwin Srinivasan , Michael Bain , Enrico Coiera

Recent efforts in Machine Learning (ML) interpretability have focused on creating methods for explaining black-box ML models. However, these methods rely on the assumption that simple approximations, such as linear models or decision-trees,…

Machine Learning · Computer Science 2019-06-13 Owen Lahav , Nicholas Mastronarde , Mihaela van der Schaar

Increasing number of sectors which affect human lives, are using Machine Learning (ML) tools. Hence the need for understanding their working mechanism and evaluating their fairness in decision-making, are becoming paramount, ushering in the…

Machine Learning · Computer Science 2020-05-11 Sreejita Ghosh , Peter Tino , Kerstin Bunte

Time-series learning is the bread and butter of data-driven *clinical decision support*, and the recent explosion in ML research has demonstrated great potential in various healthcare settings. At the same time, medical time-series problems…

Machine Learning · Computer Science 2023-10-31 Daniel Jarrett , Jinsung Yoon , Ioana Bica , Zhaozhi Qian , Ari Ercole , Mihaela van der Schaar

Concept Bottleneck Models (CBMs) are a prominent framework for interpretable AI that map learned visual features to a set of meaningful concepts for task-specific downstream predictions. Their sequential structure enhances transparency by…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Mohamed Harmanani , Bining Long , Zhuoxin Guo , Paul F. R. Wilson , Amirhossein Sabour , Minh Nguyen Nhat To , Gabor Fichtinger , Purang Abolmaesumi , Parvin Mousavi

The global need for effective disease diagnosis remains substantial, given the complexities of various disease mechanisms and diverse patient symptoms. To tackle these challenges, researchers, physicians, and patients are turning to machine…

Machine Learning · Computer Science 2023-10-27 S M Atikur Rahman , Sifat Ibtisum , Ehsan Bazgir , Tumpa Barai

Medical vision-and-language models (MVLMs) have attracted substantial interest due to their capability to offer a natural language interface for interpreting complex medical data. Their applications are versatile and have the potential to…

Computer Vision and Pattern Recognition · Computer Science 2024-11-20 Qi Chen , Ruoshan Zhao , Sinuo Wang , Vu Minh Hieu Phan , Anton van den Hengel , Johan Verjans , Zhibin Liao , Minh-Son To , Yong Xia , Jian Chen , Yutong Xie , Qi Wu

Large language models (LLMs) hold great promise for medical applications and are evolving rapidly, with new models being released at an accelerated pace. However, benchmarking on large-scale real-world data such as electronic health records…

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