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CellProfiler is a widely used software for creating reproducible, reusable image analysis workflows without needing to code. In addition to the >90 modules that make up the main CellProfiler program, CellProfiler has a plugins system that…

Biological image analysis has traditionally focused on measuring specific visual properties of interest for cells or other entities. A complementary paradigm gaining increasing traction is image-based profiling - quantifying many distinct…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Alán F. Muñoz , Tim Treis , Alexandr A. Kalinin , Shatavisha Dasgupta , Fabian Theis , Anne E. Carpenter , Shantanu Singh

Cellular image segmentation is essential for quantitative biology yet remains difficult due to heterogeneous modalities, morphological variability, and limited annotations. We present GenCellAgent, a training-free multi-agent framework that…

Quantitative Methods · Quantitative Biology 2026-05-12 Xi Yu , Yang Yang , Qun Liu , Yonghua Du , Sean McSweeney , Yuewei Lin

Increasing data set sizes of 3D microscopy imaging experiments demand for an automation of segmentation processes to be able to extract meaningful biomedical information. Due to the shortage of annotated 3D image data that can be used for…

Image and Video Processing · Electrical Eng. & Systems 2022-02-02 Dennis Eschweiler , Richard S. Smith , Johannes Stegmaier

Here we report on a set of programs developed at the ZMBH Bio-Imaging Facility for tracking real-life images of cellular processes. These programs perform 1) automated tracking; 2) quantitative and comparative track analyses of different…

Biological Physics · Physics 2017-03-09 Aliakbar Jafarpour , Holger Lorenz

Datasets (semi-)automatically collected from the web can easily scale to millions of entries, but a dataset's usefulness is directly related to how clean and high-quality its examples are. In this paper, we describe and publicly release an…

Computer Vision and Pattern Recognition · Computer Science 2020-08-24 Houda Alberts , Iacer Calixto

Methods: We have developed a software suite (DataSet Tracker) for real-time analysis designed to run on computers, smartphones, and smart glasses hardware and suitable for resource-constrained, on-the-fly computing in microscopes without…

Quantitative Methods · Quantitative Biology 2025-08-13 Alexandre Matov

Photo Rater is a computer vision project that uses neural networks to help photographers select the best photo among those that are taken based on the same scene. This process is usually referred to as "culling" in photography, and it can…

Computer Vision and Pattern Recognition · Computer Science 2023-10-18 Wentao Guo , Charlie Ruan , Claire Zhou

Profiling data by plotting distributions and analyzing summary statistics is a critical step throughout data analysis. Currently, this process is manual and tedious since analysts must write extra code to examine their data after every…

Human-Computer Interaction · Computer Science 2023-08-09 Will Epperson , Vaishnavi Gorantla , Dominik Moritz , Adam Perer

Currently, food image recognition tasks are evaluated against fixed datasets. However, in real-world conditions, there are cases in which the number of samples in each class continues to increase and samples from novel classes appear. In…

Computer Vision and Pattern Recognition · Computer Science 2022-12-23 Shota Horiguchi , Sosuke Amano , Makoto Ogawa , Kiyoharu Aizawa

Providing high-quality electron images and hyperspectral X-ray maps is a focus of many modern electron microscopy laboratories. Nevertheless, further image processing and annotations are often needed to prepare them for publications and…

Image and Video Processing · Electrical Eng. & Systems 2021-03-24 Noah Kraft , Anette von der Handt

A wide range of scientific imaging datasets benefit from human inspection for purposes ranging from prosaic-such as fault identification and quality inspection-to profound, enabling the discovery of new phenomena. As such, these datasets…

Instrumentation and Methods for Astrophysics · Physics 2025-07-04 Ryan Walker , Andi Kisare , Lindsey Bleem

Image-based or morphological profiling is a rapidly expanding field wherein cells are "profiled" by extracting hundreds to thousands of unbiased, quantitative features from images of cells that have been perturbed by genetic or chemical…

Quantitative Methods · Quantitative Biology 2024-11-07 Erin Weisbart , Ankur Kumar , John Arevalo , Anne E. Carpenter , Beth A. Cimini , Shantanu Singh

ConsumerCheck is an open source data analysis software tailored for analysis of sensory and consumer data. Since some of the implemented methods are generic, such as PCA, PLSR and PCR, other data from other domains may also be analysed with…

Human-Computer Interaction · Computer Science 2022-01-12 Oliver Tomic , Alexandra Kuznetsova , Per Bruun Brockhoff , Thomas Graff , Tormod Næs

Advanced image segmentation and processing tools present an opportunity to study cell processes and their dynamics. However, image analysis is often routine and time-consuming. Nowadays, alternative data-driven approaches using deep…

We introduce CellSegmenter, a structured deep generative model and an amortized inference framework for unsupervised representation learning and instance segmentation tasks. The proposed inference algorithm is convolutional and…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 Luca D'Alessio , Mehrtash Babadi

Feature selection is used in machine learning to improve predictions, decrease computation time, reduce noise, and tune models based on limited sample data. In this article, we present FeatureExplorer, a visual analytics system that…

Human-Computer Interaction · Computer Science 2023-10-05 Jieqiong Zhao , Morteza Karimzadeh , Ali Masjedi , Taojun Wang , Xiwen Zhang , Melba M. Crawford , David S. Ebert

For over two decades, image-based profiling has revolutionized cell phenotype analysis. Image-based profiling processes rich, high-throughput, microscopy data into thousands of unbiased measurements that reveal phenotypic patterns powerful…

In the field of image-based drug discovery, capturing the phenotypic response of cells to various drug treatments and perturbations is a crucial step. However, existing methods require computationally extensive and complex multi-step…

Machine Learning · Computer Science 2025-02-28 Bo Li , Bob Zhang , Chengyang Zhang , Minghao Zhou , Weiliang Huang , Shihang Wang , Qing Wang , Mengran Li , Yong Zhang , Qianqian Song

This article demonstrates a new conceptor network based classifier in classifying images. Mathematical descriptions and analysis are presented. Various tests are experimented using three benchmark datasets: MNIST, CIFAR-10 and CIFAR-100.…

Computer Vision and Pattern Recognition · Computer Science 2015-06-15 Yuhuang Hu , M. S. Ishwarya , Chu Kiong Loo
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