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Related papers: Volumetric dose extension for isodose tuning

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Predictive dosimetry is central to enabling personalized radiopharmaceutical therapy (RPT), particularly in prostate specific membrane antigen (PSMA) targeted theranostics. In this work, we develop a three layer computational framework that…

Medical Physics · Physics 2026-02-02 Hamid Abdollahi , James Fowler , Carlos Uribe , Arman Rahmim

Objective: Clinical implementation of deformable image registration (DIR) requires voxel-based spatial accuracy metrics such as manually identified landmarks, which are challenging to implement for highly mobile gastrointestinal (GI)…

We propose a fast beam orientation selection method, based on deep neural networks (DNN), capable of developing a plan comparable to those by the state-of-the-art column generation method. The novelty of Our model lies in its supervised…

Medical Physics · Physics 2019-12-23 Azar Sadeghnejad Barkousaraie , Olalekan Ogunmolu , Steve Jiang , Dan Nguyen

Aim: To improve treatment plan robustness with respect to small shifts in patient position during the VMAT treatment by ensuring a linear ramp-like dose profile in treatment field overlap regions. Background: Craniospinal irradiation (CSI)…

Medical Physics · Physics 2016-03-30 Andrej Strojnik , Ignasi Mendez , Primoz Peterlin

Purpose: This is a theoretical simulation study for proof of concept of radiochromic film dosimetry to measure physical and biological doses without plan-based quenching correction for patient-specific quality assurance of carbon-ion…

Medical Physics · Physics 2019-03-25 Nobuyuki Kanematsu , Taku Inaniwa , Shunsuke Yonai , Hideyuki Mizuno

Stereotactic body radiation therapy allows for a precise and accurate dose delivery. Organ motion during treatment bears the risk of undetected high dose healthy tissue exposure. An organ very susceptible to high dose is the oesophagus. Its…

Medical Physics · Physics 2021-06-22 Tobias Fechter , Sonja Adebahr , Anca-Ligia Grosu , Dimos Baltas

Purpose: We aims to examine the impact of different head tilt angles on the dose distribution in the whole-brain target area and organs at risk. It also aims to determine the head tilt angle to achieve optimal radiation therapy outcomes.…

Medical Physics · Physics 2024-06-03 Cuiyun Yuan , Sisi Xu , Yang Li , Enzhuo Quan , Dongjie Chen , Jun Liang , Chenbin Liu

Today, intensity-modulated radiation therapy (IMRT) is one of the methods used to treat brain tumors. In conventional treatment planning methods, after identifying planning target volume (PTV), and organs at risk (OARs), and determining the…

Quantitative Methods · Quantitative Biology 2023-05-15 Mobina Naeemi , Mohamad Reza Esmaeili , Iraj Abedi

$Objective$. Obtaining the intrinsic dose distributions in particle therapy is a challenging problem that needs to be addressed by imaging algorithms to take advantage of secondary particle detectors. In this work, we investigate the…

Instrumentation and Detectors · Physics 2022-09-28 Atiq. Ur. Rahman , Mythra Varun. Nemallapudi , Cheng-Ying. Chou , Shih-Chang Lee , Chih-Hsun. Lin

Text-conditioned generative models for volumetric medical imaging provide semantic control but lack explicit anatomical guidance, often resulting in outputs that are spatially ambiguous or anatomically inconsistent. In contrast,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Daniele Molino , Camillo Maria Caruso , Paolo Soda , Valerio Guarrasi

Accurate dose calculation is vitally important for proton therapy. Pencil beam (PB) model-based dose calculation is fast but inaccurate due to the approximation when dealing with inhomogeneities. Monte Carlo (MC) dose calculation is the…

Techniques for preclinical intensity modulated radiation therapy are being developed to improve translation by replicating the clinical paradigm. This study presents the first treatment planning comparison between small animal IMRT…

The interplay between the beam delivery time structure and the patient motion makes 4D dose calculation (4DDC) important when treating moving tumors with intensity modulated proton therapy. 4DDC based on phase sorting of a 4DCT suffers from…

Medical Physics · Physics 2023-10-13 Ivar Bengtsson , Erik Engwall , Albin Fredriksson , Lars Glimelius

Digital Breast Tomosynthesis is an X-ray imaging technique that allows a volumetric reconstruction of the breast, from a small number of low-dose two-dimensional projections. Although it is already used in clinical setting, enhancing the…

Numerical Analysis · Mathematics 2020-07-21 Elena Morotti , Elena Loli Piccolomini

Mandibular reconstruction with vascularized bone grafts is complicated by donor-host nonunion, and current virtual surgical planning produces a geometric plan rather than a configuration that explicitly promotes bone union. We present…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Hamidreza Aftabi , John E. Lloyd , Amanda Ding , Benedikt Sagl , Eitan Prisman , Antony Hodgson , Sidney Fels

A standard dose of radioactive tracer must be delivered into the patients body to obtain high-quality Positron Emission Tomography (PET) images for diagnostic purposes, which raises the risk of radiation harm. A reduced tracer dose, on the…

In recent years, volumetric modulated arc therapy (VMAT) has been becoming a more and more important radiation technique widely used in clinical application for cancer treatment. One of the key problems in VMAT is treatment plan…

Medical Physics · Physics 2016-01-06 Yu Yang , Bin Dong , Zaiwen Wen

Low-dose computed tomography (LDCT) reduces patient radiation exposure but introduces substantial noise that degrades image quality and hinders diagnostic accuracy. Existing denoising approaches often require many diffusion steps, limiting…

Medical Physics · Physics 2025-10-29 Qiang Li , Mojtaba Safari , Shansong Wang , Huiqiao Xie , Jie Ding , Tonghe Wang , Xiaofeng Yang

Purpose: To develop a knowledge-based voxel-wise dose prediction system using a convolution neural network for high-dose-rate brachytherapy cervical cancer treatments with a tandem-and-ovoid (T&O) applicator. Methods: A 3D U-NET was…

Ischemic strokes are often caused by large vessel occlusions (LVOs), which can be visualized and diagnosed with Computed Tomography Angiography scans. As time is brain, a fast, accurate and automated diagnosis of these scans is desirable.…

Image and Video Processing · Electrical Eng. & Systems 2022-05-17 Florian Thamm , Oliver Taubmann , Markus Jürgens , Aleksandra Thamm , Felix Denzinger , Leonhard Rist , Hendrik Ditt , Andreas Maier
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