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A recently-proposed technique called self-adaptive training augments modern neural networks by allowing them to adjust training labels on the fly, to avoid overfitting to samples that may be mislabeled or otherwise non-representative. By…

Machine Learning · Computer Science 2020-06-16 Daniel Chiu , Franklyn Wang , Scott Duke Kominers

Deep learning models face persistent challenges in training, particularly due to internal covariate shift and label shift. While single-mode normalization methods like Batch Normalization partially address these issues, they are constrained…

Machine Learning · Computer Science 2024-10-31 Bilal Faye , Hanane Azzag , Mustapha Lebbah , Djamel Bouchaffra

In machine learning, if the training data is an unbiased sample of an underlying distribution, then the learned classification function will make accurate predictions for new samples. However, if the training data is not an unbiased sample,…

Machine Learning · Computer Science 2019-01-15 Wouter M. Kouw , Marco Loog

This paper explores a multimodal co-training framework designed to enhance model generalization in situations where labeled data is limited and distribution shifts occur. We thoroughly examine the theoretical foundations of this framework,…

Machine Learning · Computer Science 2025-10-10 Tianyu Bell Pan , Damon L. Woodard

Learning with noisy labels aims to ensure model generalization given a label-corrupted training set. The sample selection strategy achieves promising performance by selecting a label-reliable subset for model training. In this paper, we…

Machine Learning · Computer Science 2025-04-11 Qi Wei , Lei Feng , Haobo Wang , Bo An

When a subgroup is identified from the data, it must be evaluated in a replicable way. The usual in-sample approach, which evaluates the post-hoc identified subgroup as predefined, might suffer from selection bias. This issue of in-sample…

Methodology · Statistics 2026-05-06 Shuoxun Xu , Xinzhou Guo

Whole-slide image (WSI) classification is a challenging task because 1) patches from WSI lack annotation, and 2) WSI possesses unnecessary variability, e.g., stain protocol. Recently, Multiple-Instance Learning (MIL) has made significant…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Joohyung Lee , Heejeong Nam , Kwanhyung Lee , Sangchul Hahn

With large volumes of health care data comes the research area of computational phenotyping, making use of techniques such as machine learning to describe illnesses and other clinical concepts from the data itself. The "traditional"…

Machine Learning · Statistics 2016-12-30 Chris Hodapp

Annotated images and ground truth for the diagnosis of rare and novel diseases are scarce. This is expected to prevail, considering the small number of affected patient population and limited clinical expertise to annotate images. Further,…

Computer Vision and Pattern Recognition · Computer Science 2022-11-01 Karthik Desingu , Mirunalini P. , Aravindan Chandrabose

Deep learning models usually suffer from domain shift issues, where models trained on one source domain do not generalize well to other unseen domains. In this work, we investigate the single-source domain generalization problem: training a…

Computer Vision and Pattern Recognition · Computer Science 2023-04-24 Cheng Ouyang , Chen Chen , Surui Li , Zeju Li , Chen Qin , Wenjia Bai , Daniel Rueckert

In many machine learning domains, datasets are characterized by highly imbalanced and overlapping classes. Particularly in the medical domain, a specific list of symptoms can be labeled as one of various different conditions. Some of these…

Machine Learning · Computer Science 2020-06-03 Ran Ilan Ber , Tom Haramaty

Important objectives in cancer research are the prediction of a patient's risk based on molecular measurements such as gene expression data and the identification of new prognostic biomarkers (e.g. genes). In clinical practice, this is…

Applications · Statistics 2020-04-17 Katrin Madjar , Manuela Zucknick , Katja Ickstadt , Jörg Rahnenführer

We propose self-adaptive training---a new training algorithm that dynamically corrects problematic training labels by model predictions without incurring extra computational cost---to improve generalization of deep learning for potentially…

Machine Learning · Computer Science 2020-10-01 Lang Huang , Chao Zhang , Hongyang Zhang

Class distribution plays an important role in learning deep classifiers. When the proportion of each class in the test set differs from the training set, the performance of classification nets usually degrades. Such a label distribution…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Wenao Ma , Cheng Chen , Shuang Zheng , Jing Qin , Huimao Zhang , Qi Dou

We consider the problem of inferring the values of an arbitrary set of variables (e.g., risk of diseases) given other observed variables (e.g., symptoms and diagnosed diseases) and high-dimensional signals (e.g., MRI images or EEG). This is…

Machine Learning · Statistics 2019-02-07 Hao Wang , Chengzhi Mao , Hao He , Mingmin Zhao , Tommi S. Jaakkola , Dina Katabi

Neuroimaging datasets keep growing in size to address increasingly complex medical questions. However, even the largest datasets today alone are too small for training complex machine learning models. A potential solution is to increase…

Machine Learning · Computer Science 2019-07-10 Christian Wachinger , Benjamin Gutierrez Becker , Anna Rieckmann , Sebastian Pölsterl

Shortcut learning undermines model generalization to out-of-distribution data. While the literature attributes shortcuts to biases in superficial features, we show that imbalances in the semantic distribution of sample embeddings induce…

Machine Learning · Computer Science 2025-06-24 Shuo Yang , Bardh Prenkaj , Gjergji Kasneci

We introduce a novel end-to-end approach for learning to cluster in the absence of labeled examples. Our clustering objective is based on optimizing normalized cuts, a criterion which measures both intra-cluster similarity as well as…

Machine Learning · Computer Science 2019-10-18 Azade Nazi , Will Hang , Anna Goldie , Sujith Ravi , Azalia Mirhoseini

New medical datasets are now more open to the public, allowing for better and more extensive research. Although prepared with the utmost care, new datasets might still be a source of spurious correlations that affect the learning process.…

Image and Video Processing · Electrical Eng. & Systems 2022-09-23 Agnieszka Mikołajczyk , Sylwia Majchrowska , Sandra Carrasco Limeros

The well known domain shift issue causes model performance to degrade when deployed to a new target domain with different statistics to training. Domain adaptation techniques alleviate this, but need some instances from the target domain to…

Machine Learning · Computer Science 2019-06-11 Yiying Li , Yongxin Yang , Wei Zhou , Timothy M. Hospedales