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A recently-proposed technique called self-adaptive training augments modern neural networks by allowing them to adjust training labels on the fly, to avoid overfitting to samples that may be mislabeled or otherwise non-representative. By…
Deep learning models face persistent challenges in training, particularly due to internal covariate shift and label shift. While single-mode normalization methods like Batch Normalization partially address these issues, they are constrained…
In machine learning, if the training data is an unbiased sample of an underlying distribution, then the learned classification function will make accurate predictions for new samples. However, if the training data is not an unbiased sample,…
This paper explores a multimodal co-training framework designed to enhance model generalization in situations where labeled data is limited and distribution shifts occur. We thoroughly examine the theoretical foundations of this framework,…
Learning with noisy labels aims to ensure model generalization given a label-corrupted training set. The sample selection strategy achieves promising performance by selecting a label-reliable subset for model training. In this paper, we…
When a subgroup is identified from the data, it must be evaluated in a replicable way. The usual in-sample approach, which evaluates the post-hoc identified subgroup as predefined, might suffer from selection bias. This issue of in-sample…
Whole-slide image (WSI) classification is a challenging task because 1) patches from WSI lack annotation, and 2) WSI possesses unnecessary variability, e.g., stain protocol. Recently, Multiple-Instance Learning (MIL) has made significant…
With large volumes of health care data comes the research area of computational phenotyping, making use of techniques such as machine learning to describe illnesses and other clinical concepts from the data itself. The "traditional"…
Annotated images and ground truth for the diagnosis of rare and novel diseases are scarce. This is expected to prevail, considering the small number of affected patient population and limited clinical expertise to annotate images. Further,…
Deep learning models usually suffer from domain shift issues, where models trained on one source domain do not generalize well to other unseen domains. In this work, we investigate the single-source domain generalization problem: training a…
In many machine learning domains, datasets are characterized by highly imbalanced and overlapping classes. Particularly in the medical domain, a specific list of symptoms can be labeled as one of various different conditions. Some of these…
Important objectives in cancer research are the prediction of a patient's risk based on molecular measurements such as gene expression data and the identification of new prognostic biomarkers (e.g. genes). In clinical practice, this is…
We propose self-adaptive training---a new training algorithm that dynamically corrects problematic training labels by model predictions without incurring extra computational cost---to improve generalization of deep learning for potentially…
Class distribution plays an important role in learning deep classifiers. When the proportion of each class in the test set differs from the training set, the performance of classification nets usually degrades. Such a label distribution…
We consider the problem of inferring the values of an arbitrary set of variables (e.g., risk of diseases) given other observed variables (e.g., symptoms and diagnosed diseases) and high-dimensional signals (e.g., MRI images or EEG). This is…
Neuroimaging datasets keep growing in size to address increasingly complex medical questions. However, even the largest datasets today alone are too small for training complex machine learning models. A potential solution is to increase…
Shortcut learning undermines model generalization to out-of-distribution data. While the literature attributes shortcuts to biases in superficial features, we show that imbalances in the semantic distribution of sample embeddings induce…
We introduce a novel end-to-end approach for learning to cluster in the absence of labeled examples. Our clustering objective is based on optimizing normalized cuts, a criterion which measures both intra-cluster similarity as well as…
New medical datasets are now more open to the public, allowing for better and more extensive research. Although prepared with the utmost care, new datasets might still be a source of spurious correlations that affect the learning process.…
The well known domain shift issue causes model performance to degrade when deployed to a new target domain with different statistics to training. Domain adaptation techniques alleviate this, but need some instances from the target domain to…