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In many practical applications of machine learning, a discrepancy often arises between a source distribution from which labeled training examples are drawn and a target distribution for which only unlabeled data is observed. Traditionally,…

Machine Learning · Statistics 2025-03-05 Paweł Teisseyre , Jan Mielniczuk

Machine learning has a recognised need for large amounts of annotated data. Due to the high cost of expert annotations, crowdsourcing, where non-experts are asked to label or outline images, has been proposed as an alternative. Although…

Human-Computer Interaction · Computer Science 2020-07-08 Ralf Raumanns , Elif K Contar , Gerard Schouten , Veronika Cheplygina

Automating Multiple Sclerosis (MS) lesion segmentation would be of great benefit in initial diagnosis as well as monitoring disease progression. Deep learning based segmentation models perform well in many domains, but the state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Liviu Badea , Maria Popa

In whole slide images (WSIs) analysis, attention-based multi-instance learning (MIL) models are susceptible to spurious correlations and degrade under domain shift. These methods may assign high attention weights to non-tumor regions, such…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Xin Liu , Weijia Zhang , Wei Tang , Thuc Duy Le , Jiuyong Li , Lin Liu , Min-Ling Zhang

We propose a simple but effective multi-source domain generalization technique based on deep neural networks by incorporating optimized normalization layers that are specific to individual domains. Our approach employs multiple…

Machine Learning · Computer Science 2020-07-22 Seonguk Seo , Yumin Suh , Dongwan Kim , Geeho Kim , Jongwoo Han , Bohyung Han

Unsupervised models can provide supplementary soft constraints to help classify new, "target" data since similar instances in the target set are more likely to share the same class label. Such models can also help detect possible…

Machine Learning · Computer Science 2012-06-06 Ayan Acharya , Eduardo R. Hruschka , Joydeep Ghosh , Sreangsu Acharyya

Exploration of bias has significant impact on the transparency and applicability of deep learning pipelines in medical settings, yet is so far woefully understudied. In this paper, we consider two separate groups for which training data is…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Leonie Henschel , David Kügler , Derek S Andrews , Christine W Nordahl , Martin Reuter

Accurately measuring the evolution of Multiple Sclerosis (MS) with magnetic resonance imaging (MRI) critically informs understanding of disease progression and helps to direct therapeutic strategy. Deep learning models have shown promise…

Training large-scale recommendation models under a single global objective implicitly assumes homogeneity across user populations. However, real-world data are composites of heterogeneous cohorts with distinct conditional distributions. As…

Recently, there has been great progress in the ability of artificial intelligence (AI) algorithms to classify dermatological conditions from clinical photographs. However, little is known about the robustness of these algorithms in…

Background: Survival prediction models are often less reliable in clinical groups with limited sample sizes or few outcome events. Target-only models may be unstable, whereas models from larger cohorts may transfer poorly when risk-factor…

Methodology · Statistics 2026-05-18 Junhan Yu , Yurui Chen , Juan Delgado-SanMartin , Dennis Wang , Hong Pan , Doudou Zhou

Semi-supervised multi-label feature selection has recently been developed to solve the curse of dimensionality problem in high-dimensional multi-label data with certain samples missing labels. Although many efforts have been made, most…

Machine Learning · Computer Science 2025-10-10 Li Yang , Yanyong Huang , Dongjie Wang , Ke Li , Xiuwen Yi , Fengmao Lv , Tianrui Li

Deep learning could be prone to learning shortcuts raised by dataset bias and result in inaccurate, unreliable, and unfair models, which impedes its adoption in real-world clinical applications. Despite its significance, there is a dearth…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Luyang Luo , Xin Huang , Minghao Wang , Zhuoyue Wan , Hao Chen

When evaluating the performance of clinical machine learning models, one must consider the deployment population. When the population of patients with observed labels is only a subset of the deployment population (label selection), standard…

Machine Learning · Computer Science 2022-09-20 Conor K. Corbin , Michael Baiocchi , Jonathan H. Chen

Medical multimodal representation learning aims to integrate heterogeneous data into unified patient representations to support clinical outcome prediction. However, real-world medical datasets commonly contain systematic biases from…

Machine Learning · Computer Science 2026-05-19 Xiaoguang Zhu , Linxiao Gong , Lianlong Sun , Yang Liu , Haoyu Wang , Jing Liu

Despite the recent success of domain generalization in medical image segmentation, voxel-wise annotation for all source domains remains a huge burden. Semi-supervised domain generalization has been proposed very recently to combat this…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Muyang Qiu , Jian Zhang , Lei Qi , Qian Yu , Yinghuan Shi , Yang Gao

Deep learning has revolutionized many industries by enabling models to automatically learn complex patterns from raw data, reducing dependence on manual feature engineering. However, deep learning algorithms are sensitive to input data, and…

Machine Learning · Computer Science 2025-07-21 Mert Sehri , Zehui Hua , Francisco de Assis Boldt , Patrick Dumond

Domain generalization aims to learn a prediction model on multi-domain source data such that the model can generalize to a target domain with unknown statistics. Most existing approaches have been developed under the assumption that the…

Computer Vision and Pattern Recognition · Computer Science 2021-09-01 Jin Kim , Jiyoung Lee , Jungin Park , Dongbo Min , Kwanghoon Sohn

Deep neural networks have useful applications in many different tasks, however their performance can be severely affected by changes in the data distribution. For example, in the biomedical field, their performance can be affected by…

Computer Vision and Pattern Recognition · Computer Science 2024-05-30 Pedro Vianna , Muawiz Chaudhary , Paria Mehrbod , An Tang , Guy Cloutier , Guy Wolf , Michael Eickenberg , Eugene Belilovsky

Generalization in generative modeling is defined as the ability to learn an underlying distribution from a finite dataset and produce novel samples, with evaluation largely driven by held-out performance and perceived sample quality. In…

Machine Learning · Computer Science 2026-03-05 Jerome Garnier-Brun , Luca Biggio , Davide Beltrame , Marc Mézard , Luca Saglietti