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We consider the problem of the long time dynamics for a diffuse interface model for tumor growth. The model describes the growth of a tumor surrounded by host tissues in the presence of a nutrient and consists in a Cahn-Hilliard-type…

Analysis of PDEs · Mathematics 2018-10-30 Alain Miranville , Elisabetta Rocca , Giulio Schimperna

In this paper we consider a boundary stabilization problem for the wave equation with interior delay. We prove an exponential stability result under some Lions geometric condition. The proof of the main result is based on an identity with…

Analysis of PDEs · Mathematics 2010-05-17 K. Ammari , S. Nicaise , C. Pignotti

Models of tumor growth, now commonly used, present several levels of complexity, both in terms of the biomedical ingredients and the mathematical description. The simplest ones contain competition for space using purely fluid mechanical…

Analysis of PDEs · Mathematics 2015-06-12 Benoît Perthame , Fernando Quirós , Juan Luis Vázquez

Stability of the zero solution plays an important role in the investigation of positive systems. In this note, we revisit the $\mu$-stability of positive nonlinear systems with unbounded time-varying delays. The system is modelled by…

Dynamical Systems · Mathematics 2015-05-29 xiwei Liu , Tianping Chen

In this paper, we establish the existence of a positive, bounded solution for a class of parabolic partial differential equations with nonlinear boundary conditions, where the boundary conditions depend on the solution on the boundary at a…

Dynamical Systems · Mathematics 2025-07-15 Gangadhara Boregowda , Michael R. Lindstrom

In this paper, the linear stability theory of an incompressible asymptotic suction boundary layer was studied. A small disturbance was introduced spatially in a streamwise direction to the laminar base flow with various wavenumber $\alpha =…

Fluid Dynamics · Physics 2022-08-02 Ressa Octavianty , Triwanto Simanjuntak

Incorporating free boundary into time-delayed reaction-diffusion equations yields a compatible condition that guarantees the well-posedness of the initial value problem. With the KPP type nonlinearity we then establish a vanishing-spreading…

Analysis of PDEs · Mathematics 2021-08-03 Ningkui Sun , Jian Fang

In this article a generalized mathematical model describing the interactions between malignant tumour and immune system with discrete time delay incorporated into the system is considered. Time delay represents the time required to generate…

Tissues and Organs · Quantitative Biology 2015-11-05 Monika Joanna Piotrowska

This paper provides a unified mathematical analysis of a family of non-local diffuse interface models for tumor growth describing evolutions driven by long-range interactions. These integro-partial differential equations model cell-to-cell…

Analysis of PDEs · Mathematics 2021-07-07 Luca Scarpa , Andrea Signori

In this paper, we study the tumor growth equation along with various models for the nutrient component, including the \emph{in vitro} model and the \emph{in vivo} model. At the cell density level, the spatial availability of the tumor…

Analysis of PDEs · Mathematics 2018-02-05 Jian-Guo Liu , Min Tang , Li Wang , Zhennan Zhou

We investigate the long-time dynamics and optimal control problem of a diffuse interface model that describes the growth of a tumor in presence of a nutrient and surrounded by host tissues. The state system consists of a Cahn-Hilliard type…

Analysis of PDEs · Mathematics 2023-07-28 Cecilia Cavaterra , Elisabetta Rocca , Hao Wu

The problem of the onset and growth of solid tumour in homogeneous tissue is regarded using an approach based on local interaction between the tumoral and the sane tissue cells. The characteristic sizes and growth rates of spherical…

Cell Behavior · Quantitative Biology 2007-05-23 R. G. Khlebopros , V. A. Slepkov , V. G. Sukhovolsky , Y. V. Mironov , V. E. Fedorov , S. P. Gabuda

We consider a delay differential equation that occurs in the study of chronic myelogenous leukemia. After shortly reminding some previous results concerning the stability of equilibrium solutions, we concentrate on the study of stability of…

Dynamical Systems · Mathematics 2010-03-23 Anca-Veronica Ion , Raluca-Mihaela Georgescu

We consider a class of tumor growth models under the combined effects of density-dependent pressure and cell multiplication, with a free boundary model as its singular limit when the pressure-density relationship becomes highly nonlinear.…

Numerical Analysis · Mathematics 2018-04-04 Jian-Guo Liu , Min Tang , Li Wang , Zhennan Zhou

In this paper, we consider a multi-layer tumor model with a periodic provision of external nutrients. The domain occupied by tumor has a different shape (flat shape) than spherical shape which has been studied widely. The important…

Analysis of PDEs · Mathematics 2021-09-30 Wenhua He , Ruixiang Xing

This paper develops a new approach to the estimation of the degree of boundedness or stability of multidimensional nonlinear systems with time-dependent nonperiodic coefficients-an essential task in various engineering and natural science…

Dynamical Systems · Mathematics 2022-06-16 Mark A. Pinsky

The goal of the present paper is to study the viscoelastic wave equation with the time delay \[ |u_t|^\rho u_{tt}-\Delta u-\Delta u_{tt}+\int_0^tg(t-s)\Delta u(s)ds+\mu_1u_t(x,t)+\mu_2 u_t(x,t-\tau)=b|u|^{p-2}u\] under initial boundary…

Analysis of PDEs · Mathematics 2021-05-11 Menglan Liao , Zhong Tan

In this paper we study a model describing the growth of necrotic tumors in different regimes of vascularisation. The tumor consists of a necrotic core of death cells and a surrounding nonnecrotic shell. The corresponding mathematical…

Analysis of PDEs · Mathematics 2015-03-17 Joachim Escher , Anca-Voichita Matioc , Bogdan-Vasile Matioc

We study the spatial evolutionary dynamics of solid tumors as they obtain additional driver mutations. We start with a cancer clone that expands uniformly in three dimensions giving rise to a spherical shape. We assume that cell division…

Populations and Evolution · Quantitative Biology 2013-08-08 Tibor Antal , P. L. Krapivsky , M. A. Nowak

We consider the free boundary problem for two layers of immiscible, viscous, incompressible fluid in a uniform gravitational field, lying above a general rigid bottom in a three-dimensional horizontally periodic setting. We establish the…

Analysis of PDEs · Mathematics 2015-10-07 Yanjin Wang , Ian Tice , Chanwoo Kim