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Proton therapy offers superior organ-at-risk sparing but is highly sensitive to anatomical changes, making accurate deformable image registration (DIR) across longitudinal CT scans essential. Conventional DIR methods are often too slow for…
Image reconstruction of low-count positron emission tomography (PET) data is challenging. Kernel methods address the challenge by incorporating image prior information in the forward model of iterative PET image reconstruction. The…
Background: Daily or weekly cone-beam computed tomography (CBCT) scans are commonly used for accurate patient positioning during the image-guided radiotherapy (IGRT) process, making it an ideal option for adaptive radiotherapy (ART)…
Convolutional Neural Networks (CNNs) work very well for supervised learning problems when the training dataset is representative of the variations expected to be encountered at test time. In medical image segmentation, this premise is…
Conventional machine learning systems that operate on natural images assume the presence of attributes within the images that lead to some decision. However, decisions in medical domain are a resultant of attributes within medical…
Photon-counting CT (PCCT) offers improved diagnostic performance through better spatial and energy resolution, but developing high-quality image reconstruction methods that can deal with these large datasets is challenging. Model-based…
Low-dose Computed Tomography (LDCT) reconstruction is an important task in medical image analysis. Recent years have seen many deep learning based methods, proved to be effective in this area. However, these methods mostly follow a…
Image-generative artificial intelligence (AI) has garnered significant attention in recent years. In particular, the diffusion model, a core component of generative AI, produces high-quality images with rich diversity. In this study, we…
Like in many other research fields, recent developments in computational imaging have focused on developing machine learning (ML) approaches to tackle its main challenges. To improve the performance of computational imaging algorithms,…
This study proposes a novel imaging and reconstruction framework for dual-energy cone-beam CT (DECBCT) using only two orthogonal X-ray projections at different energy levels (2V-DECBCT). The goal is to enable fast and low-dose DE volumetric…
Computed tomography (CT) uses X-ray measurements taken from sensors around the body to generate tomographic images of the human body. Conventional reconstruction algorithms can be used if the X-ray data are adequately sampled and of high…
Long lasting efforts have been made to reduce radiation dose and thus the potential radiation risk to the patient for computed tomography acquisitions without severe deterioration of image quality. To this end, numerous reconstruction and…
Cone Beam Computed Tomography(CBCT) is a now known method to conduct CT imaging. Especially, The Low Dose CT imaging is one of possible options to protect organs of patients when conducting CT imaging. Therefore Low Dose CT imaging can be…
Proton Computed Tomography (CT) is a prototype imaging modality for the reconstruction of the Relative Stopping Power of a patient, for more accurate calculations of the dose distributions in proton therapy dose planning. The measurements…
Spectral Photon-Counting Computed Tomography (SPCCT) is a promising technology that has shown a number of advantages over conventional X-ray Computed Tomography (CT) in the form of material separation, artefact removal and enhanced image…
Breast CT provides image volumes with isotropic resolution in high contrast, enabling detection of small calcification (down to a few hundred microns in size) and subtle density differences. Since breast is sensitive to x-ray radiation,…
The use of deep learning has successfully solved several problems in the field of medical imaging. Deep learning has been applied to the CT denoising problem successfully. However, the use of deep learning requires large amounts of data to…
Dynamic computed tomography perfusion (CTP) imaging is a promising approach for acute ischemic stroke diagnosis and evaluation. Hemodynamic parametric maps of cerebral parenchyma are calculated from repeated CT scans of the first pass of…
Deep neural networks have a great potential to improve image denoising in low-dose computed tomography (LDCT). Popular ways to increase the network capacity include adding more layers or repeating a modularized clone model in a sequence. In…
Low-dose computed tomography (CT) has attracted a major attention in the medical imaging field, since CT-associated x-ray radiation carries health risks for patients. The reduction of CT radiation dose, however, compromises the…